Abstract:By drastically reducing the physical footprint of a mass spectrometer to the size of a beverage can, Ceramitron could set a new performance/price standard in the miniaturized MS market. To do this, we propose eliminating the turbomolecular and roughing pumps in favor two chemical sorption pumps (a… more
Abstract:DESCRIPTION (provided by applicant): The ultimate goal of this Small Business Innovation Research project is to develop the first generation extraocular muscle prosthetic device designed to correct paralytic strabismus. The focus of Phase I of this project
is to refine the design of the prosthesis… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project aims to develop the industry's first catheter-based stroke treatment device that serves both as a blood clot-retrieval as well as a clot-filtering device. Stroke is a major economic burden on the tax payer costing $65.5 billion/year. The… more
Abstract:DESCRIPTION (provided by applicant): This proposal describes the development of hyperpolarized-129Xenon (HP-Xe)-based probes for magnetic resonance imaging (MRI) of two biomarkers of inflammation and brain injury, the peripheral benzodiazepine receptor (PB
R) and the neurotrophic protein, S100B.… more
Abstract:DESCRIPTION (provided by applicant): Cataract surgery is a common procedure that results in removal of the human lens and its replacement with an intraocular lens (IOL). It is a safe procedure, but complications do occur. Many new IOLs are being designed t
o further improve vision after cataract… more
Abstract:DESCRIPTION (provided by applicant): Cataract surgery is a common procedure that results in removal of the human lens and its replacement with an intraocular lens (IOL). It is a safe procedure, but complications do occur. Many new IOLs are being designed t
o further improve vision after cataract… more
Abstract:Recent advances in conductive composites and coatings in the form of electromagnetic shielding materials by Metal Matrix Composites Company now make it possible to scale up the technology insertion opportunities to the stage of advanced commercialization and manufacturing. The materials described… more
Abstract:Plasma-liner-driven magneto-inertial fusion (MIF) is an emerging concept for practical inertial fusion facilities that may one day provide an abundant source of carbon-free energy. For this concept to be successful, it will be necessary to achieve high momentum and high Mach number plasma jets, in… more
Abstract:DESCRIPTION (provided by applicant): ABSTRACT: This application is a Phase I/Phase II Fast-Track SBIR application. Osteoarthritis (OA), the clinical syndrome of joint pain and dysfunction caused by joint degeneration, affects more people than any other joi
nt disease. There are no consistently… more
Abstract:The world is increasingly concerned about global warming from the greenhouse effect, and the voluminous CO2 emissions from human activities are a significant contributor to this problem. Carbon sequestration is the concept of isolating and removing CO2 gases from large point sources and then… more
Abstract:NuGen Mobility successfully demonstrated that its innovative technology for Integrated Starter Generator (ISG) applications offered significant benefits providing a cost effective solution while maintaining performance with higher efficiencies as compared to typical industry standards. As a… more
Abstract:NuGen Mobility successfully demonstrated that its innovative technology for Integrated Starter Generator (ISG) applications offered significant benefits providing a cost effective solution while maintaining performance with higher efficiencies as compared to typical industry standards. As a… more
Abstract:The primary objective of the proposed research program is to realize a miniature, high-speed, low voltage hybrid photonic crystal waveguide modulator based on state-of-the-art electro-optic polymers with electro-optic coefficients on the order of 200pm/V as well as innovative poling, leading edge… more
Abstract:The overall goal of this proposal is to develop a large area updateable 3D color display using unique photorefractive (PR) polymers with fast writing times (ms), long persistence (hours) and rapid erasure (seconds). As published in a recent Nature paper, the University of Arizona team has… more
Abstract:The primary objective of this program is to develop a compact, low cost, waveguide optical isolator that can be readily integrated with a large range of photonic integrated circuit (PIC) technologies including semiconductors, glass and polymers operating between 830nm and 1500nm wavelengths. The… more
Abstract:As the power demands of airborne sensor platforms increase there is a growing need for improved capacitor technologies for compact energy storage. While progress has been made on electrolytic supercapacitors as well as nanocomposite composites, an ultrahigh dielectric strength capacitor with high… more
Abstract:This project will develop an energy saving manufacturing process for fuel nozzles, which will result in materials and fuel economy, reduced fabrication costs, enhanced fuel efficiency, and lower air pollution. The proposed process eliminates the machining of the nozzle bodies and the… more
Abstract:DESCRIPTION (provided by applicant): Numerical Tools for analyzing cell signaling circuits in normal and tumor cells The proposal, part I of a phased STTR award, describes the development of software tools, workflow and proof-of-principle case studies for
detailed kinetic modeling of cell signaling… more
Abstract:We propose the development of a validated analysis tool to predict damage growth and useful life of loaded fastener holes in laminated composites. The objectives of Phase I are (1) to develop and verify a concept for comprehensive damage initiation and growth models applicable to loaded fastener… more
Abstract:In order to increase efficiency, modern propulsion systems are required to operate at significantly higher temperatures than in the past. An increased heat load is therefore placed on the fuel that is used as a coolant and on the engine lubrication system. Lubricating oils are typically limited to… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project concerns the design, development and commercialization of systems for real-time measurement and enhancement of the quality of video distributed over emerging networks. The Phase I project has demonstrated the feasibility of a real-time… more
Abstract:Active phased array radars are expensive and solid state power and low noise amplifiers are a major component of that expense. Sharing these amplifiers amongst many antenna elements is a strategy for reducing expense. However, in order to maintain independent phase control, the phase shifter and its… more
Abstract:DESCRIPTION (provided by applicant): Transporters are a class of more than 300 membrane proteins that regulate how nutrients and drugs enter and leave biological cells. Transporters have validated clinical significance and affect every aspect of drug ADMET
(Absorption, Distribution, Metabolism,… more
Abstract:Electronic procedures are currently being used to document the steps in performing medical operations for the Space Shuttle and/or the International Space Station (ISS). Capturing the data electronically makes is easier to manage, modify and query the contents of the procedures. For the ISS, NASA is… more
Abstract:NASA captures and distributes operational knowledge in the form of procedures. These procedures are created and accessed by a range of people performing many different jobs. These people have different needs for procedure data and different ways of interacting with procedures. We propose an… more
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