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Data acquisition system for multiplex analysis of color encoded particles

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 4R42CA140109-02
Agency Tracking Number: R42CA140109
Amount: $2,284,700.00
Phase: Phase II
Program: STTR
Solicitation Topic Code: NCI
Solicitation Number: PHS2010-2
Solicitation Year: 2010
Award Year: 2010
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
United States
DUNS: 831599621
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 (516) 770-5428
Business Contact
Phone: (517) 770-5428
Research Institution
 State University Of New York
State University Plaza
ALBANY, NY 12246-
United States

 () -
 Nonprofit College or University

DESCRIPTION (provided by applicant): The main goal of this project is a development of the high throughput data acquisition system based on single photon spectrometer which enables detection and highly accurate recognition of sets containing millions of stochastically encoded microparticles and the validation of this system using genome-wide copy number analysis as a model system. As an outcome of this project, we expect dramatic advancement in quantitative molecular biology and medicine, because it will enable true absolute measurements of nucleic molecules and genetic markers of gene-related diseases independent of experimental designs, chemistries, assumptions, etc. The ensuing data will be standardized, and will become comparable between different experiments, tests, or clinical trials conducted at various sites. Moreover, national databases will be accumulated as a result of extensive population-wide tests/measurements. Finally, based only on such data it will become possible to establish norm and pathology ranges, cut-off criteria or threshold levels of the nucleic species for molecular diagnosis of gene-based disorders, and, thereby, to actually establish the field of molecular diagnostics.

* Information listed above is at the time of submission. *

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