Abstract:Over the past 15 years the incidence of in-transit losses in swine during transportation to slaughter has tripled. These losses (non-ambulatory and dead animals) are associated with the rapid accumulation of lactic acid in blood and the development of metabolic acidosis in transport-stressed swine.… more
Abstract:DESCRIPTION (provided by applicant): Targeted delivery of cytotoxic drugs to tumor tissues is an effective strategy to minimize drug exposure of normal tissues and thus improve the toxicity and efficacy profiles of these agents. A tumor targeting system co
nsists of a tumor recognition moiety linked… more
Abstract:DESCRIPTION (provided by applicant): Protein drugs have been approved for many therapeutic indications and represent a rapidly growing segment of the pharmaceutical industry. However, many approved protein drugs and candidates in development fail to reach
their potential efficacy due to suboptimal… more
Abstract:Distributed, collaborative visualization and control of real-time fusion experiments and simulations is of growing importance, because the next major facilities will be internationally located and operated. Currently, collaborative visualization tools for tiled displays in control rooms have… more
Abstract:A flameless personal water heater will be developed that is capable of heating small individual volumes of water for meal preparation, sanitation, or hygiene. The heater will react air and JP-8 in an enclosed flow path and transfer the heat generated to water. The device will be packaged into an… more
Abstract:Solid oxide fuel cells (SOFCs) are attractive candidates to replace conventional diesel-fueled generators and auxiliary power units because of their promise of greater fuel efficiency, efficient operation at part load, and low acoustic signature. With the rapid advancements in SOFC technology,… more
Abstract:The production of hydrogen from coal offers the potential for increased power generation efficiency, reduced pollutant emissions, and the production of valuable chemical products. This project will develop a novel, low-cost, hydrogen membrane with improved durability for the production of… more
Abstract:The USMC has the need for improved military issue sleeping bag systems that reduce the weight to 7.22 lbs and pack volume to 1040 cubic inches. To achieve these significant improvements will require a bottom up redesign of the sleeping bag and evaluation of all components of the system. Finding a… more
Abstract:This project will develop highly-insulating, compressive-resistant, adhesive-backed thermal insulation materials, suitable for installation in building construction locations that cannot use existing insulation materials. This compressive resistant material will be used to increase insulating… more
Abstract:One of NASA's primary goals for the next decade is the design, development and launch of a spacecraft aimed at the in-situ exploration of the deep atmosphere and surface of Venus. The success of this mission, called VISE (Venus In-Situ Explorer), is reliant on the development of effective thermal… more
Abstract:Aspen Aerogels Inc. (AAI) and the Man Vehicle Laboratory (MVL) at the Massachusetts Institute of Technology propose to develop nanostructured, lightweight, rubbery aerogel composites for multifunctional insulation materials which will significantly improve advanced extravehicular activity (EVA)… more
Abstract:The Exploration Systems architecture presents some propulsion challenges that require new technologies to be developed. To solve these challenges, NASA needs new technologies for long term cryogenic propellant storage, management and acquisition applications in-space as well as on the lunar surface… more
Abstract:The Sprayable Thermal Insulation for Cryogenic Tanks (STICT) is a thermal management system applied by either an automated or manual spraying process with less sensitivity to process chemistry and environmental parameters than current spray-on foam insulations (SOFI) like BX-265, while providing… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop nanostructured, flexible, inorganic-organic hybrid aerogel composite insulation materials. The proposed material will combine the typical advantages of organic polymers with the advantages of inorganic aerogels, exhibiting… more
Abstract:DESCRIPTION (provided by applicant): Aspen System's long-term objective is to develop, optimize, and commercialize a high performance personal cooling system designed to safely protect workers in military, government, commercial and industrial occupations
from heat stress and heat-related illness… more
Abstract:DESCRIPTION (provided by applicant): Cell Cures' technology utilizes easily isolated and well characterized adult human skeletal muscle stem cells (satellite cells or myoblasts). These striated muscle progenitor cells provide an expandable source of prolif
erating cells which have already been… more
Abstract:DESCRIPTION (provided by applicant): Motivational Interviewing (MI) is a unique style of communication that has demonstrated success with very resistant clients, such as those recovering from drug and alcohol addiction. A growing number of experienced trai
ners in MI now provide training workshops… more
Abstract:The founders of CES have identified three shortcomings of the proposed Integrated Fight Through Power (IFTP) system. The system's lack of galvanic isolation will lead to ship-wide ground fault problems. The system's inability to incorporate alternative power sources (fuel cells or energy storage… more
Abstract:Dust loadings at or above the minimum explosive concentration (MEC) can lead to catastrophic
loss of life and destruction of property. This proposal is to initiate the development of a mass
loading monitor (MLM) that will provide a warning signal when the MEC is approached. The
proposed MLM will… more
Abstract:We propose to use a Holographic Stokese-Meter (HSM) integrated with a conventional focal plane array (FPA) to develop an eye-safe, polarimetric ladar (PLADAR). The HSM is based on angularly-multiplexed volume holographic gratings, first demonstrated by our company, DOT. Incoming optical signal is… more
Abstract:Digital Signal Corporation (DSC) will adapt its current operational Bio-LIDAR 3D face imaging system to SOCOM's application set and 100 Meter range requirements. The Bio-LIDAR is a highly evolved extension of an industrial metrology lidar that produces eye-safe precision 3D measurements at 60 meters… more
Abstract:DESCRIPTION (provided by applicant): Obtaining complete genome DNA sequences of organisms from bacteria to man is a hallmark achievement of 20th century science and has had a huge impact on the biological sciences as well as the practice of medicine. Sequ
ence assembly software played a critical… more
Abstract:Energy Research Company (ERCo) and the University of Texas, Dallas (UTD) propose the development of a novel and highly sensitive eye-safe laser-based standoff sensor technology for detecting films and residues of explosive materials. This sensor detects improvised explosive devices (IEDs), car bombs… more
Abstract:DESCRIPTION (provided by applicant): The ultimate result of the proposed approach will be treatment for rheumatoid arthritis and possibly other diseases caused by the hyperactivity of TNF-a. The approach is to manipulate the alternative splicing pathways o
f the TNF-a receptors (TNFR) pre- mRNA… more
Abstract:DESCRIPTION (provided by applicant): One of the most challenging problems in clinical Dentistry is the loss of alveolar bone. The primary causes of alveolar bone loss are periodontitis and tooth loss. There is also substantial evidence suggesting that ther
e is a link between alveolar bone loss and… more
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