Abstract:This Small Business Innovative Research Phase I project is aimed at demonstrating that acyl glycinate surfactant can be produced by a novel bacterial fermentation route. The objective of this project is to construct a bacterial strain that produces acyl glycinate, and to provide a sample of that… more
Abstract:DESCRIPTION (provided by applicant): Quantitative characterization of tissue structure and function is one of the most challenging problems in Medical Imaging. Field of view, depth of interrogation, and resolution are critical features that dramatically impact image quality and information content.… more
Abstract:The basic need in a crisis situation, whether it is a natural or unnatural disaster, political or social unrest, or some combination, is relevant, timely and accurate information, filtered to present the most pertinent data to the decision makers. Commanders have unique information requirements due… more
Abstract:The focus of our Intelligence and Intuition for Enhanced Decision Making (I2EDM) Phase 1 research is to provide efficient and timely automated production and dissemination of information products in support of doctrinal Decision Points for the Company and below in austere environments. Operating in… more
Abstract:Modus Operandi proposes to continue the development of Inception, a collaborative intelligent service for searching, gathering, interpreting, validating, capturing, and documenting the characterization of stakeholder needs for Modeling and Simulation (M & S) systems. The first phase or the… more
Abstract:ABSTRACT: We propose to develop an assured information sharing framework for cloud-based systems that leverages our ongoing work in the areas of policy-based usage management and semantic interoperability. The development of this framework will involve the creation of a novel approach to… more
Abstract:The Modus Operandi Team proposes to design, develop, and demonstrate innovative technology to detect, prevent, and mitigate security threats at all levels within the cloud computing environment. Within the problem space, our objective is to provide measurable security in the cloud environment that… more
Abstract:The overall objective of the Phase I and Phase II proposed effort is to design and demonstrate the ability to develop a high-speed shock tolerant composite flywheel energy storage system (FESS) using a low cost manufacturing process. The Phase I tradeoff design studies will assess the FESS size,… more
Abstract:ABSTRACT: MiTi and its subcontractor are proposing an innovative integrated and low logistics footprint fueled hybrid solid oxide fuel cell (SOFC) and mesoscopic gas turbine engine generator (GTG) system with fuel-to-electricity efficiencies to 65%. The ultra-high speeds of the oil-free mesoscopic… more
Abstract:ABSTRACT: It is proposed to develop new thermal barrier coatings based on current MiTi Korolon coatings for the turbomachinery of the rocket engines. The proposed coating system will provide thermal and environmental protection and at the same time provides sufficient damping characteristics to… more
Abstract:DESCRIPTION (provided by applicant): Molecular Express specializes in the design and engineering of functionalized liposomes for drug delivery and vaccine development. In previous studies, an extensive set of liposome formulations were screened to establish the optimal lipid combination that meets… more
Abstract:DESCRIPTION: In response to PA-10-150, we will test the hypothesis that the VesiVax(R) Conjugatable Adjuvant Lipid Vesicle (CALV) platform can provide an efficient method to develop carbohydrate conjugate vaccines that stimulates superior immune responsesto unconjugated carbohydrate antigens and… more
Abstract:Roll to Roll (R2R) printing, or web printing involves the patterning of flexible materials such as plastics or metal foils. R2R processing is in use today by industry and many R2R processes already exist for etch and deposition. However R2R patterning of arbitrary patterns with thin residual layer… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will develop the use of unique artificial protein sequences, known as entropic bristles, to accelerate the study of protein structure by the method of X-ray crystallography. Many interesting proteins have proven to be difficult to… more
Abstract:DESCRIPTION: Tracing neuronal connections with lipophilic carbocyanine dyes has revolutionized neuroanatomical tract tracing and is an essential feature to understand development of brain connections in both control and mutant mice in particular since multiple colors of dyes can be used. More… more
Abstract:This Small Business Innovation Research (SBIR) Phase I project will establish the feasibility of developing a genetically-encoded biosensor to monitor levels of cyclic adenosine monophosphate (cAMP), an important second messenger component of drug signaling pathways. Unlike existing FRET-based… more
Abstract:Resodyn Corporation proposes to develop a novel cold chain system with a Lifetime Warranty for the vacuum container. The container composes a passive energy efficient system for transporting blood and pharmaceuticals in hostile environments for up to three days. Capacity is four 500 ml liter blood… more
Abstract:Resodyn Corporation proposes to develop a single tough thermoplastic polymer coating material and system solution for aluminum and composite boat hulls. The coating functions as an adhesive for attaching doubler plates. It encapsulates and prevents water from corroding metal substrates plus it is… more
Abstract:ABSTRACT: Resodyn Corporations proposed Functionalized Polyethylene (FPE) copolymer thermoplastic coating will overcome the shortcomings of the current ski coating. The FPE will provide the long-lasting, low friction, impact-resistant, abrasion resistant and hydrophobic properties required and… more
Abstract:Bonded composite materials offer considerable opportunity to reduce manufacturing cost, improve structural performance, and improve fuel efficiency of aircraft. However, bonded composite aircraft structures continue to be a challenge to manufacture due to the certification requirement to determine… more
Abstract:DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I project will develop a commercially-viable device that uses micro-scale acoustic streaming (low frequency sound energy) to deliver mixing to the interior of three-dimensional (3D) scaffolds used for tissue… more
Abstract:DESCRIPTION (provided by applicant): NeuroPlay Adventures addresses the need to develop innovative neuroscience educational tools to benefit children in kindergarten through 12th grade (K-12). The goals of this project are: (1) to develop mobile apps for tablets and smart phones and a web-site that… more
Abstract:ABSTRACT: In this program Morton Photonics will develop an Ultra-Low-Noise (ULN) Short Wave Infrared (SWIR) Hybrid Integrated Laser with low cost, size, weight and power (CSWAP) for operation between 1900nm and 2200nm. The ULN-SWIR laser is based on the hybrid-integration of a high-power SWIR… more
Abstract:This Small Business Innovation Program (SBIR) Phase I project will create a semiconductor-based laser with high power and the ultimate in low-noise performance besting all current semiconductor based lasers, and providing equivalent or better noise performance than the best fiber and solid-state… more
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