Abstract:Based on Cascade Designs expertise at developing individual water purification systems for the military and outdoor markets, we are proposing a novel in-line filter design that is based on incorporating multiple water purification technologies contained in a MOLLE compatible filter housing. Our… more
Abstract:At present, the predictive capability of simulation codes and models used in the conceptual planning and design of high-speed propulsion systems is limited by the ability to describe the complex flow fields inside the combustor, mixing models, detailed chemistry and turbulence-chemistry interactions… more
Abstract:ABSTRACT: Predicting the wall heat loading experienced by hypersonic vehicles during the transition from laminar to turbulent boundary layer flow is the grand-challenge tackled by the present proposal. Previous studies have not focused completely on this phenomenon. In this work we adopt… more
Abstract:LES will be used to calculate flow and noise issuing from realistic engine configurations such as realistic engine nozzle throats, serrated nozzles, straight ramp diffusers, and over/under expanded operation. Nozzle geometry and operating conditions can be specified by the government with the… more
Abstract:The overall objective of this proposal is to develop a physics based methodology that is capable of simulating two-way coupled, non-linear interaction of ship-airwake and helicopter rotor-wake in flow-through in a real-time fashion, and to demonstrate the prototype method in the Manned Flight… more
Abstract:The work proposed for this project arises from the need for modeling a realistic fuel atomization process in a complex combustor/augmentor fuel injector. In a real gas turbine combustor or augmentor, the injected liquid fuel undergo atomization for fast evaporation, mixing and combustion.… more
Abstract:Based on the successful separation of 20 compounds using a 1 m coated microcolumn in Phase I, we propose to design a new micro-gas chromatograph (microGC) system to separate and detect of all contaminants listed in NASAs "Spacecraft Maximum Allowable Concentrations for Airborne Contaminants… more
Abstract:Background: Surgical error reduction requires addressing rapid adoption of new surgical technology. We propose development of a networked surgical assessment platform able to collect performance and outcomes data from multiple surgical platforms and sites for dynamic metrics analysis. Goal:… more
Abstract:The ongoing military conflicts demonstrate the need to deploy skilled personnel equipped with advanced technology to provide medical and surgical attention as close as possible to the point of injury. A major problem is the occasional mismatch between the type of injury and the type of surgeon… more
Abstract:Our goal is to design and build a lightweight, wide area passive standoff imaging detection system capable of rapidly detecting liquids on surfaces for the purpose of contamination avoidance and reconnaissance. The envisioned technology extends the advantages of wide area passive infrared sensing… more
Abstract:Project goal is to develop and demonstrate a chemical/explosive sensor system to provide enhanced detection and classification in missions for which acoustic or optical imaging alone are not effective. The chemical sensor package developed and delivered during this SBIR effort will be lightweight,… more
Abstract:Ceebus Technologies is proposing a development plan to monitor diver vital biometric data and collect SCUBA status data, store the data, analyze and compare the data to normal, generate alerts or alarms if necessary, send the data to other underwater diver teammates and to a surface vessel. Sensors… more
Abstract:A continuing and growing threat to U.S. military personnel and civilians is exposure to toxic chemicals and pathogens. Useful detection systems exist, but it remains imperative to investigate next-generation technologies that have the potential to improve by an order of magnitude the cost,… more
Abstract:A continuing and growing threat to U.S. military personnel and civilians is exposure to toxic chemicals and pathogens. Because of this, detection of exposure to chemical and biological agents is a priority for biodefense, combat readiness, and public health. One promising approach is to measure… more
Abstract:DESCRIPTION (provided by applicant): More than 43,000 Americans die each year from liver disease, making it the 10th leading disease- related cause of death in the US. Cirrhosis with irreversible injury and scarring of the liver is the most prevalent causeof liver failure and is attributable to… more
Abstract:DESCRIPTION (provided by applicant): There is a worldwide consensus that islet transplantation may be considered a viable option for the treatment of insulin-dependent diabetes mellitus, and clinical trials are underway at many centers around the world. Asthis approach for curing diabetes… more
Abstract:DESCRIPTION (provided by applicant): Twenty four million Americans are affected with end-stage lung disease which is the 4th leading cause of death in the US, and there are currently 2,122 candidates on the lung transplant waiting list. Emphysema and chronic obstructive pulmonary disease are the… more
Abstract:DESCRIPTION (provided by applicant): Vascular grafting is performed clinically to repair or replace diseased coronary artery and peripheral vessels to restore normal blood flow patterns. Synthetic grafts composed of polymers such as Dacron and expanded polytetrafluoroethylene do not work well in… more
Abstract:DESCRIPTION (provided by applicant): Tissue digestion and cell extraction is a core element of a variety of bioprocessing methods ranging from isolation of the rare cancer stem cell for basic research to the purification of human islets or adipose-derivedmesenchymal stem cells for transplant. While… more
Abstract:DESCRIPTION (provided by applicant): The cultured cell has emerged as a critical link in the translation of research in the various fields of biotechnology and biomedicine. An unprecedented increase in the demand for cultured cell products is now drivenby the growth in biopharmaceuticals, cancer… more
Abstract:DESCRIPTION (provided by applicant): The results of early clinical trials using stem cells clearly offer the promise of a new path to addressing a variety of medical problems that range from creating engineered tissues for autologous grafts to repairing a variety of organs. Mesenchymal stem… more
Abstract:DESCRIPTION (provided by applicant): The goal of this proposal is to complete development of a Microfluidic Liver Array (MLA) platform for improved and lower cost in vitro toxicity screening targeting the human liver. This funding will directly lead tothe commercialization of a product with … more
Abstract:DESCRIPTION (provided by applicant): Targeted therapies have the ability to specifically interact with and block proliferation of cancer cells by interfering with targeted gene products required for the malignant phenotype. Unlike conventional cancer chemotherapies, targeted therapies do not harm… more
Abstract:With the rapid strides in various avionics-related technologies, the need for advanced simulators will increase. Anti-jam receiver development and future improvements in PNT are critically dependent on the availability of advanced simulators. The needs include: flexible, accurate, adaptable,… more
Abstract:TRS Technologies proposes to develop a very wideband ultrasound diagnostic tool for quantification of trabecular bone properties for astronauts in long term space missions. Loss of calcification in bones and general loss of strength must be monitored in missions to insure personnel health, however,… more
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