Abstract:DESCRIPTION (provided by applicant): Portable Lab-on-a-chip Flow Cytometer: Prototype and Application Development NanoSort RESEARCH and RELATED Other Project Information 7. PROJECT SUMMARY The lab-on-a-chip NanoSort device proposed here advances the achievements of the Phase I Beta Prototype project… more
Abstract:Cancer is a complex and diverse disease whose treatment can be improved by more sophisticated early detection and monitoring. NanoSort, Inc. proposes to build a lab-on-a-chip microfluidic device platform that can detect and quantify up to 32 multiplexed analytes for the detection and monitoring of… more
Abstract:DESCRIPTION (provided by applicant): Ion channels are membrane proteins that allow the selective movement of charged molecules through cellular membranes. Many disease states, such as cystic fibrosis, muscular dystrophies, hypertension, and cardiac arrhythmias are caused by ion channel pathologies.… more
Abstract:DESCRIPTION (provided by applicant): (Phase-2, Renewal) The SACC-Substance Addiction Collaboration Channel(R) platform is a new Collaboration, WEB-2.0 springboard specifically designed to structure and share information across the Behavioral/Mental Health Workforce community with the special… more
Abstract:Optical Engines has developed and demonstrated a high power pump combiner in the co-propagating direction with 94.5% pump efficiency and a 20dB PER with zero brightness drop. This combiner has been tested for extended periods (approx 1 Hr) with 1.5kW of pump power with no degradation. This was… more
Abstract:DESCRIPTION (provided by applicant): Aggregation in antibody therapeutics is a topic of increasing concern in the biopharmaceutical industry, as these aggregates are believed to play an undesirable role resulting in adverse health effects to patients by inducing immunogenicity, altering therapeutic… more
Abstract:DESCRIPTION (provided by applicant): Despite notable achievements over the past two decades, cancer remains a challenging 21st century epidemic demanding new, more effective drugs. Nitric oxide (NO) is well known to kill cancer cells without harming normal bone marrow cells, but until now has not… more
Abstract:DESCRIPTION (provided by applicant): The overall objective of this project is to productize and commercialize a markerless motion capture system for applications in biomechanical and clinical practice. The markerless system, as opposed to traditionally used marker based systems, would provide… more
Abstract:Microchannel Plate event multipliers capable of operation at cryogenic temperatures are currently not commercially available from any supplier. The proposed development of cryogenic-compatible MCPs will enable photon/electron/ion/alpha detection with high spatial resolution and sub-nanosecond event… more
Abstract:DESCRIPTION (provided by applicant): During the past decade, the discovery of kisspeptin peptides and their cognate receptor KISS1R (aka GPR54) has expanded our mechanistic understanding of the hypthothalamic-pituitary-gonadal (HPG) axis. The kisspeptin system has been shown to be an integrator of… more
Abstract:DESCRIPTION (provided by applicant): This Fast-Track SBIR proposal submitted by SoloHealth of Duluth, Georgia, requests grant funds to build and test a multifunction health-screening kiosk. Our current kiosk prototype, EyeSite, has demonstrated efficacy inreaching low income, high health disparity… more
Abstract:In order to counter emerging threats from the Middle East and Southeast Asia, the Ballistic Missile Defense System (BMDS) is acquiring new sensor (e.g. AN/TPY-2 and PTSS) and weapon technology (SM-3). As these new technologies becomes fielded, the BMDS's Command, Control Battle Management and… more
Abstract:One of the primary research objectives for multi-sensor data fusion within the Ballistic Missile Defense System (BMDS) is the development of novel techniques to enable robust target discrimination. While great strides have been made in recent years to advance capabilities through the use of… more
Abstract:Missile Defense Agency (MDA) recently adopted the Phased Adaptive Approach (PAA) to enhance the Ballistic Missile Defense System"s (BMDS) ability to counter emerging threats in the Middle East and Southeast Asia. PAA primarily focuses on fielding new sensor technology (e.g. AN/TPY-2, ABIR, and… more
Abstract:ExoAnalytic Solutions proposes to develop a star catalog and in-band irradiance simulation by leveraging our in house star background model called STARS (Stellar Track And Radiance Simulation) v1.0 and the Exo6Sim optical focal plane scene generation simulation. STARS v1.0 uses a stellar spectrum… more
Abstract:ABSTRACT: Over the past twenty years, the United States and other nations around the world have become dependent on space technology for communications, precision tracking and many other applications, causing the space domain to become both contested and congested. To maintain Unites States space… more
Abstract:Democracy relies on informed and active participation of citizens. This project team is developing a prototype of a formative assessment component to be added to the GoCivics games, a tablet-based intervention through which middle school students engage in compelling learning activities and… more
Abstract:Studies show that many American students do not possess basic knowledge of the America judicial branch of government, one of three pillars upon which democracy rests. This project team is developing a prototype of the GoCivics Mock Trial, a multiplayer, augmented reality, role-playing game for use… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will produce a set of engaging educational video games and associated teaching compendiums for middle school physical science classrooms that are optimized for students with diverse sets of learning needs, including those with learning… more
Abstract:Goals of 80% clean energy production for the United States by 2035 and 20% of the countrys power being supplied by wind energy by 2030 imply nearly a tenfold increase in wind power production. This means that the need for forecast information will extend to longer projection windows with increasing… more
Abstract:ABSTRACT: Future Operationally Responsive Space (ORS) missions will require significant capabilities in onboard and ground-based automation and autonomy, including event detection, planning and scheduling (P & S), and task execution. Onboard P & S is particularly challenging, because of… more
Abstract:Increased use of hydrogen as a fuel can provide benefits to our nations energy security, the environment and economic growth. Toward hydrogen economy, an innovation in hydrogen separation technology is needed in the production of hydrogen. Current separation technologies for industrial hydrogen… more
Abstract:This Small Business Innovation Research Phase I project will develop a novel ion gate membrane with controlled pore size for redox flow battery. Redox flow battery is one of the most promising electric energy storage (EES) technologies. However, the cost of the state-of-the-art (SOA) membrane used… more
Abstract:Increasingly strict environmental regulations, surging energy demand and oil prices, the proliferation of the internet and (hybrid) electric vehicles have given rise to new growing market demand for efficient, clean and renewable energy sources. It is projected that world energy consumption will… more
Abstract:The U.S. Military has a strong need for very high-energy density (>1000 WH/kg), light weight power sources for communications and other advanced electronic devices The possible solution is replacing the battery with proton exchange membrane (PEM) based hydrogen fuel cell. However, hydrogen… more
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