Abstract:DESCRIPTION (provided by applicant): This proposal intends to advance the regional delivery of a chimeric adeno-associated virus (rAAV)-based, highly-truncated dystrophin (minidystrophin) gene therapy for the treatment of Duchenes Muscular Dystrophy (DMD).
Experiments focus on completing… more
Abstract:Aspen Systems proposes to develop a modular cooling system for mobile electronics applications. This system will be highly adaptable and have the capability to maintain lower than ambient temperatures in mobile and stationary electronics enclosures that are deployed to hot desert environments. … more
Abstract:Aspen Systems Inc. proposes to develop a proprietary antenna cooling system for Satellite Communications on-the-move (SATCOM OTM) applications. This system will replace an existing thermal control unit with a lighter and higher performance system designed to keep the antenna electronics cooler than… more
Abstract:To enable the integration of high power electronics into future military platforms, an efficient compact condenser technology which is compact, lightweight, and efficient is needed to remove waste heat from these electronics. Aspen Systems endeavors to meet this need by proposing an advanced… more
Abstract:DESCRIPTION (provided by applicant): This NIDA STTR reapplication is to develop a personal digital assistant (PDA) format of a validated child self- report (Assessment of Liability and EXposure to Substance use and Antisocial behavior(c) or ALEXSA(c)) for
early harmful substance use, antisocial… more
Abstract:This project has two goals: (1) to develop and evaluate the feasibility of intelligent, computer-based self-management and household management applications that would improve the independent living capacity of persons with cognitive disabilities, and (2) to identify an agenda for full development… more
Abstract:This project will examine the feasibility of using alternative modes of execution on x86 processors as a means of providing protection for sensitive applications. The research will aim to answer two main questions: 1) can alternate modes of execution provide an environment that is suitable for… more
Abstract:This proposal addresses the need for a smart, network-compatible, enhanced head-aimed video sensor system to enable geo-location and target hand-off from robotic platforms. The sensor system provides enhanced remote situational awareness, with specific features aimed towards reconnaissance and… more
Abstract:The objective of the Phase 1 and 2 SBIR Topic N06-040, "Ultra-Wide Band Antenna (UWBA) For Electronic Attack Aircraft", is to provide to the Navy innovative, new, and advanced techniques to increase the band coverage of the improved tactical Jamming Systems aboard the EA-6B and EA-18G aircraft (see… more
Abstract:The Air Force Research Laboratory Air Vehicles Directorate needs to be able to rapidly develop hypersonic vehicle concepts and to do so with as little risk as possible. A new technology called Rapid Prototyping will assist the Air Force in reducing risk in choosing the best path for fielding… more
Abstract:We propose to develop a critical enhancement to an existing interactive task guidance system, integrating the capability to utilize data from sensors and control actuators. The system will allow caregivers or rehabilitation professionals to incorporate sensors and actuators into a task script in… more
Abstract:This proposal addresses the development of a new strain gage calibration methodology to help increase the accuracy of structural life estimation in naval aircraft. After understanding the current fatigue life testing procedures, we will develop economical and time-efficient loading mechanisms to be… more
Abstract:A novel quiet engine air-brake is proposed in response to NASA's solicitation for concepts for active and passive control of noise sources for conventional and advanced aircraft. The air-brake concept is applicable to 1) next-generation, conventional tube and wing aircraft (current generation +1)… more
Abstract:This SBIR Phase II proposal addresses the development of a combined near-field acoustic holography (NAH)/beamforming (BF) system to characterize jet noise sources from military aircraft. The hardware and software designs are motivated by requirements set by the Air Force Research Laboratory (AFRL)… more
Abstract:DESCRIPTION (provided by applicant): This is a SBIR Phase II application for developing microfluidic microchips containing 30k protein kinase (PK) substrate peptides for proteomic PK profiling of cell lysates. In recent years there has been a dramatic expa
nsion in our understanding of PK (kinome)… more
Abstract:Bio-ethanol penetration into the marketplace is limited by its cost, making it non-competitive with petroleum-based fuels. Energy consumed during fermentation and distillation steps accounts for 17% of the total cost. Because fermentation is exothermic, the reactor must be cooled to preserve… more
Abstract:DHS is committed to strengthening interest in science and technology (SandT) studies and career choices, and in elevating SandT understanding within various populations. One of the expected learning facilitators is a wealth of contemporary scientific information and discoveries emanating from DHS… more
Abstract:The "smart dust" micro-radio concept developed by DARPA provides an outstanding demonstration of the potential of distributed micro-sensor networks connected by low-power radio frequency (RF) data links in a self-organizing network. Distributed micro-sensor and control networks are poised to become… more
Abstract:DESCRIPTION (provided by applicant): This SBIR Phase I project defines and implements a new class of technology-enabled science and environmental health science (EHS) 9-12 teacher support. The proposed innovation is called Teachers iPod or TiP. The goals o
f TiP are to: (1) prepare teachers to be… more
Abstract:Athena Technologies Incorporated (Athena) proposes to demonstrate a watercraft recovery control system to control, monitor and manage the recovery sequence of watercraft aboard small surface combatants. The solution leverages Athena's capabilities in vision-augmented estimation, control and path… more
Abstract:Aluminum alloys are known to suffer from Stress Corrosion Cracking(SCC). SCC of high strength alloys can proceed rapidly, and can lead to devastating structural failures. However, a solid understanding of combined interactions of metallurgical, environmental and mechanical factors surrounding the… more
Abstract:DESCRIPTION (provided by applicant): Many human diseases have been traced back to single genetic mutations in the genome that are causative for the disorder, such as Lesch-Nyhan Syndrome, Cystic Fibrosis, Tay-Sachs disease and Duchenne muscular dystrophy.
The goal of this proposal is to proof the… more
Abstract:Connecting deep submergence systems (submarines) in the field can be a dangerous and difficult task. The rigid piping systems used today have little flexibility to accommodate for variations in connection points and differences in tolerances between vessels. Atkins & Pearce, a 200 year old… more
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