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Development of an Automated Precision Coating System for SAW-Based Chemical Sensors

Award Information
Agency: Department of Defense
Branch: Office for Chemical and Biological Defense
Contract: DAAD19-01-C-0072
Agency Tracking Number: C011-0084
Amount: $69,996.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Solicitation Year: N/A
Award Year: 2001
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
2520 W. 237th Street
Torrance, CA 90505
United States
DUNS: 033449757
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Srivatsa Venkatasubbarao
 Research Scientist
 (310) 530-7130
Business Contact
 Robert Lieberman
Title: Sr. Vice President & CTO
Phone: (310) 530-7130
Research Institution

Intelligent Optical Systems (IOS), in collaboration with Tetracore LLC (Rockville, MD), proposes to design, construct, and demonstrate a novel, portable, self-contained, imaging microarray reader (referred to here as Biomapper) to rapidly identify theexposure of Army personnel to biological warfare agents, chemical agents, physical stress, infectious diseases, and other medical conditions that would impact their physical performance. IOS's Biomapper will be based on a novel imaging technique that willmonitor biochemical-binding events on the surface of a microarray. The monitored area will be approximately 25mm in diameter and have a spatial resolution of about 10 microns, resulting in the fully parallel, continuous readout of about 100,000 sensorfields. In Phase I, IOS will demonstrate a proof-of-concept reader using humanb-actin messenger RNA as the model target.In Phase II of this project the optical, electronic, and fluidic components will be integrated to create a portable unit for field use.There are many applications for a portable microarray unit. The proposed reader will find applications in the military as a diagnostic tool and as a prognostic tool. Clinical laboratories and emergency medical personnel are also likely to benefit from thisreader. The reader could also be used as a diagnostic instrument, leading to more rapid treatment and a reduction in medical costs. This device will also be used in the pharmaceutical industry, biotech industries, and research laboratories.

* Information listed above is at the time of submission. *

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