Abstract:O-glycosylation is one type of important protein modification and plays crucial roles in many cellular processes. Currently, there is limited commercial source for the glycosyl amino acid building blocks that can be utilized in glycopeptide synthesis. Inthis Phase I project, Life BioScience Inc.… more
Abstract:This proposal describes an innovation for making bulk nanocrystalline tungsten alloys that will be sufficiently ductile and meet mechanical properties targets set by the army. Tungsten (W) and its alloys are primary candidate materials for next generation munitions and warheads owing to its high… more
Abstract:While most media attention in the wake of a terrorist attack, a natural disaster, or even a single building fire focuses rightly on the safety and wellbeing
of the general public, one often overlooked aspect of these catastrophic events is the extreme risk taken by first responders who enter… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project seeks to develop bioactive, high-strength contrast agents for use in orthopedic and bone implant applications. There is a clear clinical need for improved contrast agents that increase the strength, toughness and abrasion wear of… more
Abstract:Effective configuration management allows asset owners and EPC firms to more efficiently manage nuclear projects across the lifecycle of the facility thereby reducing overall costs. However, a key element of configuration management is accurate as-built coordinates and information for the entire… more
Abstract:Organic Light Emitting Diode (OLED) is a new emerging technology that is energy efficient and environment friendly lighting replacement for current lighting technologies such as incandescent bulbs and fluorescent tubes. As performance of OLEDs has improved over the last several years it has… more
Abstract:This Small Business Innovation Research Phase-I project will address the development of modified sophorolipid (MSL) surfactant molecules by simple and scalable modification of natural SLs adopting "green chemistry principles". Natural SLs will be produced through fermentation with yeast… more
Abstract:This Small Business Innovation Research Program (SBIR) Phase I project is aimed at development of a conductometric cell for water quality monitoring that employs properties of polyxoxmetalats (POMs) and their so called lacunary derivatives. The proposed approach is based on measurements of electric… more
Abstract:This Small Business Innovation Research Phase I project is designed to evaluate a novel interphase nanocoating designed for Silicon Carbide (SiC) fibers, which is intended to behave as a biomimetic immune system for high-temperature Ceramic Matrix Composites (CMCs) exposed to an oxidizing… more
Abstract:Ballistic and blast protection of both the crew and vital equipment onboard U.S. Navy surface ships and carriers is a critical component in the design of topside structures on these vessels. Materials such as glass, Plexiglas and polyurea are being considered and implemented for protection in these… more
Abstract:Despite being within the payload capacity of the Medium Weight Shock Machine (MWSM), shock qualification testing of medium weight (500 4500 lbs) Class II equipment must currently be performed through underwater explosion (UNDEX) testing using a Floating Shock Platform (FSP), typically in… more
Abstract:The use of composite materials in Naval structures continues to expand as the materials systems along with their engineering design and analysis capabilities advance. To that end, it is becoming paramount that real-time assessments be made of these materials while they are in-service to ensure… more
Abstract:Ferrite control components including circulators and isolators are fundamental building blocks of Transmit/Receive modules (TRM) utilized in high data rate active space transceivers and transponders for both long-range (LR) and low earth orbit (LEO) systems. These components are utilized to protect… more
Abstract:Over the course of this small business innovative research (SBIR) phase 1 (Ph1) program Metamagnetics proposes the development of next generation ultra-fast and broadband T/R switches with high isolation (>30 dB) based on thin films of vanadium dioxide (VO2) metal-insulator transition (MIT)… more
Abstract:ABSTRACT: The DoD requires increased performance and increased density solid propellants for use on boost, strategic and tactical missile systems, however, simultaneously attaining higher energy and density while maintaining satisfactory physical properties is an extremely challenging goal. Current… more
Abstract:The global market for bio-based chemicals is at a critical stage of development, with focus on new bio-based routes to chemicals and building the type of commercial-scale plants that will enable the market to truly compete with petroleum derived chemicals. The 2011 Frost & amp; Sullivan report… more
Abstract:Today the evaluation methods employed in the development and assessment of soldier borne Personal Protective Equipment (PPE) system designs are often extremely slow, expensive, and subjective, resulting in significant delays and expense in the fielding of improved designs. Recent rapid advancements… more
Abstract:This effort will develop a software tool with the ability for near real-time threat and target area routing and de-confliction capability. Through the use of innovative algorithms based on reactive-navigation, extension of Genetic Algorithm work, and software architecture it will optimize the… more
Abstract:The QED team proposes an Advanced Payload Handling System (APHS) capable of semi-autonomous and/or wireless remotely controlled, omni-directionally maneuvering operations. Selected design candidates will be evaluated with respect to their ability to provide an assured capability of acquiring and… more
Abstract:This Small Business Innovation Research Program Phase I project will demonstrate innovative new technology for high precision, non-contact 3D imaging and metrology with order of magnitude improvement in lateral resolution, depth of field, and measurement speed over existing commercial optical… more
Abstract:This Small Business Innovation Research Phase I project relates to the use of nano-structured chemicals in the processing of light-weight magnesium (Mg) alloys for high performance applications. It is postulated that reactive nano-structured chemicals such as polyhedral oligomeric silsesquioxane… more
Abstract:The US Department of Energy (DOE) has reported that the wave energy resource available in the US has the potential to power over 100 million homes each year, and the DOE is currently developing an aggressive strategy to support its vision of providing 15% of our nations electricity needs from water… more
Abstract:Diesel compression ratios are normally set high (16:1 to 23:1) for cold starting, yet data show optimum fuel efficiency and emissions occur at compression ratios below 14:1. The industry trend has been to steadily reduce compression ratio. Literature findings indicate that reducing Diesel… more
Abstract:Diesel engine manufacturers need a way to improve fuel economy as well as limit NOx and particulate emissions to meet upcoming federal, state, and global regulations. A large percentage of emissions and fuel consumption occurs during cold start and light to medium load operation. EMA proposes to… more
Abstract:Mine countermeasures (MCM) missions require complex coordination of personnel, equipment, and autonomous vehicles. The mission success hinges on timely and accurate decision-making for responding to dynamic situations in the area of operations that pose considerable risks to mission assets; both… more
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