Abstract:DESCRIPTION (provided by applicant): Databases of biological sequences have proven valuable for understanding the organization of human and other genomes, for unraveling the etiology of genetic disorders, and for studying medically important pathogens. Unf
ortunately, these databases are growing at… more
Abstract:This project is aimed at helping protect crop productivity by providing a means of rapidly assessing the health of bee colonies used for pollination. We propose research leading to the design of a hand-held device that could scan a honey bee colony, and quickly indicate the condition of that colony.… more
Abstract:"Honey bee pollination is estimated to contribute over $14 billion annually to
agricultural production. Honey bee pollination services in the larger ecosystem are
also of vital importance. However, apiculture in the United States is threatened,
especially by infestations of exotic parasitic mites.… more
Abstract:DESCRIPTION (provided by applicant): The goals of this project are to develop, evaluate, and disseminate a suite of software programs that provide brief interventions for heavy drinking college students: The College Drinker's Check-up (CDCU). The CDCU will
be a revision of the Drinker's Check-up… more
Abstract:DESCRIPTION (provided by applicant): The goals of this proposed research project are to develop, evaluate and disseminate an Internet based (web) application called Overcoming Addictions (OA). OA will be based on the cognitive-behavioral change protocol of
SMART Recovery (www.smartrecovery.org).… more
Abstract:DESCRIPTION (provided by applicant): Hispanic adolescents are at elevated risk for mental health and related behavioral problems. Culturally specific stress is associated with the risk for these problems. The objective of the proposed research is to develo
p a stress assessment inventory for… more
Abstract:DESCRIPTION (provided by applicant): This is a Phase I Small Business Technology Transfer Research (STTR) grant application to support the development of an innovative, online training program to aid in the dissemination of Behavioral Activation, a therapy
for depression (BA). The current… more
Abstract:DESCRIPTION (provided by applicant): This is a Phase I Small Business Innovation Research (SBIR; R43/44) grant application to NIMH to support the development of an innovative, online training program in Panic Control Treatment for Adolescents (PCT-A). The
current application represents a… more
Abstract:DESCRIPTION (provided by applicant): More than 50% of drugs on the market target G protein-coupled receptors (GPCRs). Among the most important of these are drugs used to treat neurological disorders, such as pain relievers, antidepressants and anti-psychot
ics, as well drugs used for… more
Abstract:DESCRIPTION (provided by applicant): Neutrophil recruitment is a central component of inflammation, and there is intense focus on inhibiting the process both for chronic inflammatory disorders and for conditions where inflammation plays a contributory role
, such as atherosclerosis. Chemotaxis - the… more
Abstract:DESCRIPTION (provided by applicant): There is a strong need in drug discovery for cellular assays that better predict human responses to drugs. A key technical hurdle has been the difficulty of incorporating complex tissue architecture and cellular microen
vironments into an assay format that is… more
Abstract:Beltran proposes to develop an advanced methodology for analytical prediction of the long-term durability (25 years) of composite materials to be used in design of military facilities. Phase I Project is to outline a methodology concept relevant to emerging carbon fiber epoxy composite materials… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project addresses the need for improved block trading capabilities in the financial markets. Block trading, or sell-side trading, involves transacting large blocks of stock (for example, 450,000 shares of IBM), while trying to minimize market… more
Abstract:Several possible material and design changes to improve HEL deformable mirrors will be discussed. The principles will apply to Air Force ACDM and BCDM mirrors and to other HEL mirror designs. Simple changes to conventional mirrors and a new mounting technique are evaluated first using highly… more
Abstract:The U.S. Army Aviation Engineering Directorate, Propulsion Drive Systems Branch, has identified the need to replace the antiquated, differential mechanical pressure switch/indicator currently being used in hydraulic system filter applications on all Army helicopters, in favor of newer technology,… more
Abstract:This Small Business Technolongy Transfer (STTR) Phase I research develops an in-home training device that allows a post-stroke patient to undergo rehabilitation with little or no assistance. Approximately 500,000 Americans survive a stroke each year. Miraculously, most stroke survivors can relearn… more
Abstract:Fatigue life of aerospace components is greatly enhanced by planting compressive residual stresses or favorable microstructure in the shallow surface by various processing techniques, including laser shock peening (LSP). In some situations, there are shock-induced defects in the subsurface and other… more
Abstract:In this SBIR proposal, BerrieHill Research Corporation working with the ElectroScience Laboratory and the MicroMD Facility at The Ohio State University shall identify and develop novel magnetic RF polymers that have relatively high permittivity and permeability while exhibiting low loss at… more
Abstract:Variability exists in all objects considered in ATR data sets. The two most important sources of this variability are (1) added or removed objects (example: object attached to the back of a tank) or (2) a part displaced relative to other parts, sometimes referred to as "articulation" (the classic… more
Abstract:An important area of military capabilities is the small unmanned aerial vehicle (UAV). It is inexpensive and controllable by forward units. The Air Force presently has a significant opportunity to improve the productivity of UAV radar systems to provide all-environment detection of camouflaged and… more
Abstract:DESCRIPTION (provided by applicant): Human embryonic stem cells (HuES) have the potential to generate an unlimited source of beta/islet cells for transplantation, however the biologic factors required for this process have been difficult to ascertain partl
y due to the lack of stage specific in… more
Abstract:DESCRIPTION (provided by applicant): The American Cancer Society estimated a total of 1,372,910 new cancer cases and 570,280 cancer deaths in the U. S. in 2005. The National Cancer Institute solicits research proposals to develop cancer treatments via the
Small Business Innovation Research funding… more
Abstract:Game technology can efficiently produce Synthetic Task Environments for training, research and assessment. Typically this technology is exploited with an entertainment-oriented game engine. However a fully functional STE requires features outside the engine's original design. This compels engineers… more
Abstract:An innovative flow control device will be built and tested. Based on cryogenically proven, highly efficient Venturi-Offset Technology (VOST) developed for NASA, it has no stem-actuator, few moving parts, and an overall cylindrical shape. Consistently demonstrating breakthroughs in flow control,… more
Abstract:Two cryogenic flow-control valves of diameters 1/2" and 2" will be built and tested. Based on cryogenically-proven Venturi Off-Set Technology (VOST) they have no stem-actuator, few moving parts, and an overall cylindrical shape. Intended to demonstrate a breakthrough in cryogenic flow control,… more
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