Abstract:This Small Business Innovation Research (SBIR) Phase I project aims to provide an information technology based software system that will support productivity for Tribal grantees using a culturally comprehensible, project management tool. The intellectual merit of this project is an enabling… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop and test a novel system for providing patients in physical and occupational therapy customized visual and aural feedback as a rehabilitation tool. The proposed 'augmented feedback' system will allow therapists to supplement… more
Abstract:This Small Business Innovation Research Phase I research project investigates the feasibility of using Micro-Compliant-Interconnect-Mechanisms (MCIMs) to provide chip level communication to Micro-Electro-Mechanical-Systems (MEMS) devices. MCIMs are microscopic spring connectors fabricated directly… more
Abstract:Novel Li ion batteries with higher energy and power densities, as well as improved stability, are required for use in hybrid/electric vehicles,HEVs, and plug in HEVs, as replacements for the heavier, larger nickel metal hydride batteries. However, Li ion batteries suffer from several problems… more
Abstract:The Small Business Technology Transfer Research (STTR) Phase I project will develop diffusion barriers for organic electronic devices. Innovative new films formed from inorganic/polymer multilayers are excellent flexible gas diffusion barriers to protect organic electronic devices. Current coating… more
Abstract:DESCRIPTION (provided by applicant): The National Institutes of Allergy and Infectious Disease have called for better tools for the detection and diagnosis of emerging and re-emerging infectious diseases. In response to this need, Alderon Biosciences propo
ses research to develop printed disposable… more
Abstract:DESCRIPTION (provided by applicant): The National Institute of Allergy and Infectious Disease has called for better tools for the detection and diagnosis of emerging and re-emerging infectious diseases such as influenza. The need is for tests that are prac
tical and affordable for use at… more
Abstract:DESCRIPTION (provided by applicant): The National Cancer Institute has called for new tools for cancer research and diagnosis that are accurate, practical and affordable. Alderon Biosciences, Inc. proposes to fill this need by developing an open biosensor
platform technology for quantitative… more
Abstract:This Small Business Technology Transfer (STTR) Phase I proposal will develop a process for conformally coating non-woven fibers and fiber-based systems in order to selectively remove toxic pathogens from fluid streams. The chemically treated surfaces of fibers and fabrics made from these fibers will… more
Abstract:Proliferation of nuclear weapons is a serious threat in the world today. One way to determine the presence of
nuclear weapons is to detect neutrons emitted by special nuclear material(SNM) such as highly enriched
uranium and weapons grade plutonium. The purpose of this project is to develop improved… more
Abstract:New technology is needed for nondestructive inspection (NDI) of defects in metallic components on aircraft. Small cracks and flaws in multilayer components near rivets and fasteners are a particular concern. Other problems include detecting and characterizing small defects in highly confined areas.… more
Abstract:Gamma-ray spectrometers consisting of inorganic scintillators coupled to optical detectors such as photomultiplier tubes (PMTs) are an important element of the systems that are used to monitor and prevent the spread of special nuclear materials. Two very important requirements for the scintillation… more
Abstract:DESCRIPTION (provided by applicant): Radiation Monitoring Devices ( RMD') is developing a digital radiographic imaging technology that is based upon a semiconductor x-ray receptor. The more specific, targeted application is mammographic imaging (including
breast tomosynthesis) for which the… more
Abstract:Available digital dosimeters are bulky and unable to provide real-time monitoring of dose for space radiation. The complexity of space-flight design requires reliable, fault-tolerant equipment capable of providing real-time dose readings during a mission, which is not feasible with the existing… more
Abstract:OBJECTIVE: Develop innovative scintillator materials for the detection of gamma-ray or neutron radiation for a variety of applications. For handheld and arrayed detectors criteria for improvement include better energy resolution; higher light output (photons per MeV); improved linearity of light… more
Abstract:Monitoring space radiation and the dose received by astronauts is important, especially for future long-duration missions. Neutrons contribute a significant component to the total radiation dose during solar events. We propose to develop a rugged, compact, lightweight, non-hazardous CMOS-based… more
Abstract:The goal of this work is to develop a novel Raman scattering spectrometer for advance standoff detection of IEDs and suicide bomber threats. When using the proposed instrument, we will obtain rapid, chemical-specific analysis at standoff distances of up to 30 m. This instrument will have… more
Abstract:High spatial resolution, LIDAR images of underwater targets from air and submersed platforms are plagued by poor signal-to-noise ratios (SNR), arising from strong scattering in the turbid media of seawater. A hybrid system that combines the detection and coherent signal processing techniques of… more
Abstract:New technology is needed for the nondestructive inspection (NDI) of defects in gas turbine engines. This is particularly true for components such as turbine blades with fretting fatigue defects that are difficult to detect and characterize with existing NDI equipment. The lack of detailed flaw… more
Abstract:Current state-of-the-art X-ray imaging detectors use energy integration, where the simple integration of X-ray events during the exposure period forms images. Unfortunately, such indiscriminate operation is sub-optimal for digital radiography or CT imaging because of its inability to reject scatter… more
Abstract:Radiation Monitoring Devices, Inc. (RMD), in collaboration with Harvard University and Raytheon, proposes to develop a silicon-based focal plane array with single-photon responsivity at 1064-nm, with the goal of creating next-generation LADAR receivers. This Phase I effort will demonstrate the… more
Abstract:DESCRIPTION (provided by applicant): Microfluidic chips, fabricated from low cost polymers, are a promising, emerging technology for synthesis and study of new molecular imaging probes. These chips can contain a variety of microcircuitry and microwells and
are capable of manipulating nanoliter… more
Abstract:High flux flash X-ray systems provide unique methods of imaging ultra-fast events that cannot be captured using normal photographic techniques. X-ray images can be obtained in 20 to 50 nanoseconds, even through smoke, fire, and metal, and enable precise recording of details of test events under the… more
Abstract:With the ever-increasing number of human disease models, particularly models in smaller animals, high-resolution emission/transmission tomography techniques have become extremely important. The barriers to using existing modalities in studies of laboratory animals have traditionally been poor… more
Abstract:The use and applications of radiological sources, for power, medical, and defense applications, continuously increases with time. Illicit nuclear materials represent a threat for the safety of the American citizens and the detection and interdiction of a nuclear weapon is a national problem that… more
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