Abstract:Aerosol particles have important impacts on visibility, acid deposition, climate, and human health. A large fraction of these aerosols are generated from energy-related activities, and these organic compounds are known to constitute a significant fraction of ambient aerosol mass. Recently… more
Abstract:Exploration of planetary surfaces will require a communication architecture that supports operational capabilities in which fixed and mobile assets on the planetary surface can communicate seamlessly and securely. Aeronix understands the issues and believes that it can leverage it knowledge and… more
Abstract:The Space Network presents severe challenges that will not allow simple reliance on technology transfer from the general Internet. Rather, addressing the problems confronting the Space Network will require the integration of a wide range of developing technologies to support assured, robust… more
Abstract:Aerophysics, Raytheon Missile Systems, and Michigan Tech Research Institute (MTRI) have teamed to provide an innovative solution that will detect, track, and neutralize small UAVs. The system, termed Peregrine, is a RADAR-cued active/passive IR countermeasure based on the Quiet Eyes turret from… more
Abstract:The objective of this proposal is to design, construct and test a high-frequency-response air-data probe, the Fast Response Atmospheric Turbulence probe (FRAT probe) that will be able to operate in harsh and humid atmospheric environments. Both requirements, high-frequency response and resistance to… more
Abstract:DESCRIPTION (provided by applicant): Our parent project aims to develop a small, lightweight, battery-powered collector suitable for time-resolved personal and micro-environmental monitoring of the chemical constituents of airborne particles. This revision submission aims to enhance that… more
Abstract:Wake vortices are a critical constraint to aircraft separation and therefore airportal throughput, which is already at or near capacity at many major airports in the NAS. Improvements to current methods of spacing aircraft could significantly increase airportal capacity, but there is currently… more
Abstract:FAA predicts that air traffic will double or even triple by 2025 and unless solutions that enable improvements in the use of airspace can be developed and implemented, significant airspace congestion will occur. Advancements in aircraft capabilities via new technologies can enable aircraft to… more
Abstract:The primary benefits of SimBLOX to the public are that it helps private and government organizations become better stewards of taxpayers' dollars and it protects our natural resources. The proposed research and resulting proof-of-concept model for this Phase I effort has enormous potential to assist… more
Abstract:Most project management (PM) tools on the market today use some type of PERT and/or CPM methodology as its primary underlying methodology. PERT (Program Evaluation and Review Technique) was invented by the U.S. Navy in the 1950''''''''''''''''s to manage the Polaris submarine missile program. CPM… more
Abstract:DESCRIPTION (provided by applicant): Tracing techniques have long been used to analyze specific neural pathways but do not reveal their function. Lesion techniques have also long been employed to analyze the function of neural pathways but are not very sel
ective. Current lesion methods use… more
Abstract:Rather than continuing to approach cyber security problems in a reactive fashion, ASD proposes to move to a proactive posture; anticipating and eliminating vulnerabilities while also being prepared to effectively and rapidly defend against attacks. Our approach collects data about the attacker as… more
Abstract:DESCRIPTION (provided by applicant): In addition to the role oral infections play in promoting tooth loss, periodontitis has also been associated with increasing the risk of other medical conditions such as coronary artery disease, stroke and myocardial i
nfarction. Approximately 50% of the US… more
Abstract:DESCRIPTION (provided by applicant): Over 6.3 million fractures occur each year in the United States alone (Praemer et al. 1999) and approximately 15% of fractures exhibit delayed or impaired healing. The clinical applications currently used to treat dela
yed fracture require open surgery to insert… more
Abstract:DESCRIPTION (provided by applicant): Of the nearly 5 million patients who visit a physician for tendon pain each year in the US, approximately 200,000 go on to have a surgical repair. And while surgical repair has a high-rate of symptom relief, recovering
patients are routinely immobilized for… more
Abstract:DESCRIPTION (provided by applicant): Infection surrounding metal implants is a common and sometimes devastating cause of implant failure in a number of fields including oral, craniomaxillofacial (CMF), orthopedic, and cardiovascular surgery. These infectio
ns, which arise from the establishment of… more
Abstract:DESCRIPTION (provided by applicant): Mediastinitis is a common and sometimes devastating complication following open heart surgery. Despite the use of prophylactic systemic antibiotics and improved surgical techniques, bacterial infection remains a serious
complication following almost all surgical… more
Abstract:DESCRIPTION (provided by applicant): Chronic wounds are a significant public-health problem, imposing a high cost on society and presenting patients with significant quality of life limitations. A large proportion of patients with chronic wounds, such as d
iabetic foot ulcers, and venous leg ulcers,… more
Abstract:DESCRIPTION (provided by applicant): Ventriculoperitoneal (VP) shunts are used to treat pediatric and neonatal hydrocephalus in severe cases, representing approximately 1/3rd of affected infants. Due to the high susceptibility for infection and mechanical
breakdown, the failure rate of VP shunts is… more
Abstract:DESCRIPTION (provided by applicant): Summary Targeted drug delivery has been a long-term goal for biomedical science. Of specific interest, are those drugs which exert powerful therapeutic effects but cannot be prominently used due to harmful side- effects
during systemic delivery? Bone has become… more
Abstract:This project will extend the microchannel resonator to the level of a few attograms, which will allow measurement of individual particles as small as 10 nanometers with unprecedented resolution. The Phase I effort will prove the feasibility of this approach by miniaturizing the MEMS sensors, thereby… more
Abstract:DESCRIPTION (provided by applicant): We propose to develop an inexpensive high-throughput means of selecting and identifying antibodies to both unmodified and modified protein, peptide, and non-peptide antigens. The specific goals of this proposal are to
complete a proof-of-concept using aqueous… more
Abstract:We are proposing to develop a prototype system for identifying subjects on the move utilizing multiple biometrics with a very high
probability of identification. The system would contain cutting edges sensors and technology. This system would also serve as a system for testing subject user… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop a cell and blood compatible, non-clotting drug-eluting prosthetic artery that can release, in a controlled manner, drugs or other small compounds that can inhibit scarring and clotting. Potential drug candidates will be… more
Abstract:DESCRIPTION (provided by applicant): In the United States, it is estimated that 8 million people suffer from peripheral artery disease (PAD). PAD is characterized by a gradual reduction in blood flow to the muscular arteries of the lower extremities caused
by atherosclerosis. For those with severe… more
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