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RIGID SUPPORTS FOR SOLID-PHASE PEPTIDE SYNTHESIS

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 7273
Amount: $50,000.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Timeline
Solicitation Year: N/A
Award Year: 1987
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
2980 Kerner Boulevard
San Rafael, CA 94901
United States
DUNS: N/A
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 DEREK HUDSON PHD
 (415) 459-3907
Business Contact
Phone: () -
Research Institution
N/A
Abstract

PRELIMINARY RESEARCH PERFORMED AT BIOSEARCH, INC. HAS CONFIRMED THAT MODIFIED INORGANIC MATERIALS MAY HAVE SUPERIOR PHYSICAL AND CHEMICAL PROPERTIES FOR ATTACHMENT AND ASSEMBLY OF PEPTIDE CHAINS DURING SOLID-PHASE PEPTIDE SYNTHESIS. THESE SUPPORTS ARE BELIEVED TO PROVIDE A MORE MORE FAVORABLE ENVIRONMENT FOR THE CHEMICAL REACTIONS INVOLVED, AND THEIR RIGIDITY IS EXPECTED TO MINIMIZE PEPTIDE AGGREGATION PROBLEMS ENCOUNTERED IN THE SYNTHESIS OFCOMPLEX PEPTIDES WITH CONVENTIONAL POLYMERIC SUPPORTS. MANYAREAS OF BIOTECHNOLOGY, AS WELL AS BIOCHEMICAL AND PHARMACEUTICAL RESEARCH, WILL BENEFIT FROM THE ANTICIPATED EFFICIENCY OF SYNTHESIS AND PURITY OF PRODUCTS RESULTING FROM THIS INNOVATION. PROGRESS IN THESE AREAS IS OFTEN LIMITED BY THE CAREFUL PURIFICATION AND CHARACTERIZATION REQUIRED FOR THE HETEROGENOUS PRODUCTS CURRENTLY OBTAINED.

* Information listed above is at the time of submission. *

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