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Year:2010
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Displaying 7051 – 7075 of 7100 Awards
Company: ODYSSEY SCIENCE INNOVATIONS, LLC Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Over 7.5 million high school students participate in high school sports programs and an additional 2 million students join these athletic teams each year. Adolescent athletes are at risk for using performance enhancingdrugs, such as anabolic steroids, unregulated… more
Company: GRIFFIN LABORATORIES, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): The most common artificial voice source for post-laryngectomy speech rehabilitation is the hand-held buzzer or electrolarynx (EL). This device is relatively easy to use and enables most laryngectomees to verbally communicate, but with reduced intelligibility and… more
Company: 3DMD, LLC Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): The primary goal of this Fast Track STTR application is to develop a 4D facial analysis system for both static and dynamic analyses that will utilize high resolution 3D cameras to acquire patient-specific facial shape information along with software that will be… more
Company: APOVAX, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Pancreatic islet transplantation is a viable approach for the treatment of type 1 diabetes (T1D). However, this therapeutic approach suffers from graft rejection. Dr. Shirwan, founder of ApoImmune, has developed a novel immunotherapeutic approach aimed at… more
Company: HYGIEIA RESEARCH, LLC Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Diabetes has become a growing epidemic, yet treatment goals are seldom achieved, and patients endure detrimental complications. Insulin is the only dose-dependent antidiabetic medication in which most patients can accomplish balanced blood glucose levels when… more
Company: Medical Nanotechnologies, Inc. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): The Environmental Protection Agency (EPA) recently classified carbon nanotubes (CNTs) as a new chemical substance. Consequently, CNTs are now subject to regulatory controls that require inventory control, quantificationof CNT amounts, and possibly toxicity tests.… more
Company: SYNTHIA, LLC Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Polybrominated diphenyl ethers (PBDEs) are common flame retardants used to reduce the risk of fire in a wide variety of products, such as mattresses, furniture, home electronics, textiles, upholstery fabrics, carpet, and children's toys. As a consequence,… more
Company: NANOTRANS TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Age Related Macular Degeneration (AMD) is the leading cause of blindness in adults over 50 years. Choroidal neovascularization (CNV), the pathologic creation of new blood vessels in the choroid layer of the eye, is a principal cause of blindness due to AMD.… more
Company: LUCELLA BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): The synthesis of carbohydrates remains a complex exercise that involves tremendous labor and large amounts of expensive building blocks and reagents. Even once a process for making a carbohydrate has been developed, manufacture of that molecule in all the… more
Company: BIOINFORMATICA, LLC Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): The advent of target-based drug discovery, assisted by advances in x-ray crystallography and NMR, has left pharmaceutical companies suffering both from too much and too little information: too much information in the sense that the early push for target discovery… more
Company: SOLUBLE THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): This proposal involves the development and validation of a novel approach to improve and accelerate the discovery of biopharmaceuticals (i.e. vaccines, monoclonal antibodies and other therapeutic proteins). Biopharmaceuticals are used to treat a variety of… more
Company: ANIMA CELL METROLOGY, INC Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): As technologies of gene and protein cataloging are maturing, the study of cellular dynamics is becoming the next frontier in biological research. New technologies are required to capture the complexity of cellular dynamics. Against this background we propose the… more
Company: MOLECULAR SENSING, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Molecular interactions are central to the understanding of basic biology and cellular function, are paramount to all molecular assays (research and in vitro diagnostics), are essential in biomarker discovery and critical toward evaluating therapeutics. However,… more
Company: VYBION, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): With over 300 therapeutic proteins currently in various stages of clinical trials, the road to a healthier future will require new methods for producing safer and less expensive recombinant proteins. In particular, nextgeneration therapeutics derived from… more
Company: Canton Biotechnologies Inc Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Therapy to Improve Wound Healing with DNA Expression Vector for HIF 11 and Electroporation Impaired wound healing is a tremendous problem for individuals with diabetes. Patients with diabetes are at risk for developingfoot ulcers. These non-healing ulcerations on… more
Company: SENA RESEARCH, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): There are growing demands for 3D structure determination of nucleic acids and protein-nucleic acid complexes for understanding disease molecule-level mechanisms and discovering new drugs. X-ray crystallography is one ofthe most direct and powerful tools for… more
Company: RAYBIOTECH, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Protein and antibody arrays have emerged as a technology to study protein expression and protein function in a high throughput manner. RayBiotech, Inc., as a protein array pioneer company, has developed many unique protein and antibody array technologies and… more
Company: BIOCAX, LLC Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Precise 3-Dimensinal (3D) measurement of human body is essential for prostheses and orthoses design and manufacturing. Traditionally, plaster bandage was used for molding and producing negative mold of the residual limb. It is a laborious, time-consuming, and… more
Company: ACTIVE WAVE, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Evidence and theory indicate that laboratory measures of impairment and function do not predict how older adults actually function in daily life. Thomas Glass (1998), for example, reports marked differences between functional activities that community residents … more
Company: ARGINETIX, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): The product that will result from this STTR is ABH (2(S)-amino-6-boronohexanoic acid), a potent small molecule inhibitor of the enzyme arginase, for treating vascular complications of diabetes. There are 20.8 million Americans with diabetes. More than 65% of… more
Company: RIMEDION, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): HIV-1 based lentiviral vectors are becoming an increasingly attractive means of integrating transgenes into target cells. Vectors are in or enterning clinical trials for a diverse group of ailments, including genetic disease, AIDS and cancer. Rimedion and its… more
Company: RIMEDION, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): HIV-1 based lentiviral vectors are becoming an increasingly attractive means of integrating transgenes into target cells. Vectors are in or enterning clinical trials for a diverse group of ailments, including genetic disease, AIDS and cancer. To expand the range… more
Company: NONINVASIX, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Assessment and management of circulatory shock in critically ill patients requires rapid measurement of two critical variables: mixed venous oxyhemoglobin saturation (venous SO2) and total blood hemoglobin concentration[Hgb] to identify insufficient oxygen… more
Company: CARDIOFOCUS, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): The objective of this project is to develop a system to optically record fluorescence signals from heart tissues in vivo. Fluorescent dyes have been used to record biological processes from the heart for more than a decade. Specifically, staining the heart with… more
Company: REVERAGEN BIOPHARMA, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Asthma is a very common lung condition in children, and incidence is increasing in the US particularly in urban and minority populations. The standard of care for asthmatics is inhaled steroid, although clinical response is variable. The mechanism of efficacy of… more
Displaying 7051 – 7075 of 7100 Awards
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