Abstract:We propose here to develop tunable diode laser spectroscopy as a diagnostic for the Space Shuttle main engines during test stand operations. These engines represent the state-of-the-art in rocket engine propulsion systems, and as such, they stretch available technology to the limit. The engines must… more
Abstract:ZONA Technology, Inc. (ZONA) proposes a R&D effort to develop a Unified Nonlinear Flight Dynamics and Aeroelastic Simulator (UNFDAS) Tool that will combine proven simulation and visualization techniques to accurately match in-flight recorded dynamic behavior of an air vehicle.
ZONA proposes to… more
Abstract:Conventional air-vehicle designs are subjected to a well-set system/operational requirements. Scramjet-powered vehicle (SPV) design however enters an unprecedented level of multidisciplinary synergy to achieve its operational requirements. Through a convoluted and inverse design strategy for SPV,… more
Abstract:ZONA Technology, Inc. (ZONA) proposes a R&D effort to develop a Parameter-Varying Estimation (PVE) Toolbox that will rapidly evaluate and predict parameters that are required to certify an aircraft during flutter envelope and flying qualities programs. The work carried out successfully during the… more
Abstract:New approaches and techniques are required to effectively monitor and track radiological sources that are currently in use. We are proposing to develop a new class of monitoring and analysis methods that incorporate sensing information collected from zone-aware compact radiation detectors with… more
Abstract:In the production of ethanol from corn, the current process utilizes only the starch. Left unused is a significant amount of by-products, which also are produced during ethanol production. If these byproducts, which are rich in pentose and other sugars, could be made into a valuable product, the… more
Abstract:DESCRIPTION (provided by applicant): The emergence of compact, high-quality digital X-ray imaging detectors, together with nearly exponential growth in computing power and corresponding price reductions, allows for the potential of dedicated 3D breast ima
ging. X-ray mammography (XRM) has… more
Abstract:A novel microbolometer focal plane array is proposed for use at 8-14 m having very low noise, no required thermoelectric stabilization, contrast over a very wide range of object temperature, and projected low cost in manufacture.
Abstract:DESCRIPTION (provided by applicant): A major concern regarding drugs in development is cardiac toxicity. Commonly, drugs in development can cause changes to cardiac contractility, the force with which the heart beats, and cardiac rhythmicity, resulting in
toxic side effects. The purpose of this… more
Abstract:DESCRIPTION (provided by applicant): Our long term aim is to develop a galactosylated and sialylated platelet product that can be stored in the cold in order to prolong shelf life and minimize risk of bacterial growth. Currently, platelets can only be stor
ed at room temperature as platelets stored… more
Abstract:This Small Business Innovation Research (SBIR) Phase I research project aims to develop a point-of-care assay for creatine kinase, an important toxicity biomarker, to screen for adverse drug reactions (ADRs) using whole blood. The assay will utilize bioluminescent resonance energy transfer (BRET)… more
Abstract:DESCRIPTION (provided by applicant): Bacterial and viral meningitis and encephalitis is a major cause of morbidity and mortality in all societies of the world. The rapid progression of symptoms and potentially devastating effect of these diseases necessita
te early recognition and immediate… more
Abstract:Etruscan Executives, Inc. plans to continue the Phase I effort of this SBIR topic by bypassing the issues associated with the traditional use of thermoset plastics in the development of functional large ground-based radomes, instead using thermoplastic materials and innovative manufacturing… more
Abstract:American Maglev Technology, Inc. (AMT) is pleased to respond to the Navy's Advanced Eddy Current Braking Technology STTR. AMT was approached by The University of Texas at Austin Center for Electromechanics (UT-CEM) to team on the development of a replacement for the Navy's high maintenance water… more
Abstract:ATC will build on the lightweight armor development work accomplished in Phase I of the project. The armor design concept includes a gradient structure of ceramics and polymers with embedded ballistic fabrics. The initial testing in Phase I revealed a strong potential for this concept to become the… more
Abstract:HgCdTe, with its high quantum efficiency, remains the material of choice for most high-performance infrared detector applications. By varying its alloy composition, HgCdTe can be used for short wavelength to very long wavelength infrared (VLWIR); however, its use in VLWIR (12-16 microns)… more
Abstract:This Phase II Small Business Innovation Research project will deliver an innovative hydrogen passivation technique for improving manufacturability and performance of HgCdTe infrared detectors. Photon-Assisted Hydrogenation (PAH) causes the substrate to be hydrogenated by simultaneous exposure to… more
Abstract:Over the past 15 years the incidence of in-transit losses in swine during transportation to slaughter has tripled. These losses (non-ambulatory and dead animals) are associated with the rapid accumulation of lactic acid in blood and the development of metabolic acidosis in transport-stressed swine.… more
Abstract:DESCRIPTION (provided by applicant): Targeted delivery of cytotoxic drugs to tumor tissues is an effective strategy to minimize drug exposure of normal tissues and thus improve the toxicity and efficacy profiles of these agents. A tumor targeting system co
nsists of a tumor recognition moiety linked… more
Abstract:DESCRIPTION (provided by applicant): Protein drugs have been approved for many therapeutic indications and represent a rapidly growing segment of the pharmaceutical industry. However, many approved protein drugs and candidates in development fail to reach
their potential efficacy due to suboptimal… more
Abstract:Distributed, collaborative visualization and control of real-time fusion experiments and simulations is of growing importance, because the next major facilities will be internationally located and operated. Currently, collaborative visualization tools for tiled displays in control rooms have… more
Abstract:A flameless personal water heater will be developed that is capable of heating small individual volumes of water for meal preparation, sanitation, or hygiene. The heater will react air and JP-8 in an enclosed flow path and transfer the heat generated to water. The device will be packaged into an… more
Abstract:Solid oxide fuel cells (SOFCs) are attractive candidates to replace conventional diesel-fueled generators and auxiliary power units because of their promise of greater fuel efficiency, efficient operation at part load, and low acoustic signature. With the rapid advancements in SOFC technology,… more
Abstract:The production of hydrogen from coal offers the potential for increased power generation efficiency, reduced pollutant emissions, and the production of valuable chemical products. This project will develop a novel, low-cost, hydrogen membrane with improved durability for the production of… more
Abstract:The USMC has the need for improved military issue sleeping bag systems that reduce the weight to 7.22 lbs and pack volume to 1040 cubic inches. To achieve these significant improvements will require a bottom up redesign of the sleeping bag and evaluation of all components of the system. Finding a… more
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