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Biodegradable Polylactide-Co Glycolide Medical Cements

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1 R43 AR42800-01A1,
Agency Tracking Number: 29158
Amount: $99,990.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Solicitation Year: N/A
Award Year: 1995
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
21-C Olympia Avenue
Woburn, MA 01801
United States
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Larry Nichols
 () -
Business Contact
Phone: () -
Research Institution

Osteomyelitis is a serious orthopedic problem, and its prevention or treatment using systemic antibcomplications and is often unsuccessful. The use of polymethylmethacrylate beads or bone cement to dto bone sites does reduce the incidence of post- operative bone infections, but these non-porous poldrug delivery vehicles, and because they are non-biodegradable materials they cannot be used where bdesired. BIOTEK has recently discovered new methods which for the first time allow medical cements tporous, biodegradable, FDA-approved polylactide- coglycolide. These new cements are produced using hand sintering agents, and their workability, cure time, shrinkage, porosity, and strength are subjecprepare and characterize biodegradable cements for use in bone cavities, introduce a prototype antibdemonstrate sustained drug delivery in vitro, and test the most promising formulation in vivo in a r

* Information listed above is at the time of submission. *

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