Abstract:The innovation of network forecasting is a new approach to securing industrial control networks that is based upon 1) discovering, monitoring, and modeling all devices on a network, 2) using these models to predict future device behavior, 3) evaluating past predictions with current observations of… more
Abstract:DESCRIPTION (provided by applicant): Despite remarkable advances in cancer detection and treatment, the disease continues to be a leading cause of mortality in the US accounting for 23% of all deaths in 2011. Cancer of the breast and prostate are by far the most common forms diagnosed in US women… more
Abstract:DESCRIPTION (provided by applicant): Chronic obstructive pulmonary disease (COPD) is a highly and increasingly prevalent disorder characterized by incomplete reversible airflow limitations. It is presently the third leading cause of death in the US, with over 13 million peopl suffering from the… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will investigate the technical and commercial feasibility of designing a video-based roof surveying software. Roof surveying is an essential activity in sheet metal roofing projects. Several technologies have been evolved over the years… more
Abstract:DESCRIPTION (provided by applicant): Heart failure following a myocardial infarction (MI) continues to remain a leading killer in the western world. In the United States, the estimated annual incidence of myocardial infarction (MI) is 745,000 new and 410,000 recurrent episodes. There is a critical… more
Abstract:DESCRIPTION (provided by applicant): Accurate measurement of core body temperature during surgery as well as in critical care is imperative to a positive outcome and ongoing quality of life for patients. Core temperature management of patients during extended anesthesia such as cardio-pulmonary… more
Abstract:The goal of this application is to synthesize heparan sulfate (HS) library consisting of structurally homogeneous oligosaccharides, in response to a SBIR contract call from NCI- 321 Chemically Defined Glycan Libraries . Glycan Therapeutics is a company specializing in the synthesis of structurally… more
Abstract:DESCRIPTION (provided by applicant): For most Americans, understanding and planning a healthy daily menu can be a confusing and multi- faceted process. The cognitive challenges faced by people with intellectual disabilities (ID) create even greater barriers in understanding the complexity of… more
Abstract:Breast cancer is the most common cancer type among women. Approximately one in every eight women is diagnosed with breast cancer at some time in their life and 30% to 40% of the women who get breast cancer die. Early and accurate detection is viewed asthe best method to decrease breast cancer… more
Abstract:The current emphasis in fish nutrition is fish meal replacement with a variety of alternative protein sources including plant-based, terrestrial and marine proteins. We propose to focus specifically upon the protein quality of these alternate protein sources and its potential impacts on marine fish… more
Abstract:DESCRIPTION (provided by applicant): We propose a novel and competitive urinary tract silicone Foley catheter made from a proprietary polymeric formulation to effectively reduce catheter-associated urinary tract infections (CAUTI) via nitric oxide (NO) release. Preliminary studies show that the… more
Abstract:DESCRIPTION (provided by applicant): We propose a novel and price competitive Tunneled Dialysis Catheter (TDC) made from a proprietary polymeric formulation to effectively reduce TDC dysfunction via long-term nitric oxide (NO) release, particularly duringthe period of AVF maturation in incident… more
Abstract:Transit Agency Information required for managing Service centers on resources and assets that need to be available to operate the transit service as designed. An opportunity exists to design an Integrated Framework providing Service delivery and Maintenance Management Information to quantify the… more
Abstract:Evaluation of the Antigenicity of Black-Restricted Haplotypes of Factor VIII ABSTRACT About 30% of congenital Hemophilia A (HA) patients develop alloantibodies that neutralize the activity of replacement Factor (F) VIII proteins. Such patients, who are termed inhibitor patients, are typically… more
Abstract:DESCRIPTION (provided by applicant): Feasibility of a nerve imaging agent to reduce neurological complications of prostatectomies A key challenge in radical or nerve-sparing prostatectomies is to minimize the neurological complications that can lead to impotence in about 10%-30% of cases and… more
Abstract:Robots need to know their location to map of their surroundings but without global positioning data they need a map to identify their surroundings and estimate their location. Simultaneous localization and mapping (SLAM) solves these dual problems at once. SLAM does not depend on any kind of… more
Abstract:Cryogenic propellants are important to NASA's missions. Improvements in cryogenic propellant storage and transfer are critical to future long duration NASA spacecraft and missions. Advanced Cooled Shield - IMLI (ACS-IMLI) is an innovative ultra high performance system in which an Advanced… more
Abstract:Solar Electric Propulsion drives down the cost of space missions by using its high propulsion efficiency to step down from one launch class to another. As launch costs can be up to a third of total mission costs, stepping down to a smaller rocket can be a mission enabling technology in today's… more
Abstract:An eye-safe, multispectral cross-track scan subsystem with a large receiver aperture and a narrow FOV is proposed for the NASA Cloud Physics Lidar to increase horizontal area coverage. The +/-15 degree cross-track scan capability will cover +/- 5 km from nadir at a 20 km altitude. The cross-track… more
Abstract:NASA has numerous missions that involve radar and radiometry. In the past, the practice has been to build each system as a one-off program, which makes MMIC design unattractive from a cost perspective. In an era of reduced budgets and the need for higher efficiencies both in R & D cost reduction… more
Abstract:A new detector evaluation method (DEM) is proposed to determine the response of graphene detectors to low fluxes of photons, neutral atoms/molecules, and ions in the space environment of high to ultra-high vacuum. The method, aimed mainly at evaluation for space applications of new graphene… more
Abstract:The unique built-in design features of the proposed mini pulse tube cryocooler avoid all thermal expansion issues enabling it to operate within a cold, 150 K environment. As such, the cooler addresses the need to prevent boiloff of cryogenic propellants on long duration remote missions.Due to its… more
Abstract:The proposed innovation is for enhanced sensor performance and high resolution imaging for Long Wave InfraRed (LWIR) and Medium Wave IR (MWIR) camera systems used in aerial imaging applications through integration with KeyW's advanced EO/IR Imaging eGimbal?(IeG) system. Increases in pixel… more
Abstract:Advanced x-ray observatories such as IXO and GenX will require thousands of thin shell mirror segments produced by replication using convex mandrels. Quality and cost effective manufacturing of these segments is proportional to the speed and effectiveness of the metrology we use in manufacturing and… more
Abstract:Acute challenges are faced by the designers of fluid systems for spacecraft because of the persistently unfamiliar and unforgiving low-g environment. For example, most fluid systems aboard spacecraft are impacted by the presence of capillary forces?a poor understanding of which has led to poorly… more
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