Abstract:A novel yet mature technique will be used to assimilate coherent-source multistatic ASW data obtained from drifting acoustic sources and receivers. We will demonstrate the technique's ability to correctly estimate the locations of drifting buoys from acoustic data only even when the buoys may… more
Abstract:This Small Business Innovation Research Phase II project aims to extend work in developing computational music systems that will automatically analyze and re-synthesize digital music for the purpose of transforming a linear and passive music listening practice into an interactive, expressive and… more
Abstract:ABSTRACT: Chiaro Technologies and the University of Colorado will prove the feasibility and investigate the capabilites, limitations, and extensions of the HOlographic Range-doppler processor for Ubiquitous radar Systems (HORUS) in this Phase II STTR. HORUS encodes the signals from a… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project will continue the development and commercialization of spider silk fibers commenced in the Phase I effort. Spider silk is a unique material in nature that is currently inaccessible on a commercial scale. Spider silk and other protein… more
Abstract:This Small Business Innovation Research Phase-II project develops advanced technology capabilities for constructing and deploying client-adapted automated language translation systems within commercial settings that are used by globalizing enterprises and the language service provider companies… more
Abstract:Ocean Pacific Technologies (OPT) is proposing to further develop a high pressure pump and energy recovery device uniquely suited for shipboard seawater reverse osmosis (SWRO) systems. The proposed device will require a unique integration of pumping and energy recovery technologies that are not… more
Abstract:BOT proposes project codenamed DTRAcrete an innovative FR UHPC that is industrial-scalable for low-cost, locally-sourced, fast production, cast-in-situ, deployable for various regions/countries with US military presence. These are the showcased features: Economized materials DTRAcrete will… more
Abstract:Yan Engines proposes to deliver a prototype demonstration engine to the DoD. The engine will have been dynamometer tested against the baseline engine to compare fuel efficiency, torque and emissions profiles for the same power output. Computer-Aided Engineering (CAE) will be used to optimize… more
Abstract:The Liquid Robotics Team proposed to adapt LRI's wave-based propulsion technology and AD & D, Inc. and Ultra USSI's DWADS sonar technologies to create a Persistent Anchorless Active Sonar Craft. Using a combination of conventional fossil fuel and wave-based propulsion, the PAASC will… more
Abstract:The primary objective of our proposed Phase II effort is to develop a centralized multi-vehicle coordinated autonomy framework for the control of large numbers (10"s to 100"s) of SHARC (or other) unmanned surface vehicles to enable execution of several military, commercial, and science… more
Abstract:Mine Countermeasures (MCM) missions of tomorrow will increasingly exploit autonomous vehicles such as the remote multi-mission vehicle to reduce risk to personnel and equipment. However, existing approaches are limited for continuous sensing and planning needed to deal with the dynamic and uncertain… more
Abstract:ABSTRACT: In this proposal, SK Infrared LLC (SKI), a spin off from the Krishna Infrared Detector (KIND) laboratory at the University of New Mexico, is teaming up with Raytheon Vision System (RVS) to develop a flat top broadband high operating temperature mid wave infrared and long wave infrared… more
Abstract:BST Systems has been engaged in IR & D Projects #7079, #7103 and SBIR Phase I Topic #N101-054 targeting sealed-cell operation, separator improvement, and negative electrode enhancement. The aim is to develop a nearly maintenance-free, sealed-cell that offers overall performance improvement in… more
Abstract:Samarium-153 (153Sm) has ideal nuclear properties for a variety of therapeutic applications; however, it is only available in low specific activity (radioactivity/weight) form. While large quantities can be made by the 152Sm(n,)153Sm reaction in a medium flux reactor such as at the University… more
Abstract:DESCRIPTION (provided by applicant): Type 2 diabetes mellitus is one of the most challenging health problems of the 21st century. Global health care expenditures to treat diabetes and its complications are estimated to have been 376 billion in 2010, of which 198 billion was spent in the United… more
Abstract:NanoPlatelets (NPs) created of metal hydroxides present entirely new and previously unknown set of morphologes/properties and are a virtually new frontier and unstudied field of Material Science and may be leveraged into many of todays DoD and Comercial Technical Challenges and applications. Case in… more
Abstract:DESCRIPTION (provided by applicant): The study of retinoblastoma, a childhood tumor, has provided numerous insights into cancer biology. Perhaps most significantly, this work has revealed that cancers can develop in response to mutations in tumor suppressor genes. Tumor suppressor mutations account… more
Abstract:Constitutively activated forms of ALK caused by genetic aberrations have been shown to cause an expanding variety of human cancers. The FDA recently approved the Pfizer drug Xalkori (crizotinib) to treat patients with non-small cell lung cancers (NSCLC) that express ALK. Numerous other… more
Abstract:Lung cancer is the main cause of cancer mortality worldwide with 80% non-small cell lung cancer (NSCLC) in type and mainly driven by three mutually exclusive oncogenes, EGFR, KRAS and ALK (collectively between 30-60% of all NSCLC cases). Oncogenic driverssuch as ROS1 and RET fusions and DEPDC1… more
Abstract:DESCRIPTION (provided by applicant): This Phase I SBIR will develop ICPCheck, the first long term implantable, non-invasively readable intracranial pressure (ICP) monitor for hydrocephalus patients. This device will result in improved clinical management of hydrocephalus by providing a rapid and… more
Abstract:DESCRIPTION (provided by applicant): In recent years there has been increased interest throughout the world in the use of proton radiation therapy for treatment of cancer. Currently, there are only 9 operational centers in the US that treat a total of about 7,000 patients per year comprising less… more
Abstract:DESCRIPTION (provided by applicant): The problem of overweight children with intellectual disabilities (ID) has many adverse medical and psychological effects and is of growing concern among professionals in the disability research and advocacy arenas. Toaddress this issue, we propose to develop… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project seeks to increase the cycle life of cathode materials used in lithium-ion batteries by a factor of ten in high-temperature applications by applying protective nanoporous ceramic coatings. SolRayo will investigate the effects that… more
Abstract:This Small Business Innovation Research Phase I project will demonstrate a more effective and economical process for extracting the chemical and energy resources from lignocellulosic biomass. Existing lignocellulosic pretreatment technologies use any of a variety of chemicals, heat, and mechanical… more
Abstract:ABSTRACT: AuraSense is developing and commercializing NanoFlare technology as an enabling tool for detecting RNA levels in cells. Current methods for sensing of viral exposure require great amounts of virus particles to be present in blood, or extensive processing of blood to isolate virus-specific… more
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