Abstract:DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I project will develop a reagentless biosensor for online monitoring of microbial contaminants in drinking water. The biosensor is based on incorporating several newly emerg
ing technologies into BioDetection… more
Abstract:DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I project will develop an innovative biochip for rapid screening of pesticide residues in water and food samples. The proposed biochip will be built on BioDetection Instrume
nts' exclusively-licensed patented… more
Abstract:DESCRIPTION (provided by applicant): In this Phase II project, BlueInGreen, LLC will build a hypersaturated dissolved ozone (HYDOZTM) unit to deploy in a large pilot-scale study at Springdale Wastewater Treatment Facility (SWWTF) in Springdale, Arkansas. F
urthermore, BlueInGreen will collaborate… more
Abstract:Beacon's vision for this Topic is the creation of an Automated Decision Support & Maintenance Activity Performance Support system. The solution will be fully integrated into the Afloat Network, providing data capture and analysis, decision-support, the ability to take action on the decisions… more
Abstract:In meeting the needs of this Topic, Beacon will create technology that works across the spectrum of maintenance. The Maintenance Action Package is being designed to fit at the juncture of system automation and human interaction. The "Automation" refers to creating a highly flexible gathering of… more
Abstract:A high-brightness elliptic electron or positron beam is a novel device that has wide applications in high energy accelerators. In addition to the high-energy accelerator applications, high-brightness elliptic charged-particle (electron, muon, proton, antiproton, and ion) beams have wide applications… more
Abstract:The multiple beam inductive output tube (MB IOT) will play a vital role as a high-power microwave source to drive the accelerator cavities used in future free electron lasers for military systems. There is a great deal that is still unknown about the complex beam wave interaction inherent in… more
Abstract:The objective of this proposal is to demonstrate the ability of Beaver Aerospace and Defense to decrease the weight and cost of aircraft actuators while increasing their reliability. Aircraft actuators are a significant cost and safety concern to the Department of Defense. Beaver Aerospace and… more
Abstract:NASA has many needs for maintenance and repair technologies for long-duration human space missions. We propose to continue developing a compact, portable, vacuum-compatible, multi-axis Manipulator/Machining Center (M/MC) to satisfy many of NASA's needs. Our M/MC will provide complex manipulation… more
Abstract:The Navy is looking to develop a method for notching out tunable frequency bands from the output of a high power wideband jammer. The notches must be synchronized with rapid frequency hopping radios, tuning within 1 KHz in less than 1 uS. The method must support at least 8 notches, each reducing… more
Abstract:DESCRIPTION (provided by applicant): This is a Phase I Small Business Innovation Research (SBIR) grant application to support the development of an innovative, online training program to aid in the dissemination of exposure therapies (ETs) for anxiety diso
rders. ETs have consistently and robustly… more
Abstract:DESCRIPTION (provided by applicant): This is a Phase I Small Business Innovation Research (SBIR; R43/44) grant application to NIMH to support the development of an innovative, online training program in Panic Control Treatment (PCT). The current applicatio
n represents a cooperative partnership… more
Abstract:DESCRIPTION (provided by applicant): Persons with severe and persistent mental illness (SPMI) commonly experience both Substance Use Disorders (SUDs) and Borderline Personality Disorder (BPD), resulting in serious and complex personal costs and public heal
th problems. Although Assertive Community… more
Abstract:DESCRIPTION (provided by applicant): This is a Phase II Small Business Innovation Research (SBIR; R43/44) grant application to NIMH to support the further development and testing of an innovative, online training program in Panic Control Treatment for Adol
escents (PCT-A). The current application… more
Abstract:DESCRIPTION (provided by applicant): Interpersonal Psychotherapy (IPT) is one of the most thoroughly validated psychosocial treatments for depression. Dissemination of IPT, however, has been hindered by lack of trainers and didactic materials. Though sever
al excellent textbooks regarding IPT are… more
Abstract:DESCRIPTION (provided by applicant): Methylation is a ubiquitous and reversible covalent modification used to control the function of diverse biomolecules including their activity, stability and localization. Like phosphorylation, methylation is used to mo
dulate protein function, but in addition… more
Abstract:DESCRIPTION (provided by applicant): There is a high level of pharmaceutical interest in targeting enzymes that catalyze oxidation and reduction reactions for therapeutic intervention. Validated redox enzyme targets include HMG-CoA reductase, the target of
statin drugs like Lipitor that are used to… more
Abstract:DESCRIPTION (provided by applicant): In less than one year the 1918 Spanish flu pandemic claimed over 20 million lives worldwide, killing 675,000 Americans, more than 10 times the number of deaths to US servicemen in World War I. A similar strain of the vi
rus that caused the 1918 pandemic could… more
Abstract:Currently, there is no standardized process for assessing the accessibility of recreation elements used for outdoor recreation, picnic and camping facilities although standards for specific outdoor recreation elements exist, the Forest Service Outdoor Recreation Accessibility Guidelines and the… more
Abstract:Cities must perform detailed assessments of sidewalks and streets, including curb ramps, pedestrian signals, crosswalks, street furniture, and other components to determine compliance with the Public Rights-of-Way Accessibility Guidelines. However, current assessment methods are inadequate or… more
Abstract:The objective of this program is to develop adaptive optic laser mirrors which exhibit minimum distortion when irradiated with high power laser flux. Two approaches will be tried utilizing two sets of previously selected candidate materials. Results will indicate how to significantly improve the… more
Abstract:DESCRIPTION (provided by applicant): The primary long-term goal of this project is to develop a useful, practical, valid, and reliable tool to improve the quality of life (QOL) of people in dementia care settings. Specific objectives of this project includ
e developing and evaluating user-friendly… more
Abstract:DESCRIPTION (provided by applicant): This project will modify an existing emailed program to improve diet and physical activity (PA), by making it more appropriate for workers 55-64 years of age and by adding the ability to deliver automated interactive t
elephone messages and printed materials… more
Abstract:This Small Business Technology Transfer (STTR) Phase I research project proposes the development of the design features, sensory system and the control algorithm of an integrated powered knee-ankle power regenerative prosthesis. Despite significant advances in lower limb prosthetics over the past… more
Abstract:This Small Business Technology Transfer Phase I project seeks to create exoskeleton assist devices for workers in distribution centers and automobile assembly plants. By using these assistive devices, workers can dramatically reduce the load in the vertebrae of the lower back when maneuvering parts… more
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