Abstract:DESCRIPTION (provided by applicant): The long-term goal of this project is to develop Poloxamer-188 (P-188) for the delay or prevention of respiratory deficits in patients with Duchenne muscular dystrophy (DMD). Phrixus Pharmaceuticals Inc. is also developing P-188 for the treatment of acute… more
Abstract:DESCRIPTION (provided by applicant): Although conventional sample handling can be adapted for use with processing zebrafish, development of appropriate analytical tools has not kept pace with the increasing use of this animal model for compound screening.In this research, we propose to develop a… more
Abstract:This proposal aims to develop and demonstrate a novel fused sensor system capable of detecting bullets in real time and over a 360o field-of-view. The bullet detection is based on a retrodirective noise-correlating radar that also provides the bullet bearing in real time. The bearing information… more
Abstract:To address this HSARPA need, Physical Optics Corporation (POC) proposes to develop a new Visor-Enhanced SCBA Transparent
Armor (VESTA) lens, based on a transparent metallic-oxide material system, and serving as a drop-in replacement lens in current
mask systems. VESTA possesses improved… more
Abstract:To address the HSARPA need for a next generation helmet with an embedded heads up display for personal situation awareness for emergency
responders, Physical Optics Corporation, POC, proposes to continue the development of the Helmet Embedded Conformal Augmented Display,
HECAD, system. The HECAD… more
Abstract:DESCRIPTION (provided by applicant): It is widely know that if retinopathy and specifically diabetic retinopathy are not duly detected and controlled through medical interventions, they can progress into a proliferative retinopathy and cause significant decrease in… more
Abstract:DESCRIPTION (provided by applicant): Mining accidents are still a regular occurrence, often resulting in the loss of dozens of lives. Many of these fatalities could have been averted had there been a reliable emergency communications system in place to provide life-saving information to… more
Abstract:Current station keeping equipment (SKE) relies on radio waves for formation flying. A significant limitation of conventional SKE signals is that they are detectable at long distances by adversaries. Passive detection schemes that employ infrared and thermal cameras, electro-optic and acoustic… more
Abstract:In this effort, we will couple the energy of focused microwave bursts into the air and onto surfaces by first forming a laser plasma. The presence of the laser plasma allows much lower microwave intensities to couple their energy to the laser-pre-ionized surface or air-volume, allowing more… more
Abstract:ABSTRACT: Piasecki Aircraft proposes to use a variant of its Turais Wing and Bomb Bay Launched UAV (WBBL-UAV) in conjunction with a covert trajectory planner and a guided parafoil to meet the challenges presented in the"Covert Precision Aerial Delivery System"SBIR solicitation. The Turais… more
Abstract:The proposal describes a solution to the challenge presented in SBIR Topic N111-018 for a Low Drag 2.75 Inch Rocket and Advanced Precision Kill Weapon System (APKWS) Launchers. The Phase I approach is to develop and validate through prototype engineering, a Low Drag 2.75"Launcher. PiAC will… more
Abstract:Measurements of 14C or radiocarbon enables fundamental approaches forelucidating the impact of climate and land use change on the carbon cycle including carbon storage and turnover/residence times and the impact of these changes on atmospheric CO2 levels. In addition, in the field of atmospheric… more
Abstract:In this Phase II project, we propose to develop, construct, and deliver to NASA a prototype single-sided computed tomography time-domain terahertz (single-sided CT TD-THz) scanner accessory. This accessory will be suitable to be mounted onto a non-destructive evaluation (NDE) imaging gantry for the… more
Abstract:Picometrix's time-domain terahertz (TD-THz) non-destructive evaluation (NDE) technology could be usedto inspect space flight structures such as inflatable space habitats, thermal protection systems (TUFI-typetiles, SOFI TPS), for voids, disbonds, and damage such as tearing and micron-meteorite… more
Abstract:Pikewerks'Protection for Industrial and Environmental Controls from Exploitation, or PIECE, will be a cross-platform suite of capabilities providing anti-exploitation and anti-reconnaissance for Industrial Control Systems. PIECE will provide a suite of capabilities for Windows, Linux, VxWorks,… more
Abstract:This proposal presents novel approaches for measuring, verifying, and assuring proper digital system configuration. The proposed research combines hardware and software to provide improved verification of trusted system components, including detecting circuit damage, electronic measuring probes and… more
Abstract:Criminal organizations, self-interested individuals, and many foreign militaries employ email-based attacks, referred to as phishing attacks, to deceive individuals into unwittingly divulging private, personal, sensitive, or proprietary information. One of the primary weaknesses in today"s… more
Abstract:Deception Studio (DS) is a learning, behavior-based defense system for ensuring service availability and trust. DS's learning capabilities include attack detection, prediction, and attribution and can react to attacks in real time by shaping an adversary's perception and creating an… more
Abstract:Security in and trust of sensitive information communication has been a critical issue as long as humans have been sending messages, but the increasing reliance on computer networks to transmit sensitive information has brought these matters to the forefront like never before. Old methods of trusted… more
Abstract:With the ongoing involvement of computers in all facets of modern society, both private and public organizations increasingly rely on computer networks to support key portions of their critical infrastructure. Consequently, those networks contain increasingly more sensitive information, making them… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop a Multi-Axis Repair System (MARS), which is an automated precision alignment and repair planner and driver. MARS will make repair processes much more cost-effective and robust. Insufficient automation in current repair… more
Abstract:DESCRIPTION (provided by applicant): Within the last seven years, Drosophila melanogaster or common fruit fly has gained an important niche in becoming an invertebrate model organism for exploring genetic and proteomic mechanisms underlying sleep. While agreat deal of progress has been made in the… more
Abstract:Under Phase I of this SBIR Fast-track project, a base manufacturing process to produce a reliable, robust ethanol biosensor will be developed and the feasibility of the biosensor, capable of real-time monitoring of ethanol, will be demonstrated and a functional prototype ethanol biosensor will be… more
Abstract:The Lunar Organic Waste Reformer (LOWR) utilizes high temperature steam reformation to convert all plastic, paper, and human waste materials into useful gases. In the LOWR, solar thermal concentrators are used to heat steam directly to 600 C, after which the steam is mixed with a small amount of… more
Abstract:Nitrous Oxide Micro Engines (NOME) are a new type of nitrous oxide dissociation thruster designed to generate low levels of thrust that can be used for RCS control in large satellites or as main propulsion in micro-satellites. Nitrous is the ideal propellant choice for RCS control in satellites due… more
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