Abstract:DESCRIPTION (provided by applicant): Over 90% of cancer patients that enroll in Phase I or II clinical trials experience no benefit from the experimental therapies, yet are exposed to drug toxicity and other challenges related to treatment. For over 50 years, physicians have used patient-specific… more
Abstract:DESCRIPTION (provided by applicant): There is a significant unmet medical need to provide additional pharmacologic treatments for treatment and prevention of opioid overdose. This Fast Track STTR project proposes to apply drug delivery technologies to develop a novel use for a nasally delivered… more
Abstract:DESCRIPTION (provided by applicant): This project aims to develop a commercial software product, VirtualDoseTM, for calculating and analyzing patient radiation doses from x-ray computed tomography (CT) examinations. Despite its essential role in radiology, CT is responsible for raising the… more
Abstract:DESCRIPTION (provided by applicant): A major cause of morbidity and mortality in cardiovascular surgery is excessive bleeding post- operatively, which is commonly managed by pharmacologically modifying clot degradation (fibrinolysis), through inhibition of plasmin activity (PLact). However, the only… more
Abstract:Background Information Rituxan and Herceptin are multi-billion dollar products that are useful in lymphoma and breast cancer. However, significant unmet medical need persists for certain populations such as recurrent indolent NHL, HER2 IHC 2+ patients, and treatment of patients with the FcgR3a 158… more
Abstract:Under this SBIR Phase II project, the Contractor shall develop and evaluate their " Clinical Trial Participant Management System." This product will be comprehensive, integrated IVR phone and Web (email and text) delivered database system designed to facilitate the management of clinical… more
Abstract:Alcohol abuse and its related health effects are estimated to have an economic cost in the US that approaches $200 Billion per year. However, current tests for alcohol use/abuse are not reliable except when administered within several hours of intoxication. Moreover, current clinical tests for… more
Abstract:Develop a repository of human cardiovascular and cardiopulmonary computer models consisting of realistic, image-based anatomic models of large arteries and airways, generic, distal vascular beds, and representative blood and tissue properties. Simulationsbased on repository data will have… more
Abstract:SID Technologies is developing intradermal devices aiding healthcare workers in performing intradermal injections. The goal is to provide an alternative, easier to learn method of intradermal drug delivery to the Mantoux technique, in order to expand the population of healthcare workers who may… more
Abstract:Resource optimization strategies for engaging multi-stage, long-range missiles carrying multiple warheads during the ascent phase is an area of interest to MDA and the larger DoD community. The ability to rapidly predict the outcomes of extremely large numbers of decision permutations is crucial in… more
Abstract:This SBIR Phase II proposal to the Department of Defense, Army, requests funding for Innova Dynamics to optimize and scale up the Innlay-based IonArmour Next Generation technology for deployment, providing the highest levels of safe, cost-effective, continuous antimicrobial protection for military… more
Abstract:The proposed Phase II effort involves development and demonstration of an all-carbon fiber/epoxy aft shell body and integrated aft pusher assembly for gun launched hypervelocity applications. The all-carbon fiber technology is the selected approach for this effort, owing to the cost effectiveness,… more
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