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Year:2012
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Displaying 5551 – 5575 of 5642 Awards
Company: DOSECUE, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Our objective is to provide patients and physicians with an effective new tool to increase patient compliance (aka adherence) to prescription drug regimens. Poor patient compliance diminishes patients' health, increasespreventable morbidity, and results in… more
Company: MOSAIC LOFT Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Errors in the administration of medications to residents of long-term care facilities (LTCFs) threaten resident safety and add significant unnecessary costs to the healthcare system. Use of unit dose medications that require LTCF staff to manually sort and… more
Company: WINSTON PHARMACEUTICALS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The project is the initial proof of concept clinical study of Civamide Nasal Spray for the treatment of postherpetic neuralgia (PHN) of the trigeminal nerve [(TN), a severely disabling facial pain syndrome]. Civamide Nasal Spray as a treatment for PHN of the [TN]… more
Company: RENOVO NEURAL, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Multiple sclerosis (MS) is the most common inflammatory demyelinating disease of the central nervous system (CNS) and is the major cause of non-traumatic neurological disability in young adults in North America. Although the etiology of MS is not clear, its onset… more
Company: NEUROTARGETING SYSTEMS Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Our goal is to develop an efficient and inexpensive toolkit for ablating or reversibly inactivating specific cell types in the brain or other organs of mammals. We propose new techniques in which the genes for nitroreductase (NTR) or Drosophila allatostatin… more
Company: SENEB BIOSCIENCES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Huntington's disease (HD) is a neurodegenerative disorder characterized by chorea and progressive motor, psychiatric and cognitive decline. GM1 depletion is validated as a therapeutic target for Huntington's disease (HD) in preclinical studies in which… more
Company: COGNITION THERAPEUTICS, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Recent key scientific discoveries have identified oligomers of the protein Abeta 42 as the synaptotoxic culprits in the Alzheimer's disease process. With increasing age, decline in brain levels of Abeta binding and clearance proteins and elevations in enzyme… more
Company: GENESEARCH, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): This Project, the Dracula Pipette Project, is intended to improve on a device invented by the Project Director (Dr. Paul Taylor) and to find ways to manufacture the device for general use. The device is a co-axial microinjection tool in which the injection… more
Company: CELLTRONIX Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Cryopreservation of germplasm (GP) (sperm, oocytes, embryos, stem cells, ovarian tissues) is essential for preserving the genetic variety of model animals, reproductive health in humans, the animal breeding industry andwildlife conservation. Although many methods… more
Company: FACTOR BIOSCIENCE, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The annual cost of care for Alzheimer's disease (AD) in the US is currently estimated at 200 billion, and is expected to rise to 1.1 trillion by 2050. Despite these costs and the prevalence of the disease (1 in 8 older Americans has AD), the etiology of… more
Company: FACTOR BIOSCIENCE, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Methods for controlling cell-type by dedifferentiation, directed differentiation, and transdifferentiation or direct reprogramming have enabled the generation, in the laboratory, of tissue-specific, patient-specificcells from small, non-invasive skin samples.… more
Company: CYTOVERA, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): This project aims to develop a novel microfluidic device that preserves the maximal viability and potency of cord blood stem cells, in order to render cord blood transplantation effective for adult patients with leukemia, lymphoma, and other serious blood and… more
Company: DIASSESS Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION: Multiplexed point-of-care diagnostics for many synergistic diseases presents a fundamental challenge: a state-of-the-art diagnostic assay will require both protein and nucleic acid detection in a single platform. In addition to this requirement, it is critical that the diagnstic… more
Company: CORENGI, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Conducting and completing clinical trials relies on successful recruitment of enough patient volunteers, who are appropriate matches, for any given study. Corengi, Inc. has developed a technology platform that supportsa dedicated website with a matching engine… more
Company: OPUS KSD, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The goal of this project is to develop a multi-suture delivery device capable of inserting bioabsorbable fasteners, with improved cost/performance over all other skin closure methods, and demonstrate safety and efficacyin animal trials. Traditional stitches and… more
Company: Health Fidelity, Inc. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The adoption of electronic health record (EHR) systems is a national healthcare priority. However studies show massive physician productivity drop of up to 25-40% upon transition to EHR. The majority of workflow delay is based on the need to perform manual… more
Company: ACLARIS MEDICAL, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Post-traumatic stress disorder (PTSD) and its consequences place a large burden on the public and on the individuals who suffer from it, yet the clinical evaluation of PTSD is limited by its dependence on the subjectiveself-report of patients. Physiological… more
Company: QURVE LEARNING, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Mortality from colorectal cancer (CRC) can be reduced through screening programs. Regardless of the primary strategy (fecal occult blood testing, sigmoidoscopy, colonoscopy, fecal DNA, computed tomographic colonography[virtual colonoscopy]) colonoscopy is… more
Company: MARKETZERO, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Tobacco use is the leading cause of cancer death. While daily tobacco consumption in the United States has declined to 18.1%,1, 2 nondaily smoking (smoking on some days but not every day) is increasing,3 particularly among young adults.2 Yet, nondaily smokers are… more
Company: RINGFUL, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Adherence with prostate cancer screening (such as PSA tests, and physician follow-ups), is less than perfect. In large part, this is because members of at-risk populations need to keep track of which tests are requiredand at what time. As screening guidelines and… more
Company: KRIKORJAN, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Of the 24 million patients diagnosed with diabetes in the US, 6.5 million (27%) depend on a strict regime of insulin administration. Limited or unreliable patient reporting of critical diabetes care parameters (blood glucose measurements, carbohydrate intake, and… more
Company: NANOMEDIC, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Postmenopausal osteoporosis is a more dangerous disease than previously thought and is one of the most common diseases in older women. One in two women over age 50 will have an osteoporosis-related fracture during their lives, and fractures in postmenopausal… more
Company: SIMPLEC, LLC Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): This Fast-Track SBIR application submitted by SimpleC of Atlanta, Georgia, requests funds to test our current behavior management technology for persons with dementia (PWD), the SimpleC Companion, and to develop and test a new mobile tablet, the SimpleC Wellness… more
Company: ORASURE TECHNOLOGIES, INC. Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): The objective of this research application is the development of a simple, highly portable test system for rapid screening for human immunodeficiency virus (HIV) and hepatitis at the point of care (POC). This test system will be capable of identifying patients… more
Company: PRELUDE CORPORATION Agency/Program/Year/Phase: HHS / SBIR / 2012 / 1
Abstract: DESCRIPTION (provided by applicant): Ductal carcinoma in situ (DCIS) is a non-invasive form of breast cancer. The lesions are typically surgically removed. However, there is a risk of recurrence as another DCIS or as a more dangerous invasive cancer. If the DCIS is large, full mastectomy is used,… more
Displaying 5551 – 5575 of 5642 Awards
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