Abstract:Breast cancer is a devastating affliction in Western Society. It is of high interest to quantify the expression of HER2/neu (a growth factor receptor), the estrogen receptor (ER), and the progesterone receptor (PR) in breast cancer tumors since HER2/neu expression is associated with… more
Abstract:The overall objective of this proposal is to preclinically develop VMD-1201 or a lead analog compound of a preferentially peripheral-acting PKC epsilon inhibitor as an oral targeted anticancer drug for treatment of human head and neck cancer with much reduced side effects. The long term goal of… more
Abstract:DESCRIPTION (provided by applicant): The purpose of this SBIR project is to develop a new tool to improve the ability of blind and visually impaired people to quickly get to the right web pages, to avoid ending up on the wrong web pages, and to reach the d
esired part of the web page efficiently.… more
Abstract:DESCRIPTION (provided by applicant): Freezing of Gait (FOG) effects the majority of the approximately one million individuals who have Parkinson's disease nationwide and causes a cessation of movement that patients describe as feeling as if their feet areglued to the ground . FOG most often… more
Abstract:This Small Business Technology Transfer (STTR) Phase II project will advance the development and prototype testing necessary to transition an innovative large scale generating system from concept to commercialization. The underwater energy generation system is based on the naturally occurring… more
Abstract:Military applications for the use of directed electromagnetic energy, which include high power microwave (HPM), seek to disrupt electronic systems by exploiting non-linearity in semiconductors. While current mode second breakdown is a thermal non-linearity often exploited, it has been demonstrated… more
Abstract:Voss Scientific proposes an innovative methodology to determine the susceptibility of electronic systems to electromagnetic interference. Termed the Automated Susceptibility Test Architecture (ASTA), this novel adaptive approach will result in decreased test times and potentially discover unique… more
Abstract:There is a strong need to develop inexpensive and efficient pretreatment processes which can be used by the biofuel industry to make it economically viable. The process of converting to useful liquid fuel lignocellulosic biomass, which is available in abundant quantity, is hindered by the… more
Abstract:There is a need for a high-resolution two-dimensional focal plane array (FPA) with single photon sensitivity (SPS), pulse amplitude storage, and GHz bit rates that can record both the time (with 10 bits) from multiple returns from a single laser pulse. Such a system… more
Abstract:New, modular radiation hard [>300 kRad (Si)] ROIC designs are required to address the needs of planned ballistic missile defense system. Anticipating the needs for large formats, small pixel sizes, and multiple spectral bands, the features of an existing radiation-hard space imager ROIC will be used… more
Abstract:Future seekers of the future will need to allow for multiple targets and various advanced countermeasures, likely including a dual-mode component to do so. A Dual Mode Seeker (DMS) has at least an infrared (IR) Focal Plane Array (FPA) as well as an active means to capture target range and preferably… more
Abstract:A back-illuminated planar InGaAs photodiode tested to have 95% quantum effiiency (QE) at 1550 nm, area greater than 1 mm2, low capacitance (<23 pF), and high bandwidth (>125 MHz) will be improved. Although the existing Phase I device exhibited bulk material dark current generation better… more
Abstract:The capacity to integrate RF and free-space optical hybrid communications is now feasible given advances in adaptive optics and optical automated gain control. Proposed is a novel high-speed avalanche photodiode (APD) receiver, with over 5 GBPS data rates, and single-photon sensitivity. The APD… more
Abstract:Visible-transparent upconverting films consisting of lanthanide-doped metal-oxide nanocrystal (NC) quantum dots functionalized with near-infrared (NIR) and short-wavelength infrared (SWIR) sensitizers will be optimized for integration with polycarbonate optical elements. In Phase I, upconversion was… more
Abstract:A 128 x 128-format avalanche photodiode (APD) focal plane array (FPA), including a low-power dual-mode readout integrated circuit (ROIC) and low excess noise, high gain (M>1,200) will be developed for laser radar (LADAR) applications requiring reduced SWAP. The FPA gives LADAR seekers an advanced… more
Abstract:Current methods of growing carbon nanotubes (CNTs) of specific chirality yield mixtures of single-walled CNTs (SWNTs) with different structures and electronic properties, and methods to separate nanotubes by their electronic properties remain expensive and small-scale. Accordingly, synthesis today… more
Abstract:There is a need for technologies that protect the health and welfare of the American people in a terrorist emergency by detecting acts of biological contamination. Of the chemical, biological, and explosive (CBE) agents, anthrax, smallpox, plague, ricin, botulinum toxin, toxic commercial… more
Abstract:For detection and neutralization of mines and other threats in the surf zone (SZ), a 3D imaging system will be developed with higher resolution and greater sensitivity than contemporary designs. Using circuits proven on existing designs, the readout integrated circuits (ROIC) of a small-pixel-size… more
Abstract:90087S09-II Expanding user demand for X-ray beamline time for science experiments in diverse fields necessitates expensive new beamlines, or the more efficient use of existing resources. Detectors that collect more data, with efficient on-chip and off-chip processing of the resulting data streams,… more
Abstract:Direct detector materials must exhibit several attributes including both good photon absorption properties and high charge collection, as well as low dark current and good uniformity. These are difficult to achieve in a single material. So far no photoconductor material has been found with… more
Abstract:The X-ray science community has recognized an urgent need for developing advanced X-ray detectors to utilize the full potential offered by the third generation X-ray synchrotron facilities, with particular emphasis on tailoring performance to meet beamline science needs. The ability of modern… more
Abstract:Large-scale physics experiments often use conventional analog pulse-processing techniques that require multiple instruments such as a pulse shaper, multi-channel analyzer, time-to-amplitude converter, and analog-to-digital converter. For accurate energy resolution and noise immunity using this… more
Abstract:Currently there are no CMOS imaging foundries available, especially domestic, which offer services that provide the high performance required for charge coupled imaging. As wafer sizes increase and feature sizes decrease, the cost of prototyping a science grade imager can easily exceed $0.25M.… more
Abstract:During the Phase I period, we have successfully developed and demonstrated all the major technical components to achieve the goal of providing seamless large scale display anywhere, anytime, for any content. Based on the solid foundation we have built from Phase I, we plan to improve and integrate… more
There are several categories such as “By Agency”, “By Year”, “By State” etc.
Select a checkbox within a category to refine your search results.
Each of your selections is listed in the “Narrow Search Filters” bar. You can uncheck these selections to remove them.
Search for Either Criteria
When you select multiple values within a category, the results will include values that match either of the selections.
For example, selecting “2005” and “2007” in the “By Year” category will display results that include either 2005 OR 2007 in the results.
Narrowing the Search Results
You can refine your search results across categories. To narrow down your results, select multiple values across different categories. The results will only include values that match the selections across the categories.
For example, selecting “2005” in the “By Year” category and “NASA” in the “By Agency” category will only display the results that contain both “2005” AND “NASA” in the results.