Abstract:Next generation lasers for Missile Defense ranging applications require scaling pulse brightness and repetition rates in compact and efficient packages. To address this need, nLIGHT proposes to significantly increase the pulse energy of a passively Q-switched diode pumped solid state laser while… more
Abstract:U.S. security is increasingly concerned with the threat posed by small non-governmental groups
which are capable of and dedicated to inflicting harm on U.S. citizens, their property and their
way of life. The weapon of choice for such groups is the Improvised Explosive Device (IED), a
threat which… more
Abstract:ABSTRACT: The key objective of the proposal is to develop sophisticated, graphical user interface driven software tools built on fully microscopic physics to design, guide and provide feedback on growth, fabrication and evaluation of semiconductor structures that provide optical gain in the… more
Abstract:ABSTRACT: The Air Force Flight Test Center (AFFTC) is interested in upgrading their test aircraft fleet (or a portion thereof) to have onboard smart sensors (OSS). The target SBIR product for this project is a set of hardware components that allows the integration of IEEE 1451.4 Smart Sensors into… more
Abstract:ABSTRACT: Norconnect, Inc. proposes to develop a unique digital flight glove electronic system which will i) record electromyographic (EMG) signals generated by hand muscles of a pilot or a flight engineer when they move their fingers or hands in the air, ii) recognize recorded EMG signals with… more
Abstract:Coordinate Registration (CR) of OTHR targets requires accurate real-time ionospheric modeling coupled with HF propagation calculations to convert radar-measured target signal delays and beam steers to geographical position. Our team is the developer of the most sophisticated CR capability currently… more
Abstract:ABSTRACT: Over-the-Horizon radar (OTHR) uses ionospheric reflection to propagate HF transmissions to long range (~500-5000 km). The ionosphere is a dynamic"mirror"that varies diurnally, seasonally, and with the solar cycle. Geolocation of targets observed by OTHR, (Coordinate… more
Abstract:DESCRIPTION (provided by applicant): Me, A Doc is a serious medical diagnosis role-playing simulator program in a video game interface that aims to improve high school and college student learning about the biology of disease in a way that fosters critical thinking and reduces the achievement gap… more
Abstract:NOVA Scientific, Inc., teamed with the Electronics Group of Oak Ridge National Laboratory, proposes to construct very large area Microchannel Plate neutron detectors. The applications of these much larger format detectors will serve an exceptionally broad range of government agencies from neutron… more
Abstract:There is an urgent need for an effective chemical-free control measure for crown gall. Crown gall is a major disease of many perennial crops. It is especially a problem in long-lived woody crops such as roses, where galls on rose bushes render plants unsalable. In the case of woody fruit and nut… more
Abstract:DESCRIPTION (provided by applicant): The clinical significance of chronic pro-inflammatory reactions in dialysis patients due to exposure to endotoxin has become a central issue in nephrology. The European Renal Association urges the routine use of ultrapure dialysate with bacteria and endotoxin… more
Abstract:DESCRIPTION (provided by applicant): Staphylococcus aureus is the second leading cause of hospital-acquired bloodstream infections. In 2003, nearly 300,000 patients in US hospitals acquired an S. aureus infection, which accounted for nearly three million days of hospitalization, 9.5 billion in… more
Abstract:DESCRIPTION (provided by applicant): Approximately 24 million adults and children in the United States have 1 Diabetes Mellitus (diabetes) and 1.6 million new cases are diagnosed each year. Type 2 is the most common form of the disease accounting for over90% of the diabetics worldwide. The remaining… more
Abstract:Under battlefield conditions, warfighters face a wide range of cutaneous injuries, many of which are susceptible to life- and limb-threatening microbial infections caused by multi-drug resistant bacteria. Nitric oxide is a powerful, broad spectrum antimicrobial agent that is naturally produced by… more
Abstract:The number of distinct malware being released into the wild is growing at an alarming rate. Some IT security companies are seeing more than 5,000 new malware instances each day. IT security companies can no longer keep pace with this deluge using manual, labor-intensive malware analysis techniques… more
Abstract:DESCRIPTION (provided by applicant): Over the past several decades there has been relatively little innovation in the arena of medical device sterilization. Ethylene oxide (ETO) and gamma irradiation (3-irradiation) are the only technologies currently available for medical devices. In particular,… more
Abstract:DESCRIPTION (provided by applicant): Nearly 70 million people in the US suffer from arthritis related conditions[1, 2]. Of these, rheumatoid arthritis (RA) cases constitute approximately 3 million. RA is a chronic systemic inflammatory disease that primarily results in erosive destruction of… more
Abstract:DESCRIPTION (provided by applicant): NovelMed's lead drug candidate prevents biomaterials induced cellular activation. Activated cells release inflammatory mediators that are responsible for pathological trauma that leads to cardiac, lung, liver, and braininjuries during surgical procedures… more
Abstract:DESCRIPTION (provided by applicant): Artificial surfaces of cardiac devices induce cellular activation and platelet dysfunction in patients undergoing bypass procedure. While other pathways may be activated during this process, alternative pathway (AP) activation appears to be one of the important… more
Abstract:This proposal is for the development of an innovative, high power, and extremely reliable 1.26-micron Ho-doped fluoride fiber amplifier. The proposed fiber amplifier consists of a Ho-doped fluoride fiber pre-amplifier and power amplifier. Laser at 1187 nm will be used as a resonant pump laser… more
Abstract:We propose an all-fiber based 2.05-micron single frequency, narrow linewidth seeder laser with 10 nm tuning range and 5GHz frequency modulation for next generation LIDAR system. Highly Tm-doped fiber laser is used as a resonant pump source in order to reduce the phase noise and laser linewidth. An… more
Abstract:For NASA's various types of coherent LIDAR applications, NP Photonics propose to develop a 50 mJ monolithic 2 micron pulsed fiber laser transmitter in 200 ns regime with transform-limited linewidth, leveraging on NP's proprietary germanate active fibers. NP's patented large core SM PM… more
Abstract:NP Photonics proposes to develop an ultra-stable, compact, and highly reliable deep ultraviolet (UV) laser source for Raman spectroscopy. For this, we will draw on NP Photonics"long experience with the commercialization of single-frequency fiber lasers and amplifiers. In cooperation with the… more
Abstract:ABSTRACT: We propose to develop a light weight, compact, vibration-less and micro-scale cooler for space-mission conditions based on optical refrigeration using an all-fiber approach. Specifically, we will use a Tm+3-doped fiber laser to pump Tm+3-doped glass fibers, which provide the cooling… more
Abstract:We propose to develop numerical methodologies that can be used as alternatives to standard finite-difference time-domain algorithms, and that will offer substantial reductions in numerical complexity (notably CPU-time requirements) without the need to trade-off flexibility for overall robustness. In… more
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