Abstract:The proposed effort has the objective to develop a method for representing the influence of surface roughness on turbulent transport. The method is designed for highly non-equilibrium flows, as occurs on helicopter rotors, and in other engineering applications. It is based on the displacement of… more
Abstract:ABSTRACT: Two optical methods are proposed for the detection of a range of types of damage on coated and uncoated airfoils in advanced gas turbines by means of borescope inspection of on-wing parts. The techniques are low coherence interferometry imaging of bulk TBC optical properties and… more
Abstract:In response to the Army"s requirement for new instrumentation for the quantitative evaluation of the whole-field dynamic response of ballistic impacted specimens, MetroLaser proposes a multi-beam laser velocimeter that will measure the time history of velocity and displacement at 8x8 points of… more
Abstract:ABSTRACT: The goal of this effort is to develop a physics-based model and simulation capability for MIMO radar clutter that accurately characterizes the statistical and spectral properties of the clutter under a variety of operating conditions. Our clutter patch model will be capable of predicting… more
Abstract:Optimistic processing is the key enabling technology for parallel performance of major MDA M & S projects ever since the Synchronous Environment for Emulation and Discrete Event Simulation (SPEEDES) was introduced to the MDA in 1997. However, writing rollbackable models as required for… more
Abstract:This proposal describes a principled approach based on a proven technology base that unifies DCL Information Processing (IP). Our approach incorporates prior environmental information (e.g., spatial-temporal clutter map, sound speed, etc.) and adapts to in-situ environmental information to account… more
Abstract:The torpedo threat to U.S. and coalition naval forces is real and growing. Incorporating machine learning into the fire control piece for the Torpedo Warning System (TWS) can help to increase the probability of kill for the large number of possible torpedo threats. Metron, Inc. proposes a unique… more
Abstract:The opportunity presented under this program is to develop next-generation fuel-sealing technology that can be applied to impart self-sealing capability to the most vulnerable areas of integral aircraft fuel tanks. Targeted application of the self-sealing materials will reduce the weight and fuel… more
Abstract:ABSTRACT: The Hill AFB Industrial Water Treatment Plant typically uses metal hydroxide precipitation to remove heavy metals from the waste stream. However, there are numerous chemicals found in common cleaners and other products in the wastewater that interfere with the precipitation process,… more
Abstract:Solar shading is used by the military in many different field applications as a cost effective approach to reduce fuel consumption for climate control in expeditionary shelters. These relatively simple, low cost shades offer one of the most significant energy saving solutions for expeditionary… more
Abstract:The objective of this program is to develop and demonstrate a bladder storage and delivery system to supply reactants used in air independent propulsion systems. The system design will be adaptable to a variety of reactant types and propulsion systems (e.g., meet capacity, flow and pressure… more
Abstract:METSS proposes to develop its flaccid liner approach for fuel/oxidizer delivery systems used in UUV energy sections. A key element is the use of unstressed bags constructed from polymeric materials that are compatible with the liquid reactants required by the power plant. The system is initially… more
Abstract:ABSTRACT: Michigan Aerospace Corporation, in cooperation with the University of Michigan"s Department of Atmospheric, Oceanic, and Space Sciences, will refine existing upper atmospheric models and apply them to the problem of predicting satellite drag. The primary goal of this Phase 1 project… more
Abstract:Michigan Aerospace Corporation (MAC) proposes to advance NASA's nonintrusive spatially- and temporally-resolved Interferometric Rayleigh Scattering (IRS) technology to perform additional multiple properties measurements in high-speed flows. In particular, an instantaneous nonintrusive Optical… more
Abstract:During this Phase I, Michigan Aerospace Corporation will adapt the design of an optical MEMS seismometer for lunar and other planetary science instrumentation. The optical MEMS based seismometer takes advantage of the high Q of morphological dependent resonances and can be sensitive to a few nano-g… more
Abstract:Gas turbine engine technology is constantly challenged to operate at higher combustor outlet temperatures. In a modern gas turbine engine, these temperatures can exceed the blade and disk material limits by 600¿F or more, necessitating both internal and film cooling schemes in addition to the use… more
Abstract:Turbine engines can significantly reduce fuel consumption by using a recuperator to heat compressor discharge air with heat from combustion exhaust gases. This increased fuel efficiency is offset by the weight and pressure losses added by the recuperator, so these must be minimized, especially for… more
Abstract:DESCRIPTION (provided by applicant): Our goal is to develop small molecule inhibitors that target influenza entry. In Phase I, we identified several compounds that selectively inhibit the hemagglutinin (HA) mediated virus entry process. Three HA specific entry inhibitors (MBX494, MBX994, and MBX726)… more
Abstract:DESCRIPTION (provided by applicant): The human herpesviridae family contains eight members divided into three subfamilies, designated alpha, beta and gamma. The alpha herpes viruses include herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2) and varicella zoster virus (VZV). The… more
Abstract:DESCRIPTION (provided by applicant): Staphylococcus aureus is a major cause of community and hospital-acquired infections of the skin, soft tissue, and bloodstream. The recent dramatic increase in occurrence of strains resistant to beta-lactam antibiotics(MRSA) has reduced therapeutic options… more
Abstract:DESCRIPTION (provided by applicant): The increasing prevalence of multidrug resistant infections caused by Gram-positive pathogens, such as methicillin resistant Staphylococcus aureus (MRSA), underscores the clinical need for novel strategies to treat life-threatening infections. New antibacterial… more
Abstract:DESCRIPTION (provided by applicant): The overall objective of this project is to further develop a novel chemical class of tuberculosis (TB) therapeutic agents, the spectinamide series, for use against MDR and XDR strains of Mycobacterium tuberculosis (Mtb) and identify, through a series of in vitro… more
Abstract:DESCRIPTION (provided by applicant): Infections caused by multi-drug resistance (MDR) Gram-negative pathogens are becoming increasingly difficult to treat, resulting in increased frequency of treatment failure and mortality. The increasing prevalence of MDR Gram-negative pathogens presents an… more
Abstract:DESCRIPTION (provided by applicant): The overall objective of this project is to generate new, potent, selective antimalarials that act through a novel mechanism of blocking the plasmodial surface anion channel (PSAC), a previously unexploited and highly conserved plasmodial target. Human malaria is… more
Abstract:DESCRIPTION (provided by applicant): Dental caries, commonly known as tooth decay, is a serious health problem all over the world, and is one of the most common infectious diseases in humans. Dental plaque, a biofilm community growing on the tooth surface,can harbor organisms that cause dental… more
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