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IGF OT IGF SBIR PHASE I TOPIC CELL BASED MODELS FOR PROSTATE CANCER HEALTH DISPARITY RESEARCH

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 261201600038C-0-0-0
Agency Tracking Number: N43CA160038
Amount: $224,687.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: NCI
Solicitation Number: N/A
Timeline
Solicitation Year: 2016
Award Year: 2016
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
1 RESEARCH CT, STE 450
ROCKVILLE, MD 20850-6252
United States
DUNS: 078720415
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 KATHLEEN SEARS
 (204) 271-0641
 dritscha@georgetown.edu
Business Contact
 KATHLEEN SEARS
Phone: (204) 271-0641
Email: dritscha@georgetown.edu
Research Institution
N/A
Abstract

Prostate cancer health disparities studies have shown that African American AA men are athigher risk for developing prostate cancer as well as at higher risk of cancer specific death ratesas compared to Caucasian American CA men The causes of disparities have been attributedto socioeconomic differences environmental exposures and biological factors Most disparitiesstudies have been population based in part due to the lack of relevant in vitro and in vivo modelsto support biological studies In this Phase I proposal we will develop an annotated AA prostateepithelial cancer cell line with donor matched normal prostate epithelial cells and bio bankedreference prostate tissues To support the feasibility of establishing prostate cancer cell linesfrom AA men in a subsequent Phase II application we will prepare written protocols for tissuecollection processing establishment of conditionally reprogrammed cells and the reagentsnecessary for performing studies with these cells We will determine the commercial feasibilityfor cell distribution and reagent marketing through a private public partnership

* Information listed above is at the time of submission. *

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