Abstract:DESCRIPTION (provided by applicant): KDH Research and Communication (KDHRC) proposes to develop Cochlear Implant University (CIU) website, a self-advocacy training tool for high school and college students with CIs (SWCIs) aged 16 to 21 and their parents to develop self-advocacy knowledge and skills… more
Abstract:DESCRIPTION (provided by applicant): KDH Research and Communication (KDHRC) proposes to develop and evaluate Dientes Fuertes, Vida Sana (DFVS), a culturally-competent program to prevent primary tooth decay in low-income Latino children ages zero to six. Toeffectively reach low-income Latino children… more
Abstract:DESCRIPTION (provided by applicant): The objective of this Fast Track Small Business Innovation Research (SBIR) application, submitted by KDH Research and Communication (KDHRC), is to develop and evaluate the School TIME Toolkit (Toolkit) to support parents and teachers of elementary school-aged… more
Abstract:A system to automatically identify mission-relevant information within modern tactical databases, score them relative to current mission state, and transmit the most important elements in a timely manner to small unit leaders and other decision elements subject to the constraints of both human and… more
Abstract:DESCRIPTION (provided by applicant): The C-PACE Project (Communications Processes for Accountable Care Enhancement) will develop a new and innovative form of social computing that is customized for the care of frail, elderly patients. A successful C-PACE system will improve patient-centered health… more
Abstract:Looking Glass is an immersive, story-driven game experience that enables computer science education for students K-12. It presents learning in a game-based series of challenge levels that permit a high degree of player choice in tailoring educational progression and adapting game systems that… more
Abstract:S34A, Inc. proposes to build upon our successful Phase I R&D effort and commence the development of an integrated hardware, software, and service
solution that facilitates the extraction of forensic data from SSDs - data that resides outside the Logical Block Address (LBA) space and is not… more
Abstract:Kappler proposes to further define and develop a novel fabric composite that when integrated into Personal Protective Equipment (PPE) garments,
provides protection to the wearer from multiple threats. The proposed research builds on the strength of the Phase I effort where Kappler validated
the base… more
Abstract:This research program develops and demonstrates a ranging method capable of GPS-like accuracy (less than 3 m RMS error) using signals compatible with GSM cellular networks. The method operates without interference with GSM service and can be implemented using standard cellular hardware components.
Abstract:DESCRIPTION (provided by applicant): A policy statement by the World Health Organization notes that, the male latex condom is the single, most efficient, available technology to reduce the transmission of HIV and other sexually transmitted infections. Unfortunately, despite decades of condom… more
Abstract:Abstract There is an unmet need for cost-efficient technologies for high purity isolation of rare circulating tumor cells (CTCs) from blood. An ideal isolation technique should be able to meet the following criteria: (a) minimal processing time; (b) low final sample volume; (c) isolation from large… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project proposes to develop a high-throughput, multi-analyte chromatin immunoprecipitation (ChIP) assay. ChIP is a widely used technique among life science and biomedical researchers seeking to understand how the epigenetic mechanism of histone… more
Abstract:This Small Business Innovation Research Phase I project pertains to the development of polymer hydrogel-based time temperature indicators (TTIs) to monitor the temperature history of individual vaccine vials. Certain vaccines suffer irreversible loss in potency if exposed to cold temperatures below… more
Abstract:Advanced infrared imaging (night vision) equipment forms a critical component of the US military's tactical capabilities. The development of new third-generation, multi-wavelength infrared focal-plane arrays (FPAs) promises to enhance the superiority of the US military by providing improved… more
Abstract:DESCRIPTION (provided by applicant): Neuropeptide somatostatin analogs are important therapeutics for the treatment of hormone secreting tumors with annual sales of ~ 1.7B. However, the currently available peptide depots are effective in only half the patients with growth hormone secreting tumors,… more
Abstract:DESCRIPTION (provided by applicant): Noroviruses are a group of enteropathogenic viruses belonging to the taxonomic family Caliciviridae, which causes approximately 90% of epidemic non-bacterial outbreaks of gastroenteritis around the world and may be responsible for 50% of all foodborne outbreaks… more
Abstract:SpeakAgent is a non-instructional, multimodal, game-based approach to naturally acquiring foreign languages that applies recent findings in neurolinguistics and second language acquisition theory. It seeks to maximize auditory input and imbue it with relevance and meaning in the game context,… more
Abstract:DESCRIPTION (provided by applicant): Alzheimer's disease (AD) is a progressive and ultimately fatal neurodegenerative disease that affects more than five million people in the USA. Currently there is no cure for AD. Available medicines are aimed only at temporarily reducing symptoms and slowing… more
Abstract:ABSTRACT: Optical refrigeration is currently the only demonstrated all-solid-state cryocooling technology. Optical cryocoolers are devices that use laser light to cool small crystal or glass cooling elements. The cooling element absorbs the laser light and reradiates it at higher energy, an example… more
Abstract:We propose to design, build and analyze Massively Redundant Electromechanical (MREM) Actuators based on multilayer, electrostatic motors. The key element is combining many wafer-scale components to produce a highly reliable large-scale actuator. The device consists of many individual actuator… more
Abstract:DESCRIPTION (provided by applicant): Epilepsy is a serious and costly neurologic condition that affects approximately 3% of the US population, and is often both costly and difficult to diagnose. Presently, a physician's diagnosis is based on a combinationof the physician's clinical… more
Abstract:Design, prototype and test Magnetic Resonance Imaging (MRI)-conditional myocardial biopsy forceps catheters and test and demonstrate the feasibility of candidate devices in phantoms and in an animal model. Document the device s specifications, operations,assembly procedures, protocol for use, MRI… more
Abstract:DESCRIPTION (provided by applicant): Synthetic modification of a natural toxin, gonyautoxin 2/3, is enabling the development of new therapies for painful neuromuscular disorders, such as anal fissure and chronic tension-type headache. Gonyautoxins target voltage-gated Na+ ion channels, a family of… more
Abstract:DESCRIPTION (provided by applicant): Side effects associated with opioid analgesics, such as nausea, drowsiness, respiratory depression, and potential for addiction, are motivating the design and development of new therapies for acute, subacute and chronic pain. Voltage-gated Na+ ion channels are… more
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