Award

Among a suite of synthetic biology methods, Afingen's APFL technology offers a robust path to produce high-value biochemicals from inedible biomass-derived substrates with minimal cis-genetic manipulation and improved genetic stability compared to conventional bio-engineering. By amplifying and/or reducing target compounds with unprecedented specificity and improved tolerance, engineered food-, feed-, and biofuel crops (e.g. switchgrass, wheat, canola, corn, soybeans, alfalfa, tomato, potato) may offer higher yields of biomass and enhance degradation in the inedible biomass to facilitate nutrient recycling. This STTR Phase I application by Afingen, Inc. and Lawrence Berkeley National Laboratory is aimed at generating significantly improved rotation crops, wheat and canola,with a combination of three beneficial traits: [1] accelerated rooting growth, [2] increased grain yield and vegetative biomass, and [3] enhanced degradability of inedible biomass.