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Vaccine Approaches to Treatment of Hepatitis C Infection

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: N/A
Agency Tracking Number: 29134
Amount: $749,544.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Solicitation Year: N/A
Award Year: 1998
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
3525 John Hopkins Court
San Diego, CA 92121
United States
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Alessandro Sette
 () -
Business Contact
Phone: () -
Research Institution

The overall aim of our studies is to derive a potential HCV vaccine, based on the induction of HCV-To do so, we will identify a synthetic formulation composed of at least two A2-restricted CTL epitopconserved regions of the HCV genome. Such formulation will also contain universal T helper epitopesdemonstrated to be efficacious in inducing specific A2-restricted CTL responses in vivo, utilizing Hmice. In parallel studies additional potential epitopes specific for several of the major HLA types

* Information listed above is at the time of submission. *

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