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Year:2010
Company: CORGENIX MEDICAL CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Viral hemorrhagic fevers (VHFs) are serious, often fatal, illnesses characterized by high fever, damage to the vascular system and multiorgan failure. Our team has successfully produced prototype Lassa virus ELISA that
are based on recombinant proteins rather… more
Company: ALTRAVAX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): The HIV-1 epidemic has resulted in ~2.7 million new infections in 2007 for a total of ~33 million people living with HIV/AIDS. Clinical trials have shown that HIV-1 infection cannot be prevented by immunization with mon
omeric recombinant forms of viral envelope… more
Company: ALTRAVAX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Influenza is a major cause of morbidity and mortality around the world. In the United States, seasonal epidemics of flu occur from late fall to early spring affecting all age groups but with especially high rates of in
fection in children. Serious illness and… more
Company: ALTRAVAX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): The HIV-1 epidemic has resulted in ~2.7 million new infections in 2007 for a total of ~33 million people living with HIV/AIDS. Clinical trials have shown that HIV-1 infection cannot be prevented by immunization with mon
omeric recombinant forms of viral envelope… more
Company: PAXVAX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Development of a vaccine to prevent, or reduce the rate of, HIV infections remains a high priority despite recent setbacks in the field. The lessons from failed and successful experimental programs indicate the need to
apply new approaches to HIV vaccine design… more
Company: TRIM-EDICINE, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Defective membrane repair is associated with the progression of muscular dystrophy that is linked to mutations in caveolin-3 (Cav3) and dysferlin in human patients. Several other forms of muscular dystrophy, including D
uchenne muscular dystrophy and dystrophy… more
Company: FIT INTERACTIVE, LLC Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): A universal dilemma faced by family and friends (care network) of a person with dementia (PWD) is how to effectively communicate, interact, and psycho-socially connect with the PWD as the dementia progresses and their a
bilities decline. Communication… more
Company: BIOSCAN, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): The overall goal of this application is to develop a quantitative in-vivo small animal imaging system for fluorescent reporter probes that fuses fluorescence light emitting computed tomography (FLECT) with X- ray comput
ed tomography (CT). The proposed… more
Company: APTAKON, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Identifying the regulatory regions of the genome is critical for understanding the regulatory networks underlying human development and disease. Chromatin immunoprecipitation (ChIP) coupled with microarray (ChIP-chip)
or sequencing (ChIP- seq) is a widely used… more
Company: APTAKON, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: Many of the antibodies produced for cancer research are poorly characterized, exhibit suboptimal affinity or selectivity, and are time-consuming and expensive to produce. Alternative affinity capture reagents are therefore needed as reproducible, highly characterized, rapid, and cost-effective… more
Company: TELESAGE RESEARCH, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): With funding from NIMH, TeleSage has developed a state-of-the-art mental health outcomes tracking survey instrument for use with both public- and private-sector adults. This survey is currently in statewide use in Tenne
ssee and Iowa. Unfortunately, no… more
Company: TELESAGE RESEARCH, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 2
Abstract: DESCRIPTION (provided by applicant): Computer Adaptive Testing (CAT) provides a new mechanism for assessing patient-reported outcomes. Using CAT can: (a) increase measurement precision, leading to a decrease in the number of participants necessary to achieve statistically significant… more
Company: QUANTUM MEDICAL METRICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): Rheumatoid Arthritis (RA) is a debilitating disease which affects nearly 1% of the US population. It initially attacks the small joints of the hand and foot. Recent RA research shows that early aggressive therapy is mos
t effective, making early diagnosis… more
Company: Ultracor Agency/Program/Year/Phase: NASA / SBIR / 2010 / 1
Abstract: The proposed project is to manufacture a C-SiC honeycomb structure to use as a high temperature material in advanced aircraft, spacecraft and industrial applications. The proposers will fabricate a carbon fiber honeycomb structure. The structure will be charred and then converted to C-SiC by means… more
Company: SIMPORE, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): In this Phase I application we will examine the feasibility of producing high yield porous nanocrystalline silicon (pnc-Si) membranes for protein purification products. Membranes made of this material are a breakthrough
technology, 1000x thinner than… more
Company: ELORET Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: Performance of conventional primary and secondary batteries improve at a meager rate every year. Sensors and sensor networks which are advancing through relentless miniaturization effects need uninterrupted power sources in many scenarios. We propose to use a piezoelectric based energy scavenging… more
Company: ELORET Agency/Program/Year/Phase: NASA / SBIR / 2010 / 1
Abstract: ELORET Corporation, in collaboration with the Space Systems Design Laboratory of Georgia Institute of Technology, proposes developing and demonstrating a capability/technology to de-orbit small payloads (approximately 1 kg) from Low-Earth Orbit and returning them to Earth safely. To achieve this… more
Company: HARP Engineering LLC Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: The proposed phase I research effort will develop a highly efficient MEMS energy harvesters that utilize a novel nanocomposite technology recently developed by Sodano Engineering LLC. Unlike existing piezoelectric nanocomposites, the material proposed here has an electromechanical coupling… more
Company: HARP Engineering LLC Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: The proposed Phase I research effort will develop a novel technique to place vertically aligned ZnO nanowires in the interlaminar region of fiber reinforced composites. It is widely accepted that the interlaminar region of a composite presents one of the most challenging failure mechanisms to… more
Company: BNOAT ONCOLOGY, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: Oncology remains a major market of unmet need. BNOAT Oncology¿s long-term objective is New Drug Approval of its lead candidate nitrosylcobalamin, a tumor-specific, apoptosis-inducing, anti-cancer drug. Research Design and Methods: Nitrosylcobalamin purification will include… more
Company: RAM Photonics Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: Rapid tuning of narrowband sources is inherently limited by the number of roundtrips required in the high-Q cavity, which is required for generation of a narrow lasing linewidth. We propose to break the cavity tuning/linewidth barrier presented by conventional reconfiguration of the physical cavity… more
Company: RAM Photonics Agency/Program/Year/Phase: DOD / SBIR / 2010 / 1
Abstract: Advanced airframes are expected to serve in multirole missions; mission-specific nodes must be incorporated in a scalable manner without performance penalty to existing services. Such systems are expected to operate with a mix of digital and analog signaling, with certain nodes likely requiring… more
Company: TUNITAS THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): The overall goal of this SBIR proposal is to develop and commercialize a new approach for allergen specific immunotherapy as treatment for cat allergy. This proposal will provide a novel therapeutic for a very importan
t inhalant allergen and serve as a model… more
Company: TUNITAS THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / STTR / 2010 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this proposal is to develop and commercialize a novel approach for allergen specific immunotherapy as treatment for severe food allergy. Food allergy affects about 3.5% of the US population and 6% to 8% ofyoung children. It is clearly on the rise.… more
Company: Astrobotic Technology, Inc. Agency/Program/Year/Phase: NASA / SBIR / 2010 / 1
Abstract: Robust, lightweight, power-efficient excavation robots are mission
enablers for lunar outposts and surface systems. Lunar excavators of this
type cost-effectively utilize native materials for both outpost
preparation and in-situ resource utilization. They address the need for
implements that dig,… more
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