Abstract:Human plasma offers the promise of a revolution in biomarker-based disease diagnosis and therapeutic monitoring. Absence of a trained phlebotomist in remote locations limits the diagnostic potential of the human proteome, as current self-administered point-of-care extraction volumes are insufficient… more
Abstract:To address the Office of the Secretary of Defense, Defense Health Program"s (OSD/DHP) need for an innovative concept for effective, objective diagnosis of subjective tinnitus in military personnel, ChromoLogic (CL) proposes to develop the OPical TINnitus Assessment or (OPTINAS) system based on… more
Abstract:To address the Army"s need for an innovative concept for non-invasive, compact, robust monitoring system to monitor the oxidative status of military personnel, ChromoLogic (CL) proposes to develop the OCular Oxidative Stress Monitor (OCOSMO) technology based on non-invasive optical measurements… more
Abstract:The Army seeks a novel and practical approach for the collection and long-term preservation of RNA and other nucleic acids (e.g., microRNA, DNA) from blood products at near room temperature conditions. To address this unmet need, ChromoLogic, LLC, (CL) proposes to develop an Integrated Membrane for… more
Abstract:The parasite Plasmodium vivax, transmitted by the Anopheles mosquito, is the second major cause of malaria worldwide and the major cause of malaria outside Africa. The infection is characterized by a chronic course of malaria with acute episodes of relapse after months to years of asymptomatic… more
Abstract:DESCRIPTION (provided by applicant): Although there are ~300,000 to 600,000 individuals in the United States with active uveitis, there is no clinically accepted method for quantitative assessment of ocular flare that would result in rapid, non-invasive diagnosis of uveitis. Current methods of… more
Abstract:DESCRIPTION (provided by applicant): Type 1 Diabetes (T1D) affects more than 1 million people in the United States Source ADA http://www.diabetes.org/about-diabetes.jsp and is usually diagnosed in children and can lead to blindness, heart disease and kidney failure. A major focus of intervention… more
Abstract:DESCRIPTION (provided by applicant): The proposed work will result in a characterized prototype instrument that will facilitate the identification of a broad range of analytes in small volumes of human blood, urine, saliva and other readily obtainable biological fluids with little sample preparation… more
Abstract:DESCRIPTION (provided by applicant): The objective of this Phase I SBIR proposal is the development of a novel instrumentation platform based on Surface Plasmon Resonance (SPR) that if validated would greatly increase the utility of this label-free technology to researchers utilizing high-content… more
Abstract:DESCRIPTION (provided by applicant): Polymicrobial infections are of great concern to the research community because they have a dramatic impact on the productivity research groups, on the reliability of experimental results, and on the progress that can be made in unraveling fundamental biological… more
Abstract:In Phase II, Solute Consulting will produce a prototype robust collaboration capability for Navy Command and Control,"Navy Wave"with the following technical objectives: 1 - Implement and demonstrate a federated, multi-server, Navy Wave prototype, 2 - Simulate Disconnected, Intermittent,… more
Abstract:The US military has a need for a navigation system to support precision approaches using equipment installed and resident on tactical aircraft. Ideally, modifications to the installed equipment would be limited to software updates. Solute"s approach focuses on modifying the integrity software… more
Abstract:Advances in secure virtualization provide the potential to deliver the benefits of virtualization enjoyed by commercial sector to the security-critical networking domain. While traditional virtualization technologies do not provide a sufficient level of trust to be used in security-critical… more
Abstract:This Small Business Technology Transfer (STTR) Phase II project will optimize the technology developed in Phase I for the fabrication of composite carbon nanofibers incorporating mesoporous high surface area carbon as an electrode material for supercapacitors utilizing ionic liquid electrolytes. The… more
Abstract:ABSTRACT: The goal of this Small Business Innovative Research project is to predict the ability of human listeners to detect and identify specific auditory targets within complex, real-world sound environments. Previous approaches, based on linear auditory models, have produced mixed results. Our… more
Abstract:ABSTRACT: The proposal outlines work and time tables associated with finalizing the development of wear model concepts developed in Phase I work to predict the wear of two materials sliding with respect to each other while being subjected to high velocities and/or high pressures. In parallel with… more
Abstract:This Small Business Innovation Research Phase I project investigates the properties of mesoporous silicate nanoparticles and the use of these particles as non-toxic, char-forming flame retardants (FRs) for thermoset and thermoplastic polymers. The project elucidates the relationship between the… more
Abstract:This Small Business Innovation Research Phase I project is developing novel high flux, compaction-resistant and durable polymer mesocomposite membranes for sustainable drinking water purification and water reuse. The new membranes exhibit 1) superior resistance to internal damage and pore compaction… more
Abstract:ABSTRACT: Clear Science Corp. and Princeton University propose to develop a computational framework for accurately and efficiently modeling the full set of physics associated with aircraft operations. The critical attributes of the proposed framework are accuracy, computational efficiency, and… more
Abstract:DESCRIPTION (provided by applicant): The dire implications of the adult obesity epidemic grow worse over time. Despite front page coverage and universal agreement that the epidemic in weight gain and secondary disease establishment must be addressed, the problem continues. Intended Impact: We… more
Abstract:DESCRIPTION (provided by applicant): Step2 CS Training in Alcohol Addiction and the Medical Consequences of Alcohol This project will create a website, WebOSCE.com, to provide a unique training opportunity for medical students to: 1) prepare for the USMLE(R) Step 2 CS (Clinical Skills) examination,… more
Abstract:DESCRIPTION (provided by applicant): An estimated 116 million US adults suffer from chronic pain at an estimated cost of 635 billion and, unfortunately, existing pain management training is not adequately preparing health professionals to address this area . Opioid prescription drugs, obtained… more
Abstract:DESCRIPTION (provided by applicant): An estimated 116 million US adults suffer from chronic pain at an estimated cost of 635 billion and, unfortunately, existing pain management training is not adequately preparing health professionals to address this area . To address this gap we propose to… more
Abstract:Project Goal/Intended Impact: To improve outcomes of in-treatment addicted patients by providing a virtual reality game as part of a regular health care visit with a health care provider. The game can be played with an off-the-shelf commercially available gaming system (Microsoft Xbox Kinect)… more
Abstract:DESCRIPTION (provided by applicant): This SBIR project is a collaborative effort between AC Diagnostics, Inc. and the University of Pennsylvania to develop and demonstrate a novel diagnostic system for automated on-site detection of viral pathogens in biomedical laboratory animals. Microbial… more
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