Abstract:The goal of this project is to design and build a THz-frequency spectrometer prototype with sub-wavelength spatial resolution for use in the spectroscopic and temporal analysis of trace material samples in advanced sensing and monitoring applications. The instrument operating at room temperature… more
Abstract:ABSTRACT: Computational electromagnetics and inverse methods are the foundations of modern methods of eddy-current nondestructive evaluation (NDE). In this project, we apply these methods to the problem of characterizing, in three dimensions, damage in complex aircraft structures. As the… more
Abstract:ABSTRACT: To achieve the objectives of condition-based maintenance plus prognosis (CBM+), and realize its potential, the location and size of damage at any length scale, e.g., either a crack or a microstructural perturbation, needs to be determined with statistical metrics to feed prognostic… more
Abstract:VIP Sensors proposes to develop a very low noise, highly sensitive Fiber Optic Vector Sensor (FOVS) System packaged in a size - A sonobuoy. The FOVS includes a triaxial optical accelerometer, an omnidirectional optical hydrophone and an optical compass. Only a pair of single mode optic fibers… more
Abstract:DESCRIPTION: The objective of this proposal is to attempt a new mode of analysis for biological tissue by matrix-assisted laser desorption ionization imaging mass spectrometry (MALDI-IMS). MALDI-IMS is a powerful analytical technique capable of generating~ 50-100 micrometer resolution images that… more
Abstract:DESCRIPTION (provided by applicant): Mass spectrometry is now established as an essential tool in the biological research laboratory and is widely used for characterizing clinicaly significant peptides and proteins. However, more than twenty years after the advent of the enabling approaches of… more
Abstract:VDI and OSU are in a strong position to meet the requirements of this SBIR. Building on a strong foundation of closely related sensor work in the millimeter/submillimeter, we will focus our Phase I efforts on the new challenges of this SBIR topic. The chief new analysis challenge is to provide a… more
Abstract:DESCRIPTION (provided by applicant): An increasing variety of diseases are being shown to be due to immunological processes, including diabetes, and now Alzheimer's disease (AD). AD is the most prevalent age-associated disease and growing evidence suggeststhat aspects of the innate immune… more
Abstract:DESCRIPTION (provided by applicant): A major goal expressed by NIAID and other agencies charged with development of the U.S. biodefense research strategy is a broad spectrum activity that mitigates catastrophic biothreats across a wide spectrum of agents.Such therapeutic activities have been… more
Abstract:A coupled CEM and CFD modeling is proposed for prediction of antenna performance in plasma environment with particular application to reentry vehicles. The degree of coupling between the fluid dynamics and the electromagnetics will be investigated as well as identification of the parameters that… more
Abstract:Virtual EM is proposing to employ multi-core CPU and GPU acceleration for orders of magnitude increase in computation speed in predicting Co-site Interference among antennas on aircraft and other complex structures. The computational engine utilizes method of moments for accuracy.
Abstract:A prototype Computer Aided Design (CAD) software will be developed for predicting Radar Cross-section (RCS) of various targets of interest to MDA. The software will have an advanced computational engine, which will be optimized to run on Graphical Processing Units (GPUs) and multi-core Central… more
Abstract:DESCRIPTION (provided by applicant): The proposed project, titled Reduce the Risk: An Affect Management Program for HIV Prevention, will examine the use of immersive virtual reality technology as an intervention tool for HIV Prevention with adolescents. Adolescents are at risk for contracting HIV.… more
Abstract:DESCRIPTION (provided by applicant): Pediatric Food Allergy (FA) is recognized as a serious public health concern that affects approximately 4-8% of children, with symptoms affecting multiple organ systems, including skin, the respiratory tract, and the GItract. Food-induced anaphylaxis, which is a… more
Abstract:DESCRIPTION (provided by applicant): Insufficient sleep in children is recognized by Congress and the Department of Health and Human Services as a high priority target for clinical scientific investigation given its consist link with enduring physical, emotional and behavioral problems, including… more
Abstract:DESCRIPTION (provided by applicant): Adolescents in mental health treatment are at greater risk for HIV and other STIs than their peers due to an earlier age of onset of sex, less protected sex, more sexual partners, and more frequent substance use. This greater risk is due to multiple factors… more
Abstract:DESCRIPTION (provided by applicant): Since its introduction in the 1960's, fluorescein angiography (FA) has been the gold standard for retinal vascular diagnosis. However, FA is costly, invasive, and time-consuming, which limits its usefulness as a screening tool. As a potential non-invasive… more
Abstract:DESCRIPTION (provided by applicant): According to the National Institutes of Health, there are more than 80 million people in the US who suffer from a potentially sight-threatening disease. Doctors see seven to eight million new cases of eye disease annually. More than two million Americans age 50… more
Abstract:The research proposed under this effort is focused on addressing the need for improved real-time in-situ sensing approaches for monitoring radionuclide contamination in the soils surrounding waste disposal facilities. Specifically this proposal focuses on the development of an approach for detecting… more
Abstract:Aerosol research remains a priority area and requires strong efforts to resolve the very complex processes that occur in the atmosphere. To understand aerosol formation and their implications on climate the study of precursors provides very valuable information. Ammonia is one of the most… more
Abstract:Aircraft On-Board Oxygen Generating System (OBOGS) selectively filters compressed air from the aircraft's engine to remove nitrogen and other gaseous contaminants to provide the aircrew with an oxygen enriched breathing gas. During shipboard operations, Navy aircraft are particularly vulnerable… more
Abstract:DESCRIPTION (provided by applicant): We synthesized a recombinant version of Mimivirus (MV) DNA topoisomerase 1B protein possessing an unusual 5'OH ligation activity (MV-ligase). This permits a novel type of probe for the detection of apoptotic cell clearance. In this project w will develop… more
Abstract:DESCRIPTION (provided by applicant): The purpose of this SBIR project is to develop a new tool to improve the ability of blind and visually impaired people to quickly get to the right web pages, to avoid ending up on the wrong web pages, and to reach the desired part of each web page efficiently.… more
Abstract:Renewable energy generation is one of todays most challenging global dilemmas. The energy crisis requires tapping into every source of energy and developing every technology that can generate energy at a competitive cost within the next 50 years. Development of the FiSH-MHK transformative technology… more
Abstract:The successful results of the Phase I work will be utilized by implementing an optimized ultra-short pulse Optical Parametric Chirped Pulse Amplifier at an eye safer Short Wave InfraRed (SWIR) wavelength. The system will be designed with a goal of 1 kHz repetition rate and will ultimately reach a… more
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