Abstract:ZIN Technologies, Inc will breadboard an integrated electronic system for space suit application to acquire images, biomedical sensor signals and suit health & status data. The system will then process, display, store, transmit and manage the results under control of embedded firmware. A commercial… more
Abstract:ZIN Technologies, Inc. is developing a novel Miniature Treadmill with resistive exercise capability for use in spaceflight exercise countermeasures and broad terrestrial therapeutic applications. The treadmill offers excellent periodic impact exercise to stimulate bone remodeling and cardiovascular… more
Abstract:Ziva with team member UCSD propose a ground-breaking new micro-scanning technology capable of rapid scanning over a wide Field of Regard while reducing the size, weight, and power by 10 - 100x compared to conventional scanning technologies, making it ideally suited to micro-vehicle applications,… more
Abstract:ZAI proposes to investigate advancing the capabilities of our Smart Towed Vehicle to be mounted and operated onto a more diverse range of aircraft and applications. Currently the STV has been fully tested and operated on a Twin Otter. During Phase I ZAI will look at mounted options for other… more
Abstract:We will develop a compact THz system with standoff spectroscopic detection capability, using an intense 1-μm Yb fiber laser with a tilted optical pulse wave-front to excite a nonlinear optical crystal (such as, LiNbO3) as the THz emitter, and a balanced electric-optic (EO) crystal incorporated… more
Abstract:This Small Business Innovation Research Phase I research project proposes to develop a Compact TeraHertz (THz) Air-Breakdown-Coherent Detection (ABCD) Spectrometer. Specifically, this research will construct and integrate this THz spectrometer based on recent experimental and theoretical research on… more
Abstract:The ZONA Team proposes to develop a nonlinear aeroelastic/aeroservoelastic methodology for free-play (FP)/LCO analysis and prediction for aircraft control surfaces at various trim conditions and subjected to gust/pilot commend excitations. In phase I, a CartEuler-based FP/LCO methodology (CEFM) will… more
Abstract:A novel approach is proposed for the suppression of the aircraft's structural vibration to increase the resilience of the flight control law in the presence of the aeroelastic/aeroservoelastic (AE/ASE) interactions. Currently aircrafts with non-adaptive control laws usually include roll-off or notch… more
Abstract:ZONA Technology proposes to develop an innovative nonlinear structural reduced order model (ROM) - nonlinear aerodynamic ROM methodology for the inflatable aeroelasticity of a clamped modeled ballute system. The proposed ROM-ROM methodology tightly couples a nonlinear-FEM based structural ROM with… more
Abstract:ZONA Technology, Inc (ZONA) and Arizona State University (ASU) propose a R&D effort to develop a ground flutter testing system without wind tunnel, called the Dry Wind Tunnel (DWT) system. The DWT system consists of a ground vibration test (GVT) hardware system and a real-time unsteady aerodynamic… more
Abstract:ZONA Team proposes in Phase II to develop a general nonlinear methodology with a new and expedient reduced-order-modeling-based procedure as well as direct numerical simulation capability for nonlinear aeroelastic design/analysis of air-vehicles and MAVs under continuous dynamic morphing The… more
Abstract:Sequestering CO2 in geologic formations in the earth is a promising approach to reducing CO2 in the atmosphere and thereby slowing global warming. In these formations, it is important to understand where the CO2 is going and to assure that the sequestered CO2 is permanently contained.… more
Abstract:Sequestering CO2 in geologic formations in the earth is a promising approach to reducing CO2 in the atmosphere and thereby slowing global warming. In these formations, it is important to understand where the CO2 is going and to assure that the sequestered CO2 is permanently contained. Seismic… more
Abstract:When ethanol is produced from corn, only the starch is transformed, and a significant amount of byproducts is produced. If these byproducts, which are rich in sugars, could be made into a valuable product, the cost-effectiveness of ethanol production will be enhanced. One such potential product is… more
Abstract:This SBIR Phase I project will develop a hand-held sensing and alarm system for ultra-trace concentrations of chemical gases, biological aerosols, and explosive vapors. Unprecedented sensitivity will be achieved by differential intracavity laser absorption spectroscopy (ICLAS) which provides up to… more
Abstract:During the Phase-I research we only spent 6 months (not 9 months) an air droppable rolling weight deflectormeter (ADRWD) was built and a conceptual demo at a small airport was successfully conducted. The Phase-II main objective is to refine the Phase-I design and build a lightweight working ADRWD… more
Abstract:DESCRIPTION (provided by applicant): Pathological angiogenesis, the growth of new blood vessels during a disease state, contributes to over 70 diseases, including cancer. The proposed studies are a Phase II SBIR grant application focused on the preclincal
development of novel anti- angiogenic small… more
Abstract:DESCRIPTION (provided by applicant): Kaposi's sarcoma is the most common cancer associated with HIV infection. It is caused by infection with Kaposi's sarcoma-associated herpesvirus (KSHV). In patients with HIV infection as well as in non-HIV-infected orga
n transplant recipients who are… more
Abstract:DESCRIPTION (provided by applicant): The objective of this project is to continue developing an adenoviral vector vaccine against CEA that is effective in stimulating cell-mediated immunity in animals previously immune to adenovirus. The Ad-CEA vaccine en
dpoint is to treat patients with CEA… more
Abstract:DESCRIPTION (provided by applicant): The Bcl-2 family proteins are key effectors of cancers. Recent studies indicate that Myeloma cell factor-1(Mcl-1), a member of this protein family, is a key regulator of lymphoid cancers including B-cell lymphoma, mul
tiple myeloma, and chronic lymphocytic… more
Abstract:DESCRIPTION (provided by applicant): Eva Pharmaceuticals, STTR Phase II Application, April 2007, Abstract Since their discovery, COX-2 inhibitors have dominated the market for non-steroidal anti-inflammatory agents (NSAIDs). In 2004, Vioxx(r), a major COX-
2 inhibitor, was removed from the… more
Abstract:DESCRIPTION (provided by applicant): In responding to HazMat emergencies, practice not only makes perfect, it also saves lives. Under the Phase I SBIR grant, Amethyst Research developed a software simulation tool called HazCommand. Our Phase II goal is
to create a model platform for… more
Abstract:DESCRIPTION (provided by applicant): Many recent studies have demonstrated the efficacy of interstitial ablative approaches for the treatment of hepatic tumors, including chemical ablation, cryoablation, and thermal ablation using energy sources like RF, l
aser, microwave, or focused ultrasound.… more
Abstract:DESCRIPTION (provided by applicant): High-Intensity Interstitial Ultrasound for Thermal Ablation of Uterine Fibroids. Benign uterine tumors (fibroids) are clinically apparent in up to 50% of women and typically require surgical removal of symptomatic fibr
oids or hysterectomy. Treatment options for… more
Abstract:DESCRIPTION (provided by applicant): This project proposes unique column packings for the fast high-performance HPLC of biomacromolecules. Initial focus will be on developing techniques to modify the chemistry of silica surfaces using hydrothermal methods,
so that biomolecular separations are… more
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