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Year:2012
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Displaying 5501 – 5525 of 5641 Awards
Company: ASTRAEA THERAPEUTICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Sickle cell disease (SCD) is associated with severe pain, which remains a major challenge to treat. Opioids are the current standard of care, but due to side effects and development of tolerance and dependence, remain asub-optimal approach to treat SCD pain,… more
Company: SHEIDOW CONSULTING, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Drug abusing and dependent youth represent a greatly under-served population at high risk of presenting significant deleterious long-term outcomes for themselves, their families, communities and society at extraordinary long-term costs. Adolescent substance use… more
Company: RMC RESEARCH CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The past decade has seen growing concern over the nonmedical use of prescription opioids and over substantial increases in public health consequences of prescription opioid misuse. Increased rates of neonatal abstinencesyndrome, a constellation of symptoms… more
Company: MIND SET TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Tinnitus affects 12 - 17% of the population or 36-50 million Americans according to the American Tinnitus Association. The constant sensation of ringing in the ears is a debilitating condition and 2 to 3 million Americans are disabled by it. Th approximate loss… more
Company: PASSY-MUIR, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Over 50% of patients post stroke have swallowing disorders (dysphagia) placing them at risk for aspiration of medications, food and liquids into their airway. Continued aspiration is life threatening as it can frequently lead to pneumonia requiring hospital… more
Company: THEO CHOCOLATE, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this Phase 1 SBIR application is to identify and structurally characterize compounds in chocolate that could be used to treat tissue inflammation associated with gingivitis and periodontitis. Previous studies have demonstrated that water soluble… more
Company: KOAG MEDICAL, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): There is need for an improved, hemostatic dressing to control renal hemorrhage associated with new nephron-sparing endourologic procedures such as laparoscopic partial nephrectomy (LPN). Our surgical laboratory and small business (KOAG) has developed a… more
Company: INNOVATIVE RESEARCH SOLUTIONS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): We are developing a novel two-part cold high-level disinfecting (HLD)/sterilization technology that will be ready to work by mixing in water, just minutes before use. Both components separately are relatively inactive,non-toxic and stable chemicals that have good… more
Company: MEDIKINE, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Medikine will use SBIR funding to develop a novel therapeutic approach for treating diabetic nephropathy (DN) - a major life-threatening complication of diabetes, and the leading cause of chronic kidney disease and kidney failure in the United States. In 2008 DN… more
Company: BIODEL, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): A device system which automatically maintain blood glucose concentrations in the normal range by dosing insulin in response to continuously sensed glucose concentration data represents a modern attempt to mechanically simulate normal beta cell physiology and… more
Company: BIODEL, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Extreme insulin resistance in patients with diabetes is defined as insulin dose requirement of greater than 200 units daily. Currently, U-500 regular insulin is frequently used to treat these patients, however, the slowabsorption and prolonged duration of action… more
Company: DUOPHOS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): With 500,000 Americans in the final stage of chronic kidney disease (CKD) and another 40 million at risk for developing CKD due to obesity, diabetes and hypertension renal disease is a modem epidemic. Serum phosphorus (Pi) levels are thought to be the crux of the… more
Company: ANATOMYWORKS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The overall goal of this application is to develop electronic mouse atlases for image-guided stereotaxic operations. In mouse-based neuroscience studies, stereotaxic operations are an essential technology, in which chemicals, vectors, cells, or electrodes are… more
Company: ANATOMYWORKS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The overall goal of this application is to develop an automated and quantitative analysis tool for brain MR images. The technology is based on the MriStudio program developed by Drs. Mori and Miller, which is characterized by accurate multi-modal diffeomorphic… more
Company: PRECIBIO MEDICAL DEVICES, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): In the project, We propose to develop compliant restraining devices for mice during imaging applications. Mice are used in biomedical research in order to understand the human body, determine the effects of diseases, and develop treatments for diseases in humans.… more
Company: DEEPSEMAPHORE, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Project summary: The project summary with the exception of the first five lines contains proprietary/privileged information that Dr. Ramloll requests not be released to persons outside the Government, unless for purposes of review and evaluation. (Number of… more
Company: XEN BIOFLUIDX, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Autism spectrum disorders (ASD) currently affect about 1 in 110 children in the US, and are associated with a high economic cost to both families and society. There are currently no consistent biological markers for Autism, and diagnosis is currently based upon… more
Company: BIOPICO Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Multiplexed Onchip Nanomagnetic Immunoassay for Toxin Reporting (MONITOR) Micro/Nano engineering techniques such as lab-on-a-chip technologies and nanoparticulates sensors are emerging as the next revolution tools for integrated high sensitive high throughput… more
Company: NEWOMICS, INC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): One of the most exciting developments in environmental science and technology is the emerging field of exposomics , i.e., rapid and sensitive detection of large sets of analytes ( exposome ) reflecting the complexity of exposure in the personal environment… more
Company: BROCKMAN-HASTINGS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Brockman-Hastings LLC seeks to reduce vision loss for glaucoma sufferers by creating a simple, accurate, and clinically acceptable sensor for monitoring intraocular pressure (IOP). Trends indicate that by 2020, approximately 80 million people worldwide will… more
Company: MITOCHEM THERAPEUTICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Retinal degeneration can be triggered by environmental insults as well as genetic mutations. The role for most disease genes is unclear and pathological processes are influenced environment making it difficult to identify one central cause. Indeed, the… more
Company: ONL THERAPEUTICS, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Death of photoreceptor cells is a consequence of many acute as well as chronic retinal diseases which lead to severe vision loss in patients. If photoreceptors could be helped to survive the period of disease, the visual outcomes for patients would be… more
Company: ENCORE VISION, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Encore Vision has identified an innovative treatment for Presbyopia. The aim of the proposed phase I studies is to develop a topical ocular formulation of our co-drug to achieve therapeutic levels of active agent in therabbit aqueous humor without adversely… more
Company: INTEGRATED DYNAMIC ELECTRON SOLUTIONS Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Plans for the design, construction and demonstration of the world's first optically driven transmission electron microscope phase plate are described. This technology, known as a Ponderomotive Phase Plate, utilizes a focused laser to create a well defined… more
Company: GENETIVISION CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The ultimate goal of this proposal is to generate, maintain, and distribute a new collection of duplication stocks that covers the entire euchromatic autosomal portion of the Drosophila melanogaster genome. Since this collection will represent a powerful new set… more
Displaying 5501 – 5525 of 5641 Awards
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