Abstract:DESCRIPTION (provided by applicant): SBIR grant support is being sought by 20/20 GeneSystems, Inc. (20/20), a small biotech company, to help us advance what we believe will become the first blood test to be routinely employed to aid in the early detection
of head and neck cancer. Despite recent… more
Abstract:DESCRIPTION (provided by applicant): Approximately 135,000 new cases of non-small cell lung cancer (NSCLC) are diagnosed each year in the USA, yet only 20%-25% of those patients will be diagnosed at a sufficiently early stage to be cured by surgical or oth
er procedures. When used in concert with… more
Abstract:Zybek Advanced Products has proven the ability to produce industrial quantities of lunar simulant materials, including glass, agglutinate and melt breccias. These are critical components in the NU-LHT-series and OB1 lunar simulants. The feed stock for this simulant is a mining industry by-product.… more
Abstract:This Small Business Innovation Research (SBIR) Phase II seeks to develop a surface texturing technique that will significantly improve sunlight coupling into various types of solar cells. Surface textures are mandatory to record efficiencies in solar cells. The Omni-Directional Antireflective… more
Abstract:In typical, multi-organizational networking environments, it is difficult to define and maintain a uniform authentication scheme that provides users with easy access to required information while maintaining the security and integrity of the underlying information. This proposal offers a unique and… more
Abstract:DESCRIPTION (provided by applicant): The goal of the present work is to demonstrate a label-free multiplexed immunoassay platform liver disease diagnosis. The method is to integrate multiple tests for serum antigens and antibodies onto a single disposable
chip that could be used with the instrument… more
Abstract:DESCRIPTION (provided by applicant): We propose the development of a single-chip, multiplexed, label-free platform for Alzheimer's disease diagnosis and monitoring of protein markers in the cerebral spinal fluid (CSF). The Spectral Reflectance Imaging Bio
sensor is a label-free protein array… more
Abstract:DESCRIPTION (provided by applicant): Important advances have been made in the treatment of viral infections over the last two decades, especially with the extensive availability of drugs to treat HIV infection, but there is a need to develop new drugs part
icularly with the challenges facing HIV… more
Abstract:Memory overwriting vulnerabilities (buffer overflow, format string,
double free, integer overflow, etc.) continue to plague commercial and government software, providing avenues for attackers to gain unauthorized control over computer systems. Testing tools are needed that will find vulnerabilities… more
Abstract:Many software defenses against reverse engineering, piracy, and tampering rely on disabling the software when such attacks are detected. The proposed research makes innovative use of proces-level software virtualization on a per-application basis to defeat such attacks without disabling the software… more
Abstract:DESCRIPTION (provided by applicant): Our aim is to discover novel safety assessment candidates (pre-clinical compounds) for the treatment of cancer by targeting the receptor tyrosine kinase (RTK), anaplastic lymphoma kinase (ALK). It is now proven that ALK
has a widespread pathogenic involvement in… more
Abstract:This Small Business Innovation Research Phase I project seeks to demonstrate the high-density feasibility of a novel memory, which has both volatile and non-volatile functionality. Such memory combines the non-volatile memory's ability to retain information in the absence of power (such as Flash… more
Abstract:The objective of the proposed effort is to demonstrate the feasibility of the scalable 3D display technology proposed by Zebra Imaging to produce realistic auto-viewable 3D images for Air Force applications related to air, space and cyberspace. A display producing such holographic images can provide… more
Abstract:This SBIR Phase I research proposal will develop nano-porous carbide-derived carbon electrodes for improved super-capacitor performance. The high power charge/discharge rate of current super-capacitors is offset by a low storage capacity compared to batteries. The capacitance of activated carbon… more
Abstract:This proposal presents a Phase I SBIR project to develop high-energy, high-power supercapacitor-battery hybrid energy storage systems. Batteries are widely used, but have limited power capability and cycle life. Supercapacitors, also called ultracapacitors or double-layer capacitors, are… more
Abstract:Crisis decision-making is difficult and error-prone because it involves time-urgency, physical and emotional stress, chaotic conditions, and poor data availability/quality. This SBIR project will investigate, develop, and deploy a web-based software system (called PolARES) that supports key… more
Abstract:This Phase II SBIR project will provide real time, relative six Degree of Freedom (6DoF) information to the crew of the ORION for docking. Our technical innovation performs optimized correlation (ULTORREG), using video from the centerline (boresight) camera, to accurately locate features… more
Abstract:One of the challenges of helicopter cargo missions is dealing with external slung loads. During flight, these loads often move in complex ways driven by forces generated by atmospheric effects and the helicopter's downwash. A low-cost, accurate and airworthy system for measuring the load's motion… more
Abstract:This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This Small Business Technology Transfer Phase I project will address the problem of a multifunctional wide band-gap aluminum gallium nitride single crystal substrate that will enable low-defect,… more
Abstract:This Small Business Innovative Research Phase I project is to develop a commercial growth process for single crystals of KBe2BO3F2 (KBBF) using hydrothermal techniques. KBBF shows exceptional promise as a deep UV non-linear optical material (NLO). NLOs are vital for the development of solid-state… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project aims to develop a low-cost, easy-to-use, image sensing attachment for standard microscopes that provides phase imaging capabilities. The functionality of the bulk optics typically required for such a specialized microscopy technique is… more
Abstract:In this Phase I STTR program teaming with magnetic and materials experts Advanced Powder Solutions will develop a low cost high strength, high tensile, nano-structured soft magnetic alloy and rapid fabrication of magnetic component for actuators using innovative consolidation process. Teaming with… more
Abstract:Novel materials will be needed to help all programs within the DoD. The objective of this Phase I is to demonstrate multi-functional composites that are low cost and lightweight for multiple applications. Phase I will be about fabrication and characterization of the lightweight materials. APS has… more
Abstract:Understanding that saving weight without sacrificing performance on a vehicle is important, the objective of this program is to continue to demonstrate advanced lightweight materials that can have multi-functional capability and be discretely made into parts for DLA. Many applications will have… more
Abstract:The Energy Policy Act (EPACT) of 2005 mandated that the U.S. Department of Energy (DOE) shall establish a ¿Next Generation Nuclear Plant¿ (NGNP) project. For this project, the DOE elected the Very High Temperature Reactor (VHTR) design as a concept that will demonstrate the production of both… more
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