Abstract:DESCRIPTION (provided by applicant): The ultimate result of the proposed approach will be treatment for rheumatoid arthritis and possibly other diseases caused by the hyperactivity of TNF-a. The approach is to manipulate the alternative splicing pathways o
f the TNF-a receptors (TNFR) pre- mRNA… more
Abstract:DESCRIPTION (provided by applicant): One of the most challenging problems in clinical Dentistry is the loss of alveolar bone. The primary causes of alveolar bone loss are periodontitis and tooth loss. There is also substantial evidence suggesting that ther
e is a link between alveolar bone loss and… more
Abstract:The Small Business Technology Transfer Research (STTR) project will develop environmentally friendly composite panels from recycled aluminum cans for beams, frame, roof sections, and floor sections in low cost construction industries. The specific objectives include: specific construction… more
Abstract:The proposed STTR will develop a shock-hardened, autonomous, miniature, wireless multi-channel data acquisition system that is installed in payloads launched from various platforms. The system will be designed to survive impact loads at least ten times higher than those specified in the program… more
Abstract:A sensor is proposed that will allow the robotic system to "see" the frame mounting flange through the inlet duct wall. The ability to directly perceive the location of the flange circumvents the stackup of a number of metrology errors, alleviating the problem of holes in violation of edge margin… more
Abstract:DNA aptamers are promising highly-specific, environmentally-stable threat-detecting molecules. Unfortunately, the current method for generating these materials yields a product frought with a high concentration of ballast aptamers. A laborious, yet automated process is required to isolate the… more
Abstract:Vector borne diseases have posed a significant threat to soldier health in past and present foreign deployments. Currently deployed troops face several severe illnesses such as Leishmaniasis and Sand Fly Fever Virus that are transmitted by insects. There are no prophylactic vaccines available for… more
Abstract:During cold weather operations tasks requiring manual dexterity can become significantly more difficult as the drop in temperature causes capillaries in the fingers to rapidly contract, decreasing skin blood flow and leading to stiff, sore fingers. Infoscitex Corporation (IST) is proposing to… more
Abstract:The main aim of our work is to create a decision support tool that will help keep our troops safer while fighting in far field theatres. We first focus on injuries incurred for troops moving along roads, in armored vehicles, as a result of an improvised explosive device (IED), though our solution… more
Abstract:Hearing protection has advanced to the point where headphones can reliably filter out more than 130 dB of background noise. Coupled with miniature speakers, flight deck personnel can be fed radio transmissions and safe levels of background sound, which allows them to still "hear" dangers such as… more
Abstract:In this Phase I SBIR program Infoscitex is proposing to develop a biomimetic energy absorptive smart armor system to protect our troops and their light armor vehicles against both conventional and unconventional explosion threats. Our approach involves designing and fabricating a variable modulus… more
Abstract:In order to address the U.S. Navy's need for improved tools for use in Anti-Submarine Warfare IST is proposing to develop an advanced acoustic sensing system consisting of networked smart sensor nodes. Each of these sensor nodes will be mobile and able to communicate with nearby sensors to form a… more
Abstract:The main aim of our work is to develop a process and techniques that prevent or delay software piracy and reverse engineering. The Jekyll approach hides the target application in one or more common utility applications or libraries (cover files) making the target application hard to identify, locate… more
Abstract:Current biosurveillance systems monitor limited data sources or utilize rigid rules that limit their effectiveness and flexibility causing problems such as triggering alarms so frequent that they are routinely ignored. Biosurveillance systems today can be improved by utilizing intelligent software… more
Abstract:The Expeditionary Fighting Vehicle (EFV) has two aft mounted exhaust grilles that interface the heat exchangers to the external environment. The current grille design suffers from competing requirements which render its performance less than optimal. In this Phase I project, Infoscitex proposes to… more
Abstract:Underwater vehicles operating in littoral waters face formidable challenges - the shallow waters and relatively high currents present in these regions necessitate a compact vehicle with a considerable amount of internal space and energy devoted to propulsion. Many sensors operate best when somewhat… more
Abstract:Dehydration is a major problem facing our troops, who by necessity are physically active, weighed down by numerous pieces of armor and equipment, and serve in warm, dry climates. Our troops each carry a supply of liquid and are trained to stay hydrated, however this does not guarantee against… more
Abstract:Smoke-producing munitions such as mortars, smoke pots, and hand grenades are an important class of ordnance employed by the US military in both training and mission scenarios. These devices serve a number of vital functions including smoke screening for vision obscurance and marking of targets. A… more
Abstract:Due to the remarkable benefits provided by 802.16 Broadband Wireless Access (BWA) networks, military interest in such technology has consistently grown. However, preplanned base station locations with tall towers and directionally-optimized antennas are not tactically useful. Therefore, in order for… more
Abstract:DARPA topic SB072-038 initiates development of devices that will employ inductive electromagnetic coupling to efficiently transmit power wirelessly over "short to medium" distances, citing a number of advantages relative to other methods, including (1) no requirement for an unobstructed… more
Abstract:Actuation of the jet blast deflectors (JBD) on aircraft carriers will become the dominant user of hydraulic power once the steam catapults are replaced by the Electromagnetic Aircraft Launch System (EMALS). Therefore, the development of sufficiently compact, reliable, and maintainable… more
Abstract:In this Phase I program, the Infoscitex (IST) team focused primarily on the design and fabrication of a prototype high accuracy electro-textile mesh leading to a prototype that weighed 0.42 kg/m2 and provided 99.8 percent reflectivity during testing at 38GHz. Light weight composite fiber core… more
Abstract:The National Aeronautics and Space Administration (NASA) foresee extension of exploratory space missions to the Moon, Mars, Venus and beyond. To reach these outer locations will require development of a range of advanced technologies including life support systems. Food represents one of the most… more
Abstract:Nearly 27,000 soldiers have been injured in the present conflicts in Iraq and Afghanistan. Advances in trauma treatments have allowed a greater percentage of these casualties to survive than previously; with the advent of excellent body armor more injuries are now seen in extremities than before,… more
Abstract:Conventional textiles are currently used in military systems as varied as personal equipment and soft-walled shelters. The Army and other armed forces have recognized the opportunity to greatly enhance the mobility, effectiveness and even lethality of their forces by incorporating electrical… more
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