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Novel CSF biomarker to predict impaired cognition in HIV

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 4R42NS046997-02
Agency Tracking Number: NS046997
Amount: $0.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Timeline
Solicitation Year: N/A
Award Year: 2004
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
8080 NORTH STADIUM DRIVE SUITE 1100
HOUSTON, TX 77054
United States
DUNS: N/A
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 DANA GIULIAN
 (713) 798-6970
 dgiulian@bcm.tmc.edu
Business Contact
 LAURA JACOBUS
Phone: (609) 921-7447
Email: IRJACOBUS@AOL.COM
Research Institution
N/A
Abstract

DESCRIPTION (provided by applicant): The focus of this project is to explore the relationship between inflammatory cells and cognitive dysfunction in populations with HIV-1 infection. Extensive work has found that a biomarker is detected in lumbar cerebrospinal fluid of HIV(+) subjects with impaired cognition. Presently there are no suitable clinical tests to identify early neuro-inflammatory injury to neurons in such disorders as HIV-1 dementia. The ability to identify and treat HIV(+) populations before the onset of irreversible brain damage is highly desirable and forms the basis for this STTR proposal.

* Information listed above is at the time of submission. *

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