Abstract:One of the principle challenges in developing a robust missile defense architecture is the characterization and classification of objects in a threat complex. The Ballistic Missile Defense System (BMDS) performance depends on data from diverse EO/IR and RF sensors. The objective of this proposal… more
Abstract:The task of managing employment planning and real time tasking of sensor resources in complex ballistic missile defense target environments demands innovative techniques. As the complexity of a threat scene grows, the resources required to survey the situation grow at an even faster rate. Sensor… more
Abstract:ABSTRACT: As satellite technology has become increasingly pervasive in both our military warfighting capability and civilian society, the ability to determine and forecast space environmental impacts on these satellites is critical. AFRL, NOAA and NASA have been nowcasting and forecasting space… more
Abstract:The proposed Phase II.5 work builds upon previous Phase II work for this SBIR program. MTSI will perform several tasks during the Phase II.5 program to extend the previous work and increase the Technology Readiness Level (TRL) to TRL 5. The previous Phase I and Phase II work applied probabilistic… more
Abstract:Accurate assessment of burn size, depth and the compromise of normal tissue physiology, as well as the tracking of wound response, is essential for successful treatment of burns and one of the major problems that face clinicians and surgeons. The primary method of burn wound assessment is subjective… more
Abstract:DESCRIPTION (provided by applicant): Diabetes mellitus affected 285 million adults worldwide in 2010 and is expected to increase in prevalence to 439 million people by the year 2030. Foot ulceration continues to be a major comorbidity of diabetes and afflicts as many as 15 to 25% of subjects with… more
Abstract:ABSTRACT: We propose to develop an assured information sharing framework for cloud-based systems that leverages our ongoing work in the areas of policy-based usage management and semantic interoperability. The development of this framework will involve the creation of a novel approach to… more
Abstract:Modus Operandi proposes to develop Inception, a collaborative intelligent wiki for searching, gathering, interpreting, validating, capturing and documenting the characterization of stakeholder needs for Modeling and Simulation systems. The first phase or the inception phase of the systems… more
Abstract:ABSTRACT: A nightmare scenario for the U.S. Air Force is where multiple satellites suddenly stop communicating without warning, indicating a possible hostile anti-satellite campaign on the nation"s space assets. In order to mitigate this significant national risk, the Air Force Space Command… more
Abstract:Navy operators are being inundated with intelligence information, especially text. Better methods and tools are needed to help them identify the mission-relevant"needles"within these information"haystacks."Researchers have made progress using ontologiesrepresented as RDF… more
Abstract:Modus Operandi proposes the development of the Semantic Targeting and All-source Fusion Framework (STAFF), an innovative, net-centric framework for fusing human intelligence (HUMINT), video and imagery intelligence (IMINT), signals intelligence (SIGINT), and other intelligence data for high-value… more
Abstract:Early identification of indicators or behaviors of adversarial intent is critical to protecting US soldiers from attack during counter-insurgency and peace-keeping missions. Furthermore, the enemy goes to great lengths to hide his activities, making detection even more difficult. Modus Operandi… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project is directed towards the development of an ultrahigh speed micro-spindle for micro-machining. The proposed spindle for micro-milling and micro-grinding at speeds near 500,000 rpm will be implemented with existing commercial… more
Abstract:ABSTRACT: The overall objective and scope of this proposed effort includes determining bearing requirements for a high performance 1000 lbf thrust class gas turbine engine; a review of materials suitable for extreme environment bearings; preliminary trade studies to assess thrust bearing design;… more
Abstract:DESCRIPTION (provided by applicant): This competitive renewal SBIR proposal extends our current Phase II translational research on novel synthetic lipid/peptide lung surfactants containing the highly active Super Mini-B (S-MB) peptide incorporating crucialfunctional regions of human surfactant… more
Abstract:DESCRIPTION (provided by applicant): The overall goal for this SHIFT SBIR application is to develop new, easy-to-use conjugatable adjuvant lipid vesicle (CALV) kits which contain Toll-like Receptor (TLR) agonists 3 and 7/8. Utilizing our proprietary VesiVax(R) CALV system and the Bacillus anthracis… more
Abstract:DESCRIPTION (provided by applicant): The overall goal of this SBIR AT application is to develop a multi-adjuvant liposomal vaccine formulation that targets dendritic cells and can be applied to our current vaccine programs. The innovation is a dual adjuvant system where VesiVax(R) lipid vesicles are… more
Abstract:DESCRIPTION (provided by applicant): A kit based PET agent: edotreotide Ga 68 for clinical imaging of somatostatin receptor expressing tissue. Synthetic peptides targeted to Somatostatin receptors (SSTR) were developed almost 30 years ago by Novartis to inhibit the effects of endogenous growth… more
Abstract:DESCRIPTION (provided by applicant): We propose to develop a software package to automatically evaluate a subject's beta amyloid PET scan (using either C11-PIB, F18-florbetaben, or F18-florbetapir, F18-flutemetamol) by normalizing the subject's scan, masking away non-gray matter tissue… more
Abstract:DESCRIPTION (provided by applicant): According to the NIAID fact sheet on Botulism, the extreme toxicity of botulinum neurotoxins (BoNT) and the ease of production, transport, and delivery make this an agent of extreme bioterrorism concern. Nonetheless, although there are major vaccine… more
Abstract:DESCRIPTION (provided by applicant): Although a rapid and accurate diagnosis is crucial to the management of patients suspected of bacterial infection, the currently available radiopharmaceuticals are not capable of distinguishing between sterile inflammation and bacterial infections. Our goal is to… more
Abstract:DESCRIPTION (provided by applicant): Using conservative criteria it is estimated that 7 percent of the population in North America and 7-10 percent worldwide have Irritable Bowel Syndrome (IBS), a relapsing functional bowel disorder with unclear etiology.Disabling symptoms of IBS account for a… more
Abstract:Resodyn Corporation is proposing a material and application system that will create a low friction coating on concrete median barriers. The advanced material developed for the low friction coating is an affordable, tough, weather resistant, and environmentally friendly copolymer. The proposed… more
Abstract:ABSTRACT: The current polyurethane based coatings on the landing skis/skids of US Air Force aircraft require frequent maintenance due to exposure to extreme conditions. A long-lasting, low-friction, hydrophobic, impact and abrasion resistant coating on the landing ski/skids is highly desired to… more
Abstract:The U.S. Navy seeks an in-situ powder coating material and application method for spot repair. Resodyn Corporation proposes a unique restoration and repair polymer thermal spray coating (R & RPTS) system that provides the ease of repair, safety in handling, and effective coating protection to… more
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