Abstract:DESCRIPTION (provided by applicant): Yearly influenza epidemics affect about 5 - 15% of the world's population and estimates of annual mortality range from 250,000 - 500,000, including approximately 30,000 deaths and 200,000 hospitalizations in the UnitedStates. In addition, the likelihood of a… more
Abstract:Washburn Therapeutics Inc. is developing biologically active gels that control inflammation by selectively neutralizing pro-inflammatory cytokines based on a technology being licensed exclusively by the company from Carnegie Mellon University. Preliminary results demonstrated that conjugates of… more
Abstract:DESCRIPTION (provided by applicant): A Phase II SBIR program of preclinical development is proposed for the development of an active specific immunotherapeutic called Cellarium for treatment of glial cell-based cancers. Successful completion of this project will confirm therapeutic effect and… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project proposes to develop an artificial trachea made from synthetic nanofibers that is seeded with the patient?s own stem cells in the operating room using a disposable, closed system seeding chamber. There currently are no commercially… more
Abstract:DESCRIPTION (provided by applicant): PROJECT SUMMARY This proposal is a Phase 1 proposal in response to The National Institute of Health Small Business Innovation Research (SBIR) Program call for proposals for the Cancer Diagnostics and Therapeutic AgentsEnabled By Nanotechnology (SBIR [U43/U44])… more
Abstract:DESCRIPTION (provided by applicant): Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness in people over age 60 in the developed world. Progression of this disease results in the loss of the ability to perform activitieshighly correlaed with quality of life. This… more
Abstract:This Small Business Innovation Research (SBIR) Phase II project should dramatically improve intersection safety and mobility in a practical way. Safety is measured by the risk of collision between pedestrians, bicycles and vehicles; safety is improved by better signal timing, warnings, and possibly… more
Abstract:DESCRIPTION (provided by applicant): Over one million prostate biopsies are performed in the US each year to diagnose approximately 200,000 cases of prostate cancer. The majority of these biopsies are performed needlessly. The overall objective of this project is to develop a secondary prostate… more
Abstract:Biogas & Electric LLCs proposed Phase I research will strive to demonstrate the existing opportunities for resource recovery and recycling at dairies and other concentrated animal feeding operations (CAFOs). Current recovery efforts are limited to energy from biogas combustion and a few struvite… more
Abstract:The effectiveness of synchrotron radiation science has been hindered by the limited availability of advanced diagnostics. In many cases, the capability to produce photon fluxes has outpaced the ability to detect and measure the resultant photons. Synchrotron applications are becoming more… more
Abstract:This proposal will serve as a pilot project for poor, rural, Southern counties with rich forestry resources. Arkansas and surrounding states have some of the highest poverty rates in the nation. Arkansas 19 million acres of forests represent more than half of the total land mass of this state. This… more
Abstract:In an effort to support the development of a domestic marine aquaculture industry, Zeigler Bros. Inc., (ZBI) proposes to continue its Phase I research by demonstrating the ability to scale up inclusion particle (IP) manufacturing. During Phase II ZBI will also demonstrate the efficacy of IOs for… more
Abstract:The TAU Performance System is a powerful and highly versatile profiling and tracing tool ecosystem for performance analysis of parallel programs. Developed over the last 15 years, TAU has evolved with each new generation of HPC systems and scales efficiently to hundreds of thousands of cores on the… more
Abstract:Currently, the most successful approach for table top soft-Xray and EUV (Extreme Ultra-Violet) sources, is that of High Harmonic Generation (HHG), where a high intensity pulses are used to drive frequency conversion from a noble gas in a hollow core fiber. This configuration allows phase matching,… more
Abstract:With the 4 billion tons of uranium estimated to be dissolved in the earth & apos;s oceans, an essentially unlimited resource is available to those with easy and affordable access. With decades of research towards the extraction of uranium from seawater, focus has been directed towards the… more
Abstract:At NOVATIO Engineering, our solution to this problem is practical and novel (and proven at a smaller scale): conversion of a lightweight gasoline generator to operate with diesel fuel or JP-8 in spark ignition mode. During the past year, with the help of CERDEC funding, Novatio has developed and… more
Abstract:Proposed here is an approach to modify the fuel supply line to existing commercial appliances to allow them to operate on JP-8 fuel, using a JP-8 blue flame technology, based on a patented fuel conditioner that has been shown to produce a clean, highly efficient combustion process from JP-8. Our… more
Abstract:Beginning from an advanced stage of development, this Phase II STTR project will produce designs and prototypes for a ricin-specific artificial antibody constructed using DNA origami. These novel constructs will provide both a capture function (mimicking the properties of an antibody) and intrinsic… more
Abstract:In this project, Parabon NanoLabs will employ its Essemblix(tm) Drug Development Platform, a combination of computer-aided design (CAD) software and DNA nano-fabrication technology, to produce artificial vaccines against the biothreat agent ricin on DNA origami decorated first with natural epitopes… more
Abstract:Li-ion battery calendar and cycle life degrade at elevated temperatures due to processes involving the interaction of electrolyte salt, solvents and battery electrode materials. The major factor impacting automotive Li-Ion battery pack safety is the use of high vapor pressure and low flashpoint… more
Abstract:ABSTRACT: PrivaTran will measure the radiation tolerance of new resistive memory materials and will design and fabricate advanced memristor-based architectures for nonvolatile random access memory (RAM) applications that are suitable for aerospace systems. The requirements for proper memory element… more
Abstract:ABSTRACT: The leading errors in computing future positions of satellites in Low Earth Orbit are generally due to inaccuracies in the thermospheric density and the prediction thereof. The use of Dynamic Calibration Atmosphere has reduced these traditional sources of error and variations seen in… more
Abstract:Deployable Space Systems, Inc. (DSS), and Space Systems Loral as a key subcontractor and potential commercial infusion partner, will focus the proposed SBIR Phase 2 program on the TRL 5/6 technology maturation / development of an affordable, lightweight, high power, maximum performance solar array… more
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