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IGF OT IGF PROXIMITY DNA EXCHANGE IMAGING

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 261201600050C-0-0-0
Agency Tracking Number: N43CA160050
Amount: $299,717.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: NCI
Solicitation Number: N/A
Timeline
Solicitation Year: 2016
Award Year: 2016
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
763D CONCORD AVE
CAMBRIDGE, MA 21381
United States
DUNS: 079962117
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 YIFAN YANG
 (617) 945-2662
 stephanie.walter@ultivue.com
Business Contact
 YIFAN YANG
Phone: (617) 945-2662
Email: stephanie.walter@ultivue.com
Research Institution
N/A
Abstract

A great challenge in microscopic imaging of biological and medical samples e g tissue sections is to achieve high sensitivity high specificity high multiplexing and high resolution preferably beyond the diffraction limit simultaneously This SBIR proposal addresses this challenge by developing a novel technology platform called Proximity DNA Exchange Imaging As a result of the studies proposed here a panel of imaging reagents three high value cancer related biomarkers phosphorylated AKT MET and CTNNB will be established Compared to previous and current proximity based immunoassay platforms Proximity DNA Exchange Imaging is highly advantageous with regard to ease of implementation versatility depth of multiplexed information and spatial resolution This technology will offer the research and medical community methods to investigate molecular details of biology with unprecedented precision and information content It also has broad applications in areas such as digital pathology and high content screening for drug discovery

* Information listed above is at the time of submission. *

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