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Fast, easy, reliable first responder bioterrorism detection system

Award Information
Agency: Department of Homeland Security
Branch: N/A
Contract: NBCHC060032
Agency Tracking Number: 0521157
Amount: $99,600.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: H-SB05.2-001
Solicitation Number: N/A
Solicitation Year: 2005
Award Year: 2005
Award Start Date (Proposal Award Date): 2006-01-27
Award End Date (Contract End Date): 2006-08-15
Small Business Information
750 Alfred Nobel Drive
Hercules, CA 94547-
United States
DUNS: 117194642
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Zwick Michael
 VP New Technologies
 (510) 964-9700
Business Contact
 Heather Koshinsky
Title: CEO
Phone: (510) 964-9700
Research Institution

The proposed research is to determine feasibility of developing a stable, simple, rapid method of detecting the nucleic acid (NA) from bioterrorism agents. This method would be based on Investigen?s novel and elegant ?smartDNA? technology. This system utilizes a peptide nucleic acid probe cocktail to produce a rapid color change when probes hybridize to complementary NA sequences. Phase 1 will: 1) demonstrate detection of multiple agents; 2) develop collection hardware and consumables; 3) develop processing hardware and consumables, 4) develop detection hardware and consumables, and 5) validate system performance. With this validation of the feasibility of developing a smartDNA first responder bioterrorism agent detection system, we would develop the system to detect category A bioterrorism agents. The intention is to create a commercial diagnostic assay to detect bioterrorism agents that is so simple and stable that one could be in every locality. Such a test could be used in peripheral locations away from a central lab. This would help response to and may even deter bioterrorism attacks. smartDNA is uniquely suited to situations where there is not easy access to a central lab and a NA test is ideal. These include disease assessment in public health settings and agriculture.

* Information listed above is at the time of submission. *

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