Abstract:Positron Emission Tomography (PET) offers high sensitivity to a range of biological processes through the use of targeted radiolabeled probes. PET imaging can provide diagnosis for symptoms of diseases such as Alzheimers disease, head trauma, cancer, and stroke. In recent years, there has been… more
Abstract:Synchrotron radiation is a powerful tool for measuring structural properties of materials. Important applications of higher energy synchrotron X-rays include measurement of strain and material evolution during processing, studies of composite materials and studies of layered systems. Detector… more
Abstract:OBJECTIVE: To provide innovative technologies and system components which increase the lifetime and utility of various systems within DTRA"s Tag, Track, and Locate (TTL) portfolio to combat weapons of mass destruction (WMD). The specific innovations sought under this topic are improved… more
Abstract:ABSTRACT: Modern space electronics used for military space communications are susceptible to highly energized charged particles such as electrons and protons originating from coronal mass ejections that create geomagnetic storms. There is a need for advanced protection measures that can help… more
Abstract:Eddy current testing (ECT) is a widely practiced and critically important nondestructive evaluation (NDE) method used in aerospace, yet it relies on decades-old, wire-coil sensors. Flexible sensors are needed to inspect curved surfaces near the edges of components including wheel bead seats on… more
Abstract:The goal of the proposed Phase I is to demonstrate the feasibility of fabricating cost-competitive intermediate band light-harvesting solar cells with high conversion efficiency, through a combination of intermediate band physics and the unique structure of our proposed material. The most efficient… more
Abstract:Free space optical communication (FSOC) systems offer rapid data transfer rates, allowing practical wireless relay of complex data sets. To further promote the use of this technology for medium-range optical communication links operating with eye-safe ultra-violet (UV) sources, compact and robust… more
Abstract:Advanced CMC composites are currently being developed for various components in the propulsion system along the hot gas path, where pressures up to 3000 psi and flame temperatures from 4000 degrees F to 5000 degrees F are encountered. In order to achieve the lightest possible and optimal… more
Abstract:High capacity Thermal Management System (TMS) systems that can rapidly absorb peak waste heat using phase change, liquid to vapor, dissipating it gradually during normal operation, are the most ideal and most compact TMS possible for advanced weapon systems. These systems e.g. high power ADT/RF, are… more
Abstract:DESCRIPTION (provided by applicant): The objective of this proposal is to develop ultra-sensitive ELISA (Enzyme-Linked ImmunoSorbent Assay) methods for quantification of HIV p24 antigen. At present, the p24 antigen test is relatively insensitive, being able to detect only 5- 10 pg/ml. This quantity… more
Abstract:DESCRIPTION (provided by applicant): With over 8.5% of the U.S. population and 75 million people worldwide meeting the diagnostic criteria for alcohol use disorders (AUDs), alcohol abuse is among the top three preventable public health problems in the U.S.and the world. AUDs, commonly referred to as… more
Abstract:DESCRIPTION (provided by applicant): The objective of this work is to complete development of a novel antibacterial, acute hemodialysis catheter and conduct the preclinical testing required for FDA approval. This product will address 3 major unmet needs for intravenous catheters by: (1) providing… more
Abstract:ABSTRACT: Recent developments of advanced hybrid metallic structural concepts have been promising for enhancing durability and damage tolerance (D & DT) of unitized aircraft structures. The Alpha STAR team, comprised of Alcoa, Northrop Grumman (NGC), and Southwest Research Institute, proposes… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project has the goal of creating a signal amplification system that, while being inexpensive and simple to use, can be combined with antibodies or other probe molecules, and can increase detection limits of conventional ELISAs by 100- to… more
Abstract:In this SBIR project, AlphaSense, Inc. and the Carnegie Mellon University propose to develop a RF receiver front end based on CMOS-MEMS components for miniaturized digital EVA radio applications. In Phase I, we have proven the feasibility of implementing a compact, low power and high performance S… more
Abstract:In this proposal, AlphaSense, Inc. and the University of Washington detail the development of a novel, high performance Ka band power amplifier for EVA radio applications. Key innovations of our approach include: a) The application of a class-E power amplifier to ensure high power efficiency, b)… more
Abstract:In this proposal, AlphaSense, Inc. (AI) and the University of Michigan (UM) detail the development of a novel automated and controlled dual laser ablation system for selective chrome removal. The key innovations of this proposal include the following: a) The combination of ns- and fs- laser ablation… more
Abstract:In this proposal, AlphaSense, Inc. details the development of a novel sensor for pitting corrosion monitoring and load distribution measurements. The key innovations of this proposal include the following: a) corrosion and load distribution measurements based on the electrical impedance measurements… more
Abstract:In the current SBIR program, AlphaSense aimed at developing a novel, handheld, non-destructive sensor to evaluate the integrity of Naval Advanced Amorphous Coatings (NAAC) in real time. In phase I, we have proven the feasibility of using the cavity perturbation technique to detect different types of… more
Abstract:DESCRIPTION (provided by applicant): Organ transplantation is one of the great success stories of modern medicine. However, the supply of suitable organs lags far behind the need and many patients die while waitlisted for organs. While there have been manyrecent strides in organ procurement,… more
Abstract:Infrastructure compatible biofuels, produced by conventional processes and using non-food biomass, are currently too expensive. The proposed innovative lignocellulosic biomass to biofuels system uses a robust noncatalytic front end to create optimal hydrocarbon intermediates that are then cleaned at… more
Abstract:Active Denial Technology (ADT) and RF Vehicle Stopper devices need compact, light weight and low cost thermal management systems to meet mission goals. Heat exchangers strongly contribute to system volume, weight and cost. Innovative heat exchanger concepts have been identified that can reduce… more
Abstract:Heat recovered from Navy ship gas turbine engine exhausts could significantly reduce shipboard fuel use by providing heating, cooling or additional power output at no increase in fuel use. However, current heat recovery heat exchangers have durability problems, are too large for packaging in current… more
Abstract:To support tactical fuel requirements at forward bases, biomass wastes from operations, and those locally available, need to be converted into viable military fuels. Conventional approaches cannot produce military type fuels using compact and mobile reactors. Under a Phase I effort, Altex and… more
Abstract:Airborne high energy laser systems need lightweight and compact thermal management systems. Innovative heat exchanger concepts have been identified, which can help reduce thermal management system weight and volume to below 100 lbs and 8 cubic feet, respectively, while also reducing cost. Phase I… more
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