ACCELERATED OSSEOINTEGRATION

Award Information

Agency: Department of Health and Human Services

Branch: N/A

Contract: N/A

Agency Tracking Number: 16524

Amount: $50,000.00

Phase: Phase I

Program: SBIR

Solicitation Topic Code: N/A

Solicitation Number: N/A

Timeline

Solicitation Year: N/A

Award Year: 1991

Award Start Date (Proposal Award Date): N/A

Award End Date (Contract End Date): N/A

Small Business Information

Medical Laser Research & Devel

P O Box 539

Malden, MA 02148

United States

DUNS: N/A

HUBZone Owned: No

Woman Owned: No

Socially and Economically Disadvantaged: No

Principal Investigator

Name: Bourgelais, Donna B
Title: Principal Investigator
Phone: (617) 322-8693

Business Contact

Name: 1 R43 DE09787-01A1
Phone: () -

Research Institution

N/A

Abstract

THE PROGRAM WILL INVESTIGATE THE EFFECT ON BONE GROWTH OF PHOTOLYTIC OXYGEN RELEASE. BY IRRADIATING TISSUE WITH LIGHT IN THE APPROPRIATE WAVELENGTH AND IRRADIANCE RANGE, INCREASED OXYGEN RELEASE IN THE CAPILLARY STRUCTURE MAY BE ACHIEVED, THUS INCREASING THE OXYGEN ACTUALLY AVAILABLE TO TISSUE AND THE RATE OF HEALING IN INJURED OR DISEASED TISSUE. THE SPECIFIC AIM OF PHASE I IS TO MEASURE THE RATE OF GONE GROWTH IN AN OPTICAL BONE GROWTH CHAMBER IN A RABBIT MODEL WITH AND WITHOUT THE APPLICATION OF PHOTODISSOCIATING LIGHT. DEMONSTRATION AND QUANTIFICATION OF THIS EFFECT WILL ALLOW THE DESIGN OF DEVICES BASED ON PHOTODISSOCIATION FOR CLINICAL USE. AREAS OF APPLICATION INCLUDE ANY SITUATION WHERE SOME BLOOD FLOW EXISTS, BUT GREATER OXYGEN AVAILABILITY IS DESIRED. IN PARTICULAR, IN THE AREA OF DENTAL IMPLANTS, RAPID INTEGRATION OF OSSEOUS IMPLANTS FOR DENTAL RECONSTRUCTION IS DESIRABLE IN ORDER TO SHORTEN THE PERIOD OF EDENTULISM EXPERIENCED WHILE THE IMPLANT FOUNDATION IS INTEGRATED INTO THE STRUCTURE OF THE JAW. ADDITIONAL APPLICATIONS INCLUDE BOTH IMPLANT INTEGRATION AND BONE REPAIR FOLLOWING FRACTURE.

* Information listed above is at the time of submission. *

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ACCELERATED OSSEOINTEGRATION