Abstract:The project team is developing a prototype of the Readorium Rising Reader, a web-based game for students in grades 3 to 5 intended to strengthen reading comprehension of non-fiction science text. The game will provide students with strategies to use as they construct meaning and decipher new… more
Abstract:DESCRIPTION (provided by applicant): The goal of the current project is to revise a prototype of a computerized attention training program (Amplified Attention Training, AAT) for hemispatial neglect completed in Phase I, and conduct a multi-site, randomized, controlled trial to establish efficacy in… more
Abstract:DESCRIPTION (provided by applicant): A large body of evidence indicates that the cognitive impairment and delayed neurodegeneration in traumatic brain injury (TBI) is caused by increased accumulation of tau, phosphorylated tau (p-tau) and other neurotoxic proteins including APP and… more
Abstract:DESCRIPTION (provided by applicant): Low back and neck pain are two of the most common medical problems. In a recent study, 26.4% of individuals had an episode of severe low back pain and 13.8% severe neck pain in the preceding 3 months. Moreover, low backor neck pain is the major complaint in 3% of… more
Abstract:DESCRIPTION (provided by APPLICANT): An overlooked, neglected, yet significant problem in the United States today is the use and abuse of tobacco, alcohol, and other drugs by individuals with intellectual disabilities (ID). Increasing numbers of people with ID are living independently in the… more
Abstract:ABSTRACT: Mycotoxins are toxic secondary metabolites of molds and fungi, many of which are pathogenic to humans. In general, mycotoxins enter the body through the skin, digestive tract, or through respiration. Exposure to a few milligrams can be lethal. Mycotoxins have a high likelihood of … more
Abstract:Communication SoC technology has advanced significantly over the past ten years resulting in highly integrated radio SoC chips for standards such as Wi-Fi, global position system (GPS), Bluetooth (BT), 3G cellular, digital TV (DTV), and cable modems. While most radio SoC"s are narrowband (e.g.… more
Abstract:ABSTRACT: Recent demand for broadband satellite communications (SATCOM) has risen sharply for both the defense and commercial sectors. Tactical SATCOM, such as WGS, require increasingly broadband information contents such as high resolution surveillance images and videos, while on the other hand,… more
Abstract:DESCRIPTION (provided by applicant): Yearly influenza epidemics affect about 5 - 15% of the world's population and estimates of annual mortality range from 250,000 - 500,000, including approximately 30,000 deaths and 200,000 hospitalizations in the UnitedStates. In addition, the likelihood of a… more
Abstract:Washburn Therapeutics Inc. is developing biologically active gels that control inflammation by selectively neutralizing pro-inflammatory cytokines based on a technology being licensed exclusively by the company from Carnegie Mellon University. Preliminary results demonstrated that conjugates of… more
Abstract:DESCRIPTION (provided by applicant): A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellarium for treatment of glial cell-based cancers. Successful completion of this project will confirm therapeutic effect and… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes to develop an artificial trachea made from synthetic nanofibers that is seeded with the patient?s own stem cells in the operating room using a disposable, closed system seeding chamber. There currently are no commercially… more
Abstract:DESCRIPTION (provided by applicant): PROJECT SUMMARY This proposal is a Phase 1 proposal in response to The National Institute of Health Small Business Innovation Research (SBIR) Program call for proposals for the Cancer Diagnostics and Therapeutic AgentsEnabled By Nanotechnology (SBIR [U43/U44])… more
Abstract:DESCRIPTION (provided by applicant): Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness in people over age 60 in the developed world. Progression of this disease results in the loss of the ability to perform activitieshighly correlaed with quality of life. This… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project should dramatically improve intersection safety and mobility in a practical way. Safety is measured by the risk of collision between pedestrians, bicycles and vehicles; safety is improved by better signal timing, warnings, and possibly… more
Abstract:DESCRIPTION (provided by applicant): Over one million prostate biopsies are performed in the US each year to diagnose approximately 200,000 cases of prostate cancer. The majority of these biopsies are performed needlessly. The overall objective of this project is to develop a secondary prostate… more
Abstract:Biogas & Electric LLCs proposed Phase I research will strive to demonstrate the existing opportunities for resource recovery and recycling at dairies and other concentrated animal feeding operations (CAFOs). Current recovery efforts are limited to energy from biogas combustion and a few struvite… more
Abstract:The effectiveness of synchrotron radiation science has been hindered by the limited availability of advanced diagnostics. In many cases, the capability to produce photon fluxes has outpaced the ability to detect and measure the resultant photons. Synchrotron applications are becoming more… more
Abstract:This proposal will serve as a pilot project for poor, rural, Southern counties with rich forestry resources. Arkansas and surrounding states have some of the highest poverty rates in the nation. Arkansas 19 million acres of forests represent more than half of the total land mass of this state. This… more
Abstract:In an effort to support the development of a domestic marine aquaculture industry, Zeigler Bros. Inc., (ZBI) proposes to continue its Phase I research by demonstrating the ability to scale up inclusion particle (IP) manufacturing. During Phase II ZBI will also demonstrate the efficacy of IOs for… more
Abstract:The TAU Performance System is a powerful and highly versatile profiling and tracing tool ecosystem for performance analysis of parallel programs. Developed over the last 15 years, TAU has evolved with each new generation of HPC systems and scales efficiently to hundreds of thousands of cores on the… more
Abstract:Currently, the most successful approach for table top soft-Xray and EUV (Extreme Ultra-Violet) sources, is that of High Harmonic Generation (HHG), where a high intensity pulses are used to drive frequency conversion from a noble gas in a hollow core fiber. This configuration allows phase matching,… more
Abstract:With the 4 billion tons of uranium estimated to be dissolved in the earth & apos;s oceans, an essentially unlimited resource is available to those with easy and affordable access. With decades of research towards the extraction of uranium from seawater, focus has been directed towards the… more
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