Abstract:The dramatic increase in development and usage of nanostructured materials has left a critical characterization gap in the ability to chemically identify and map materials with nanoscale spatial resolution. Anasys Instruments proposes to develop a high speed Wideband Infrared NanoSpectroscopy (WINS)… more
Abstract:DESCRIPTION (provided by applicant): Currently, about 20 million Americans have some form of thyroid disease. Thyroid disease occurs when the thyroid gland does not supply the appropriate amount of thyroid hormone needed. Thyroid and parathyroid diseases combine the fields of endocrinology and… more
Abstract:DESCRIPTION (provided by applicant): In this project, the breakthrough new technique of nanoscale infrared (IR) spectroscopy, pioneered by Anasys Instruments, will be adapted and refined for Pharmaceutical and biological systems. The technique has numerousapplications such as Polymorph screening;… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will develop technologies to enable commercialization of nanoscale Dynamic Mechanical Analysis (DMA). Conventional DMA works by applying an oscillating stress to a sample and measuring the time-dependent strain. Analysis of DMA data… more
Abstract:Infrared spectroscopy is the most widely used technique for chemical characterization with a worldwide market of over $1B annually. Conventional IR spectroscopy suffers, however, from fundamental spatial resolution limits at the scale of many microns to many tens of microns. This has prevented… more
Abstract:ABSTRACT: The engineer will be guided through the creation of criteria, alternatives and evaluation techniques in order to make a better decision. BENEFIT: The engineer will be guided through the creation of criteria, alternatives and evaluation techniques in order to make a better decision.
Abstract:ABSTRACT: As we move from a paper-based world into a digital environment, the internet will soon evolve from a virtual documentation system into a vibrant ecosystem of data where documents and human actors play an even smaller role. We are currently reaching a tipping point in history concerning… more
Abstract:ABSTRACT: Within the last decade, game theoretic approaches have emerged as viable tools to analyze distributed wireless resource allocation problems and design distributed transmission strategies. Conventional game theoretic designs for wireless resource allocation problems do not consider jamming… more
Abstract:ABSTRACT: The ultimate objective of the joint effort is to develop technology that will enable next-generation cognitive wireless networking between USAF space, air, and ground assets and achieve significant improvement in network throughput, delay, and reliability. Current practices that evolve… more
Abstract:The focus of this research will be on developing a tool to model the electromagnetic vulnerability and susceptibility of electronic systems, subsystems, and components to directed-energy HPM weapons. In particular, we propose to develop a conceptual framework consisting of an analytical approach and… more
Abstract:The focus of this research will be on developing an automated simulation tool called E3Expert-Plus that will predict and mitigate intrasystem (cosite) interference while integrating with existing databases of radio frequency (RF) component and equipment characteristics. As part of this effort we… more
Abstract:This effort considers the problem of Automatic Modulation Classification (AMC) using multiple asynchronous sensors in non-cooperative environments under low signal-to-noise ratio (SNR) regimes. The goal is to improve and demonstrate the performance of AMC systems on various weak signal scenarios in… more
Abstract:This Small Business Innovation Research Phase I project aims to undertake a feasibility study of printing ultra-pure semiconducting and metallic single-walled carbon nanotube (SWCNT) inks as channel materials and electrodes of thin-film-transistors, and to fabricate all-SWCNT circuits such as… more
Abstract:ABSTRACT: We aim to undertake a Phase I study on radiation hardened graphene memory devices for military and space applications. This project will focus on developing a nonvolatile single-layer graphene ferroelectric field-effect transistor (FET) memory device. This device incorporates… more
Abstract:ABSTRACT: Our Phase II project on"Carbon Nanotube (CNT) Based Electronic Components for Unmanned Aircraft Systems (UAS)"will aim to model, design, fabricate, optimize and characterize RF CNT devices and circuits that are critical for RF transceiver applications in radar, communications… more
Abstract:DESCRIPTION (provided by applicant): Alcoholic and non-alcoholic liver fibrosis remains an unsolved challenge for the hepatologist as it can lead to cirrhosis and end-stage liver disease, a life-threatening condition that necessitates liver transplantation. Current therapeutic strategies for the… more
Abstract:DESCRIPTION (provided by applicant): Scleroderma (also known as systemic sclerosis-SSc) is characterized primarily by progressive dermal and vascular fibrosis. Other organs are affected too, including lung, heart, blood vessels, GI and kidney. Many patients who suffer from scleroderma/SSc also have… more
Abstract:DESCRIPTION (provided by applicant): Chronic kidney disease (CKD) remains an unsolved challenge for the nephrologist, as it almost inevitably leads to end-stage renal failure, a life-threatening condition that necessitates renal replacement therapy. Few, if any, of the currently practiced… more
Abstract:DESCRIPTION (provided by applicant): Ischemic Stroke continues to be a major cause of morbidity and mortality in the United States. Currently approved thrombolytic therapy suffers for a narrow therapeutic window and clearly other therapeutic strategies areneeded, such as neuroprotective or… more
Abstract:DESCRIPTION (provided by applicant): Systemic sclerosis (SSc) or diffuse scleroderma is a complex, chronic, autoimmune, connective tissue disease which primarily causes skin thickening and hardening in addition to interstitial fibrosis of lungs, gastrointestinal tract and arteries. Estimates of the… more
Abstract:DESCRIPTION (provided by applicant): Idiopathic pulmonary fibrosis (IPF) is a progressive, agonizing, debilitating and routinely fatal disease that afflicts 200,000 individuals in the United States and five million patients worldwide. There are currentlyno effective treatments available for this… more
Abstract:DESCRIPTION (provided by applicant): Myocardial infarction (MI) is a significant cause of morbidity and mortality in the U.S. H2 Relaxin (H2R) is a Phase III clinical trial-stage peptide that exhibits both anti-inflammatory and cytoprotective activities which can potentially be harnessed for the… more
Abstract:The objective of this project is to develop a portable, passive system for rapid and efficient blood component separation. While a number of macroscale devices (based on centrifugation) are routinely employed in laboratory settings to separate red blood cells (RBCs) and platelets from plasma, they… more
Abstract:ANTEOS, Inc. proposes to develop new generation of photonic crystal laser diodes with narrowed emission spectrum, improved thermal stability and overall performance for application in diode-pumped alkali vapor lasers (DPAL) systems. Already demonstrated proprietary process will be employed for… more
Abstract:For humans and robots to effectively work together, they must share a common understanding of concepts defining the environment and the relationship of those concepts. In this proposal, we present an approach for dynamic interface creation which takes advantage of a robot-centric ontology. We first… more
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