Abstract:Inovio Pharmaceuticals current minimally invasive dermal electroporation prototype device, which uses low voltage parameters to achieve both high and consistent levels of immunogenicity, offers an attractive option as an efficient and tolerable method for delivering DNA vaccinations in a clinical… more
Abstract:A new algorithm is proposed to identify hazards based on high-fidelity correlation between gene expressions and pathway signals. A software implementation based on'energy score'method has been developed to detect multiple gene interactions in the pursuit of specific signal pathways within… more
Abstract:We propose development of a feature discovery algorithm for identification of multivariate (or composition) biomarker signatures from high-dimensional omics data. The proposed algorithm operates on sets of heterogeneous features and returns a selected subset of significant features and a continuous… more
Abstract:Thermal Storage Systems proposes a lightweight mobile solar-powered hot-water ("SHW") system that meets or exceeds the requirements of the solicitation. We have placed particular emphasis on ruggedness, operational flexibility, 24-hour availability and ease of deployment. The proposed… more
Abstract:Commercially available solar water heating systems use mature renewable energy technologies which have been accepted for many years. However, they are often heavy (steel or aluminum frames, glass and steel pipe receivers encapsulated with glass insulating layers), are primarily designed for… more
Abstract:Armored vehicle crewmen, particularly drivers, have always been challenged by limited visibility. Vision blocks provide narrow and restricted views of the outside world and can severely impair driver performance, especially when operating at higher speeds and in complex urban environments. Drivers… more
Abstract:The objective of this research is to design, produce and manufacture an ultra lightweight runflat technology for Army vehicles, based upon the MKP patent-pending Negative Poisson Ratio (NPR) material system. Using MKPs award-winning virtual prototyping and design modeling and simulation (M & S)… more
Abstract:A powerful team of researchers from Northwestern University and MKS Technology has been assembled to develop a portable ultratrace level sensitive sensor for chemical warfare agents. The SERS technology will be developed and evaluated at Northwestern University while the materials and portable… more
Abstract:The objective of this proposal is to demonstrate the feasibility of using ultrasound induced neuromodulation to manage pain. SynSonix, LLC has been developing ultrasound neuromodulation (UNMOD) to noninvasively stimulate neural circuitry. Many studies have established the beneficial effects of… more
Abstract:Since the anthrax attacks of September-October 2001, the United States has developed and deployed several biothreat detection systems (most notably at various postal service locations). The most accurate systems utilize PCR technology and are therefore bulky, cannot be easily miniaturized, and… more
Abstract:The proposed project will develop a direct ethanol fuel cell (DEFC) system based on our recent research breakthroughs in non-platinum catalysts, alkaline ionomers, and anion-exchange-membranes. The AEM-DEFC system will have several advantages, including (1) non-Pt catalysts with ethanol tolerance… more
Abstract:IvySys proposes novel asynchronous signal sensing and automatic modulation classification (AMC) approaches that leverage a centralized network of low-cost asynchronous sensors to enable weak signal detection and classification. These innovative approaches will provide detection performance within 3… more
Abstract:The purpose of this program is to develop a clip-on thermal imager device that covers the full 40 degree field of view of the host night vision goggle. MTEQ"s approach utilizes a novel optical coupling technique coupled with the latest high resolution infrared focal plane arrays to provide up… more
Abstract:Protocol Technologies Group proposes to transform OPLANS and OPORDS from"dumb"text messages into"Smart Documents"(but distributed across the same messaging networks) capable of carrying information with them (e.g., maps, imagery), interacting with their surroundings (users and… more
Abstract:Today"s field-programmable gate array (FPGA) devices are expensive in size, power, performance, scalability and flexibility. The fundamental problem in these devices is the use of 2D-mesh interconnect architecture: it occupies large area, has long latency, consumes lots of power, and is not… more
Abstract:The need to develop an alternative technology to those that dominate the snack food industry has become apparent over the last decade. Quality, nutrition, functionality, health considerations articulated by the consumers coupled to efficiency, low energy requirements, low asset base, small process… more
Abstract:This project will design a mid-sized unmanned ground vehicle (UGV) system to support soldiers to effectively perform improvised explosive device defeat (IEDD) tasks remotely. IEDD task areas include navigation, hazard sensing, and neutralization. The control system willenable simple and safe UGV… more
Abstract:MACH-T3 will generate three concepts as described below in sufficient detail for a trade study to be performed. All concepts will meet the mandatory requirement of identical form and fit to the current BFV interface. Gear trains are the most efficient means for power transfer. As such, MACH-T3… more
Abstract:Creative Engineering Solutions, in collaboration with QinetiQ North America and its LAST armor solution, proposes to develop a switchable magnetic core element (SMCE) attachment system that breaks the traditional tradeoff of detachment time, isolation, pull strength, and weight which has been the… more
Abstract:The optical see-through Head Mounted Display (OST-HMD) is one of the enabling technologies for merging virtual views with a physical scene and provides a direct view of the real world through an optical combiner. It is highly preferred in demanding applications where a users awareness to the live… more
Abstract:Resource optimization strategies for engaging multi-stage, long-range missiles carrying multiple warheads during the ascent phase is an area of interest to MDA and the larger DoD community. The ability to rapidly predict the outcomes of extremely large numbers of decision permutations is crucial in… more
Abstract:This SBIR Phase II proposal to the Department of Defense, Army, requests funding for Innova Dynamics to optimize and scale up the Innlay-based IonArmour Next Generation technology for deployment, providing the highest levels of safe, cost-effective, continuous antimicrobial protection for military… more
Abstract:The proposed Phase II effort involves development and demonstration of an all-carbon fiber/epoxy aft shell body and integrated aft pusher assembly for gun launched hypervelocity applications. The all-carbon fiber technology is the selected approach for this effort, owing to the cost effectiveness,… more
Abstract:The use of materials other than steel in bearing liners lead to many problems associated with variations in thermal expansion coefficients. The use of an aluminum matrix composite minimized this problem because adding ceramic reinforcements to the aluminum matrix reduces the expansion coefficient to… more
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