Abstract:DESCRIPTION: Post-translational modifications of proteins (PTMs) play a central role in diverse cellular processes including protein folding, targeting, signal transduction, immune response, adherence, motility and protein degradation. Over 300 differenttypes of PTMs are already known and are… more
Abstract:Significant progress has been made recently in developing multi-analyte prognostic cancer signatures based on gene expression profiling (GEP). However, current industry-standard RT-PCR platforms require substantial amounts of clinical samples, such as multiple FFPE tumor sections. These large sample… more
Abstract:For supporting NASA's Robotics, Tele-Robotics and Autonomous Systems Roadmap, we are proposing the "Evolutionary Autonomous Health Monitoring System" (EAHMS) for planetary exploration, which will provide an integral flexible diagnostics and prognostics framework by advanced and novel… more
Abstract:American GNC Corporation (AGNC) and Louisiana Tech University (LaTECH) are proposing a breakthrough technology consisting of an innovative system for facilitating the monitoring and management of NASA test facilities (such as rocket engine test stands) and widely distributed support systems (WDSS).… more
Abstract:The objective of this project is to demonstrate the feasibility of a Gyrocompassing Based Attitude and Azimuth Determination System Using MEMS Inertial Sensors. This attitude and azimuth determination system can be used in a handheld laser range finder for providing targeting capability for… more
Abstract:To support U.S. Navy mission readiness for carriage life monitoring and dynamic event tracking of external stores, AGNC is proposing an autonomous vibration-based system that performs event detection and identification (EDI). The AISTS builds on state-of-the-art spectrum data analysis, embedded low… more
Abstract:Aging and obsolescence issues have recently led to problems with the rod control systems of existing pressurized water reactors. These issues, along with plans for plant life extension, have prompted the industry to actively seek viable options to monitor the health of these systems in order to… more
Abstract:Current designs of Light Water Reactors (LWR) are equipped with control and shutdown rods that are inserted and withdrawn from the reactor core for reactivity control. In particular, the Control Element Drive Mechanism (CEDM) system is widely used for regulating plant power levels and core power… more
Abstract:Small modular reactors (SMRs) are at the forefront of the nuclear industrys options for deployment of new reactors to meet the growing electricity needs of the world. However, the designs of SMR plants are not yet far along enough to know the type and number of instruments that will be included in… more
Abstract:Our team proposes a unique expendable acoustic source comprised of flexural disc technology in a close packed arrangement that allows for a reduction in resonant frequency and an increase in useful bandwidth. This array will be designed to couple as much energy as possible into the bottom sediments,… more
Abstract:The proposed 45 nm radiation hardened platform based structured ASIC architecture offers the performance and density expected of a custom ASIC with the low manufacturing cost associated with a structured ASIC. The low cost, high performance customization of the structured ASIC portion of the chip is… more
Abstract:ABSTRACT: American Semiconductor will develop and demonstrate structural integration of a conformal load bearing antenna structure (CLAS). Future aircraft will incorporate distributed electronics, sensors, and flight control transducers directly into the composite airframe. For near-term Air… more
Abstract:Research on utilizing inexpensive and personal-level parallel computing architectures to speed up the implementation of the class of particle filters is proposed. This study will leverage NVIDIA Graphics Processing Units (GPUs) and multi-core CPUs that are quickly becoming commonly available for… more
Abstract:DESCRIPTION (provided by applicant): In the present STTR we propose to investigate two novel approaches in our exploration of the therapeutic and regenerative potential of cell-based medicine. Furthermore, we will utilize a preclinical animal model of compression syndrome (CS) that mimics the… more
Abstract:The long-term goal for this effort is to develop a low-cost, high-temperature thruster. Within the attitude control propulsion community, many efforts have focused on development of ultra-high temperature precious metal alloys and systems that give long life and good performance (e.g., Ir/Re). … more
Abstract:ABSTRACT: In the proposed effort, ASI will demonstrate the feasibility of a practical, proven method for significantly increasing the heat transfer coefficient inside regenerative cooling channels. The technique, used in the electronics industry for high heat flux removal applications, requires… more
Abstract:DESCRIPTION (provided by applicant): Volitional, coordinated movement depends on proprioception to the extent that a loss of proprioception can lead to a lifetime of dyscoordinated movement. Proprioception can be adversely affected by spinal cord injury(SCI), stroke, and traumatic brain injury… more
Abstract:ABSTRACT: Accurate, in-situ meteorological data are an essential part of any flight-test program or airborne weapon test. Present methods to gather such data are subject to drawbacks including spatial inaccuracy, asset availability, and simple inefficiency. An in-situ radiosonde system capable… more
Abstract:The dramatic increase in development and usage of nanostructured materials has left a critical characterization gap in the ability to chemically identify and map materials with nanoscale spatial resolution. Anasys Instruments proposes to develop a high speed Wideband Infrared NanoSpectroscopy (WINS)… more
Abstract:DESCRIPTION (provided by applicant): Currently, about 20 million Americans have some form of thyroid disease. Thyroid disease occurs when the thyroid gland does not supply the appropriate amount of thyroid hormone needed. Thyroid and parathyroid diseases combine the fields of endocrinology and… more
Abstract:DESCRIPTION (provided by applicant): In this project, the breakthrough new technique of nanoscale infrared (IR) spectroscopy, pioneered by Anasys Instruments, will be adapted and refined for Pharmaceutical and biological systems. The technique has numerousapplications such as Polymorph screening;… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will develop technologies to enable commercialization of nanoscale Dynamic Mechanical Analysis (DMA). Conventional DMA works by applying an oscillating stress to a sample and measuring the time-dependent strain. Analysis of DMA data… more
Abstract:Infrared spectroscopy is the most widely used technique for chemical characterization with a worldwide market of over $1B annually. Conventional IR spectroscopy suffers, however, from fundamental spatial resolution limits at the scale of many microns to many tens of microns. This has prevented… more
Abstract:ABSTRACT: The engineer will be guided through the creation of criteria, alternatives and evaluation techniques in order to make a better decision. BENEFIT: The engineer will be guided through the creation of criteria, alternatives and evaluation techniques in order to make a better decision.
Abstract:ABSTRACT: As we move from a paper-based world into a digital environment, the internet will soon evolve from a virtual documentation system into a vibrant ecosystem of data where documents and human actors play an even smaller role. We are currently reaching a tipping point in history concerning… more
There are several categories such as “By Agency”, “By Year”, “By State” etc.
Select a checkbox within a category to refine your search results.
Each of your selections is listed in the “Narrow Search Filters” bar. You can uncheck these selections to remove them.
Search for Either Criteria
When you select multiple values within a category, the results will include values that match either of the selections.
For example, selecting “2005” and “2007” in the “By Year” category will display results that include either 2005 OR 2007 in the results.
Narrowing the Search Results
You can refine your search results across categories. To narrow down your results, select multiple values across different categories. The results will only include values that match the selections across the categories.
For example, selecting “2005” in the “By Year” category and “NASA” in the “By Agency” category will only display the results that contain both “2005” AND “NASA” in the results.