Abstract:Tuna are among the most highly valued fish worldwide. Due to this value and high demand, tuna are being fished beyond sustainable levels in many parts of the world. Replacing or supplementing wild catch with hatchery raised tuna makes sense, but this is technically difficult with current technology.… more
Abstract:Unmanned vehicles (UVs) are transforming the submarines collection and communication capabilities. However, the user tasks needed to employ UVs are not seamlessly integrated into existing submarine tasks and personnel assignments. Further, submarines will have to flexibly coordinate UV employment… more
Abstract:The primary objective of this proposal is to develop a real-time decision support toolkit to provide mission planners a transparent method for using and interpreting empirical research findings. Such a tool would assist planners in making better educated decisions regarding how various environmental… more
Abstract:The Primed Intuition Training (Prime-IT) program combines cognitive and training science with critical domain knowledge, incorporating advances in immersive training and neurocognitive measurement, to develop the foundation for sound, intuitive decision-making. At the heart of Prime-IT are… more
Abstract:here is great current interest in improving the contact management of submarines operated in the littorals. Littoral contact management is challenging because the ambiguities inherent in contact localization make accurately reconstructing each contact a hard task. Littoral contact density is high,… more
Abstract:Modern warfare takes many forms. A common requirement across this spectrum of conflict is the need to understand and predict combatant and non-combatant goals and actions. OSD directs and oversees the Human Social Culture Behavior Modeling (HSCB) program to develop reliable, validated… more
Abstract:DESCRIPTION (provided by applicant): Loss of hearing affects the quality of life for individuals. The number of Americans with hearing loss is increasing as baby boomers age and younger citizens damage their hearing with personal audio devices. By 2025, approximately 40 million Americans are… more
Abstract:DESCRIPTION (provided by applicant): A Novel Regenerative Therapy for Myocardial Infarction Myocardial infarction (MI) is an acute public health problem killing one third of the 1.5 million Americans afflicted annually. Almost all MIs are caused by ruptureof coronary atherosclerotic plaques with… more
Abstract:DESCRIPTION (provided by applicant): Monobody for Renal Inflammation End stage renal disease (ESRD) affects gt485,000 Americans, including over 341,000 hemodialysis patients with an estimated 90,000 new cases per year. The annual cost of treating Americanssuffering from some form of kidney failure… more
Abstract:DESCRIPTION (provided by applicant): Susceptibility to common human diseases such as cancer and cardiovascular disease is determined by numerous genetic factors that interact in a nonlinear manner in the context of an individual's age and environmental exposure. This complex genetic… more
Abstract:The original Sublimator Driven Coldplate (SDC) design sought to provide significant mass savings over a traditional pumped fluid loop by combining the functions of a cold plate and a sublimator and eliminating the fluid loop (Leimkuehler, et. al., "Design of a Sublimator Driven Coldplate… more
Abstract:Extended duration missions to the Moon and Mars will require the use of In-situ resources to generate propellants and life support consumables. Many of the processes for in-situ resource utilization (ISRU) produce water, along with a variety of acid gases and other water soluble contaminants. … more
Abstract:An inflatable habitat is a pressure vessel with flexible shell. Notable features such as low weight, large inflated operational volume, and small pre-deployment volume offer significant advantages over traditional rigid metallic and composite habitat structures. Conventional designs suffer from… more
Abstract:Paragon Space Development Corporation proposes the use of an microporous-ionomer membrane pair to improve the robustness and effectiveness of membrane-based water separation processes. Improved robustness and effectiveness will be evident through (1) reduced loading on the downstream post processor… more
Abstract:ABSTRACT: The ORS program is designed to field a customizable satellite that can be assembled in a few days. Unfortunately, the TCS is typically custom built around the heat loads and operating environments. For an ORS mission, both the heat load and the operating environments will be unknown… more
Abstract:This Small Business Technology Transfer (STTR) Phase I project will develop the first in a series of theoretically grounded, evidence-based multi-player games designed to address the leading health risk to teens - motor vehicle crashes. This STTR will provide a new model for translating discoveries… more
Abstract:DESCRIPTION (provided by applicant): High Throughput Microrepository for Genetic Materials Recognizing the urgent need for a safe, rapid and reliable means of preserving and archiving genetic samples and other biological materials, such as synthetic DNA samples, unique isolated samples, plasmids,… more
Abstract:DESCRIPTION (provided by applicant): Most cell culture lines are anchorage-dependent and require surface attachment for proliferation. For industrial production, increased surface area can be provided by microcarrier beads, but the associated increases incost and the resulting complexity of… more
Abstract:DESCRIPTION (provided by applicant): The use of research animals in research has been essential to development of vaccines and study of most human diseases. Modern rodent research is increasingly powerful with the ability to manipulate the genomes of miceand rats such that they closely mimic complex… more
Abstract:ABSTRACT: PSI will apply a novel form of unsupervised learning to the problem of detecting and identifying coordinated threats. Particular emphasis is placed on detecting motion based leading indicators of impending"swarming"attacks of small, low cost adversaries. The developed system… more
Abstract:The development of full motion video sensors on board unmanned platforms is quickly enabling persistent surveillance of areas of military interest in dense urban environments. Although the high resolution and update rate of persistent sensors facilitates tracking ground targets, serious tracking… more
Abstract:Recently, there have been significant theoretical advances in the fields of geo-statistics and spatio-temporal statistics. Unfortunately, the rapidly evolving technology has not yet resulted in off-the-shelf commercial toolkits, so the vast majority of the tools exist only as standalone, file based… more
Abstract:DESCRIPTION (provided by applicant): Cystic fibrosis (CF) is an autosomal lethal disease characterized that affects ~30,000 individuals in the US. CF lung disease, the major cause of mortality in CF, is caused by dehydration of airway secretions that leads to mucous adhesion, infection and airways… more
Abstract:DESCRIPTION (provided by applicant): Dry eye is one of the most frequently diagnosed ocular diseases affecting more than 5 million people in the United States alone. Dry eye is s a multi-factorial disease, resulting from a common etiology of insufficient tear film causing ocular surface damage and… more
Abstract:There is much interest within the accelerator physics community and DOEs Division of High Energy Physics for the development of a Muon Collider machine. A key challenge to realizing a Muon Collider is producing intense muon beams with small transverse emittances. For this project, we propose to… more
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