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Miniaturized Sample Preparation Module

Award Information
Agency: Department of Defense
Branch: Office for Chemical and Biological Defense
Contract: DAAD13-02-C-0045
Agency Tracking Number: C2-0104
Amount: $0.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Solicitation Year: N/A
Award Year: 2002
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
1021 N. Kellogg St.
Kennewick, WA 99336
United States
DUNS: 016541877
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Andrew Kamholz
 Principal Investigator
 (509) 737-8383
Business Contact
 Tamela Stone
Title: Sr. Contract Specialist
Phone: (509) 737-8383
Research Institution

"The detection of biological materials used by terrorists and in warfare has become a high priority throughout the world. Thus, the need for rapid microbiological monitoring of water, air, surfaces, and food for the military has accelerated development offaster diagnostic technologies. Recent advances in detection methods based on PCR amplification of the genetic material, antigen and antibody pairs, and direct mass spectrometry of biological samples promise more rapid identification of pathogens ofmilitary significance. To advance the laboratory prototypes toward field-ready prototypes, integration, portability and contamination issues must be addressed. For example, the collection and replication of nucleic acids by PCR requires that the sample becleaned prior to detection. The goals of this project include development of sophisticated sample preconditioning subsystems for the isolation and pretreatment of DNA samples. Another substantial goal is the non-trivial fluidic interconnection of anaerosol collector to the sample preconditioning unit, providing a fast and seamless means of collecting bioparticules and preparing a sample for PCR. Together, the attainment of these goals will create an integrated system allowing the most accurate rapiddetection available."

* Information listed above is at the time of submission. *

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