Abstract:Demonstration of highly efficient 1000W amplifier (405-450 MHz) is proposed in the two-phase program. The first phase is a feasibility phase where a 100W 70% efficiency block amplifier will be demonstrated using GaN HEMT devices and Class F circuit design technology. In phase 2 of the program, the… more
Abstract:DESCRIPTION (provided by applicant): The long term goal of this research is to reduce or eliminate deafness due to certain diseases of the inner ear by developing sustained release formulations for anti-inflammatory drugs which can be implanted directly in
to the inner ear. The initial project will… more
Abstract:DESCRIPTION (provided by applicant): The long term goal of this research is to reduce toxicity and graft rejection due to dosing problems with the calcineurin inhibitors by developing sustained release subcutaneous injectable formulations for the drugs tac
rolimus and cyclosporine. Substantial… more
Abstract:DESCRIPTION (provided by applicant): The broad long term goal of this work is to develop sustained release subcutaneous drug delivery systems in order to achieve a more continuous dopaminergic stimulation in the treatment of Parkinson's Disease (PD). The i
mmediate goal of this project is to develop… more
Abstract:Aurora Flight Sciences proposes to apply algorithms for cooperative tasking of multiple unmanned vehicles, which have been significantly matured in UAVs, to a variety of USV littoral search, inspection, and force protection missions. Because of our mature starting point, the focus will be to… more
Abstract:Aurora proposes to develop a cluttered navigation and control solution, which uses specialized sensing and processing to provide commanded body rates, velocities, etc. to a traditional MAV inner-loop stability augmentation system, thus enabling the MAV to fly urban and other cluttered-environment… more
Abstract:Aurora Flight Sciences (AFS), in collaboration with the Worcester Polytechnic Institute (WPI), propose to develop a low-cost, easily deployed, degradable taggant that can be dispersed over a wide area to serve as a witness to activity in the area and for queuing of other sensors. The passive… more
Abstract:There is interest in an unmanned aircraft that can be deployed to a target via unconventional means and operate at very high altitudes for very long periods of time. These aircraft are envisioned to be stored in a sealed container for many months at a time, possibly folded up, stowed or deflated in… more
Abstract:Extreme HALE (high-altitude, long-endurance) aircraft typically require very long and thin wings. These super-lightweight wings tend to be highly susceptible to elastic instability (i.e., buckling). The maximum load such wings can sustain before buckling is generally much lower than the maximum… more
Abstract:In order to facilitate wider understanding and use of NASA and other scientific data sources through publicly available and familiar tools, such as the Google Maps, Payload Systems Inc. proposes to develop a flexible scientific data search, analysis and visual presentation tool suite. This suite… more
Abstract:Concept phase space-systems architecture evaluations typically use mass estimates as the primary means of ranking potential mission architectures. Software does not directly have physical mass and, as a result, is often left-out of such evaluations, despite the potential of being one of the main… more
Abstract:Payload Systems Inc. and the MIT Space Systems Laboratory propose Self-assembling, Wireless, Autonomous, Reconfigurable Modules (SWARM) as an innovative approach to modular fabrication and in-space robotic assembly of large scale systems. Fabrication of modular components yields fabrication savings… more
Abstract:Aurora Flight Sciences proposes to develop specialized algorithms and software decision-aiding tools for four-dimensional (4D) vehicle-centric, tactical trajectory management (TTM), derived from algorithms developed at the Massachusetts Institute of Technology (MIT) to perform similar functions in… more
Abstract:Payload Systems Inc. proposes the Radiation Target Area Sample Environmental Chamber (RTASEC) as an innovative approach enabling radiobiologists to investigate the real-time, long-term radiation effects on living cells and tissues. Most current research into radiation effects on living cultures is… more
Abstract:Payload Systems Inc. (PSI) and the MIT Space Systems Laboratory (MIT-SSL) propose an innovative research program entitled SPHERES-ISS that uses their satellite formation flight laboratory (Synchronized Position Hold Reorient Experimental Satellites - SPHERES), currently operating aboard the… more
Abstract:We propose the development of automated systems to improve radiobiology research capabilities at NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory (BNL). Current radiobiology experimentation at the NSRL is limited primarily by the amount of time required to manually move… more
Abstract:The machining of structures from materials such as titanium is typically accomplished using end mills and roughing 90 to 95 percent of the material to leave precise, complex features on thin-walled structures. High-speed machining is widely used in the manufacture of parts and reduces labor… more
Abstract:Aurora and MIT propose to develop the architecture, core algorithms, and human interface concepts for a multi-platform, distributed UAV team that responds to requests from field operators for intelligence support. Aurora will build on existing robust distributed tasking algorithms that have been… more
Abstract:Automatika, Inc. proposes to develop MaCS, a high-fidelity manipulator system for use on samm unmanned robot vehicles for use in EOD missions for IED disarming. The system is intended to utilize high-performance joint actuators and allow for easy operator control in cartesian space using a simple… more
Abstract:The proposed advancements of the SAVe ventilator will result in an easy to operate, small, lightweight, inexpensive, compressor-driven ventilator well suited not only to military applications and environments such as a battlefield (under the Tactical Combat Casualty Care doctrine), but civilian… more
Abstract:Autonomous Solutions proposes to increase the speed, accuracy, and overall effectiveness of currently fielded EOD robotic manipulators through 3D visualization and arm automation. ASI will integrate a 3D Flash Ladar camera onto an EOD robotic platform to enable the creation of a 3D model of the… more
Abstract:X-ray computed tomography (CT) is used to evaluate the integrity of solid rocket motors (SRM's) used in the missile defense fleet. There is a need for better visualization of bondlines of materials, and detection of flaws, especially in the SRM's dome region. This problem is due to partial volume… more
Abstract:DESCRIPTION (provided by applicant): Pulmonary fibrosis, a group of incurable lung diseases with high mortality rates, is characterized by inflammatory cell infiltration, fibroblast proliferation, and excessive deposition of extracellular matrix proteins i
n lung parenchyma. Globally, five million… more
Abstract:Exposure to light at critical phases of the circadian cycle is the main stimulus that phase shifts and entrains circadian rhythms. Whereas previous work has concluded that exposure of humans to bright light for an hour or more at the right phase of the circadian cycle produces significant phase… more
Abstract:Hypersonic aircraft are subjected to extreme conditions with respect to mechanical thermal and acoustic loads. Materials with complex microstructure, such as Functionally Graded (FGM) and honeycomb, are expected to play a key role in such vehicles. Detailed numerical stress and thermal analysis of… more
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