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Automated Microscopic Malaria Diagnosis

Award Information
Agency: Department of Defense
Branch: Army
Contract: W81XWH-08-C-0106
Agency Tracking Number: A08A-036-0118
Amount: $100,000.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: A08-T036
Solicitation Number: 2008.A
Solicitation Year: 2008
Award Year: 2008
Award Start Date (Proposal Award Date): 2008-07-23
Award End Date (Contract End Date): 2009-02-28
Small Business Information
33 Sheridan Road
Wellesley, MA 02481
United States
DUNS: 059739495
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 David Zahniser
 (781) 237-7429
Business Contact
 David Zahniser
Title: President
Phone: (781) 237-7429
Research Institution
 Max Diem
316 Hurting Hall 360 Huntington Avenue
Boston, MA 2115
United States

 (617) 373-2922
 Nonprofit College or University

In this project we will develop a computerized microscope based imaging system for field testing that will allow location and quantization of malarial parasites (trophozoites). The system will automatically scan a blood smear, locating the portions of the smear that are adequate for analysis and then counting the total number of red cells and the number of red cells containing parasites. The system will be capable of displaying digital images of all candidate parasites for confirmation by an operator if needed, and will allow relocation to objects located on the slides. The computer system will allow the operator to observe classes of located candidates (for example, high probability of being a parasite vs low probability) and confirm or reject objects. Total counts will be automatically updated during the editing process. High speed and high accuracy through sophisticated multi-spectral analysis are primary objectives of this project.

* Information listed above is at the time of submission. *

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